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Effects of acrylamide in the presence of vitamin E on sperm parameters, chromatin quality, and testosterone levels in mice

Anvari M, Talebi AR, Mangoli E, Shahedi A, Ghasemi MR, Pourentezari M

Objective: The present study investigated sperm chromatin quality and testosterone levels in acrylamide-treated mice and the possible protective effects of vitamin E on the fertility potential of spermatozoa. Methods: Thirty-two...
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Evaluation of sperm protamine deficiency and apoptosis in infertile men with idiopathic teratozoospermia

Dehghanpour F, Tabibnejad N, Fesahat F, Yazdinejad F, Talebi AR

OBJECTIVE: Sperm morphology plays an important role in infertility, especially in cases of defects in the heads of spermatozoa. Tapered-head or elongated-head spermatozoa are examples of morphological abnormalities. The aim...
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Protective effects of curcumin on chromatin quality, sperm parameters, and apoptosis following testicular torsion-detorsion in mice

Shahedi A, Talebi AR, Mirjalili A, Pourentezari M

Objective: The chief outcome of testicular torsion in clinical and experimental contexts is testicular ischemia. Curcumin, a compound with anti-inflammatory and antioxidant properties, has fascinated researchers and clinicians for its...
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The effects of sesame oil and different doses of estradiol on testicular structure, sperm parameters, and chromatin integrity in old mice

Mohammadzadeh M, Pourentezari M, Zare-Zardini H, Nabi A, Esmailabad SG, Khodadadian A, Talebi AR

Objective: Studies of the effects of estrogens on the male reproductive system have emphasized the role of these hormones in male fertility. Sesame oil has many phytoestrogenic compounds and may...
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The effect of vitamin C on the gene expression profile of sperm protamines in the male partners of couples with recurrent pregnancy loss: A randomized clinical trial

Hamidian S, Talebi AR, Fesahat F, Bayat M, Mirjalili , Ashrafzadeh HR, Rajabi M, Montazeri , Babaei S

Objective: Since sperm abnormalities are known to be a major reason for recurrent pregnancy loss (RPL), any defects in DNA structure and chromatin condensation can place embryos at risk in...
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The effect of lipopolysaccharide from uropathogenic Escherichia coli on the immune system, testis tissue, and spermatozoa of BALB/c mice

Khanmohammad KR, Khalili MB, Sadeh M, Talebi AR, Astani A, Shams A, Zare F

Objective: Uropathogenic Escherichia coli is known to cause urinary tract infections, and the endotoxin (lipopolysaccharide [LPS]) of this bacterium may cause deficiencies of sperm quality and morphology. In the present...
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Sperm chromatin and DNA integrity, methyltransferase mRNA levels, and global DNA methylation in oligoasthenoteratozoospermia

Rahiminia , Yazd EF, Fesahat F, Moein MR, Mirjalili , Talebi AR

OBJECTIVE: To investigate sperm chromatin/DNA integrity, global DNA methylation, and DNMT mRNA transcription in men with oligoasthenoteratozoospermia (OAT) compared with normozoospermic men. METHODS: Semen samples from 32 OAT patients who comprised...
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