- Duodenal Implications in the Pathophysiology of Functional Dyspepsia
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Lee KJ, Tack J
- KMID: 2326158
- J Neurogastroenterol Motil.
- 2010 Jul;16(3):251-257.
Functional dyspepsia (FD) is a heterogeneous disorder associated with diverse pathophysiologic mechanisms. Studies have shown duodenal implications in the pathophysiology of FD. Duodenal hypersensitivity to acid, increased duodenal acid exposure,... -
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- Gastroparesis: Current Concepts and Management
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Masaoka T, Tack J
- KMID: 2284058
- Gut Liver.
- 2009 Sep;3(3):166-173.
Delayed gastric emptying in the absence of mechanical obstruction is referred to as gastroparesis. Symptoms that are often attributed to gastroparesis include postprandial fullness, nausea, and vomiting. Although tests of... -
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- Gastrointestinal Motility Changes and Myenteric Plexus Alterations in Spontaneously Diabetic Biobreeding Rats
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Demedts I, Masaoka T, Kindt S, De Hertogh G, Geboes K, Farre R, Vanden Berghe P, Tack J
- KMID: 2325788
- J Neurogastroenterol Motil.
- 2013 Apr;19(2):161-170.
BACKGROUND/AIMS: Type 1 diabetes is often accompanied by gastrointestinal motility disturbances. Vagal neuropathy, hyperglycemia, and alterations in the myenteric plexus have been proposed as underlying mechanism. We therefore studied the... -
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- Validation of Octanoate Breath Test for Measuring Gastric Emptying in Rats
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Demedts I, Vanormelingen C, Van Billoen H, Vanuytsel , Farre R, Masaoka T, Verbruggen A, Verbeke K, Vanden Berghe P, Tack J
- KMID: 2325789
- J Neurogastroenterol Motil.
- 2013 Apr;19(2):171-178.
BACKGROUND/AIMS: Lack of simple and repeatable tests hampers gastric emptying studies in rats. The aim of this study was to adapt the 14C-octanoate solid gastric emptying breath test for application... -
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- Concise Review: Applicability of High-resolution Manometry in Gastroesophageal Reflux Disease
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Jandee S, Keeratichananont S, Tack J, Vanuytsel T
- KMID: 2534312
- J Neurogastroenterol Motil.
- 2022 Oct;28(4):531-539.
- doi: 10.5056/jnm22082
Manometry, particularly high-resolution manometry is the preferred diagnostic tool used to evaluate esophageal motor function. This investigation is strongly indicated in the setting of dysphagia, but is also useful in... -
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- Nocturnal Gastroesophageal Reflux Revisited by Impedance-pH Monitoring
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Fornari F, Blondeau K, Mertens V, Tack J, Sifrim D
- KMID: 2326208
- J Neurogastroenterol Motil.
- 2011 Apr;17(2):148-157.
BACKGROUND/AIMS: Impedance-pH monitoring allows detailed characterization of gastroesophageal reflux and esophageal activity associated with reflux. We assessed the characteristics of nocturnal reflux and esophageal activity preceding and following reflux. METHODS: Impedance-pH... -
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- Effect of Prucalopride in the Treatment of Chronic Constipation in Asian and Non-Asian Women: A Pooled Analysis of 4 Randomized, Placebo-controlled Studies
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Ke M, Tack J, Quigley EM, Zou D, Choi SC, Leelakusolvong S, Liu A, Kim J
- KMID: 2381209
- J Neurogastroenterol Motil.
- 2014 Oct;20(4):458-468.
- doi: 10.5056/jnm14029
BACKGROUND/AIMS: To compare the efficacy and safety of prucalopride, a novel selective high-affinity 5-hydroxytryptamine type 4 receptor agonist, versus placebo, in Asian and non-Asian women with chronic constipation (CC). METHODS: Data... -
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- Factors Predictive of Treatment-Emergent Adverse Events of Prucalopride: An Integrated Analysis of Four Randomized, Double-Blind, Placebo-Controlled Trials
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Leelakusolvong S, Ke M, Zou D, Choi SC, Tack J, Quigley EM, Liu A, Kim J
- KMID: 2380766
- Gut Liver.
- 2015 Mar;9(2):208-213.
- doi: 10.5009/gnl14290
BACKGROUND/AIMS: This integrated analysis aimed to identify the factors associated with the most frequently reported treatment-emergent adverse events (TEAEs) in Asian and non-Asian patients with chronic constipation (CC) who receive... -
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