- Effect of Capsaicin on Immune Responses, Anaphylaxis and Tumorigenesis in Mice
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Ha TY, Song WJ, Park JS, Ko YS, Ha HJ
- KMID: 1548224
- Korean J Immunol.
- 1997 Jun;19(2):229-244.
It has been known that the interconnection between the gervous, endocrine and immune system are largely mediated through regulatory soluble factors such as neruopeptides, cytokines and hormones. Capsaicin, the pungent... -
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- A polymerphism of the angiorensin-converting enzyme gene according to the asthma severity
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Cho JY, Cha DR, Han SA, Lee SY, Lee SH, Kang SY, Shim JJ, Kang KH, Yoo SH, In KH
- KMID: 2286102
- J Asthma Allergy Clin Immunol.
- 1998 Dec;18(4):656-661.
BACKGROUND: The angiotensin-converting enzyme (ACE) has a major role in the degradation of bradykinin, tachykinin, substance P which are associated with bronchial hyperresponsiveness and inflammation. The other role of ACE is the... -
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- Effects of Substance P on the Cell Proliferation and IL-2 Production of T Lymphocyte
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Moon JK, Choi BS, Lee SC, Kim HS
- KMID: 2057009
- J Korean Acad Periodontol.
- 1997 Dec;27(4):805-818.
- doi: 10.5051/jkape.1997.27.4.805
Immune responses of periodontal tissue may be regulated by products of sensory afferent nerve endings such as neuropeptides. Substance P(SP), a tachykinin neuropeptide, has been previously reported to stimulate the... -
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- Effects of Sensory Denervation by Neonatal Capsaicin Treatment on Cytokine Production and Various Immune Responses
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Ha TY, Lee JH, Park JS, Ha HJ, Kim YH
- KMID: 1550769
- Korean J Immunol.
- 1999 Sep;21(3):193-208.
Capsaicin, the pungent principle of hot peppers, is a neurotoxin that depletes unmyelinated primary sensory neurons (polymodal nociceptors) of neuropeptides like tachykinins. However, the role of capsaicin-sensitive sensory nerve in... -
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- The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments
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Farzaei MH, Bahramsoltani R, Abdollahi , Rahimi R
- KMID: 2433449
- J Neurogastroenterol Motil.
- 2016 Oct;22(4):558-574.
- doi: 10.5056/jnm16001
Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral hypersensitivity (VH) is a multifactorial process... -
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- Expression of Substance P in the Experimental Diabetic Rat Retina
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Lee SM, Park SJ, Kang TH, Chung JW, Chun MH, Oh SJ
- KMID: 1937827
- Korean J Anat.
- 2006 Apr;39(2):159-167.
Substance P (Sub P) being composed of 11 amino acids sequence is a kind of tachykinin family peptides. It has been known that this substance plays a role of neurotransmitter... -
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- Effects of Capsaicin on Production of Cytokines and Nitric Oxide, Salmonella Infection and NF-kappa B Activation
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Ha TY, Im SY, Park JS, Ha HJ, Choi DY
- KMID: 1928287
- Korean J Immunol.
- 1998 Sep;20(3):349-363.
"Capsaicin, the pungent principle of hot peppers, is a neurotoxin that depletes primary sensory neurons of neuropeptides like tachykinin. The objectives of these experiment was to examine the effects of... -
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- Effects of FK224, a NK1 and NK2 Receptor Antagonist, on Plasma Extravasation of Neurogenic Inflammation in Rat Airways
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Shim JJ, Lee SY, Lee SH, Park SM, Seo JK, Cho JY, In KH, Yoo SH, Kang KH
- KMID: 2128554
- Tuberc Respir Dis.
- 1995 Oct;42(5):744-751.
- doi: 10.4046/trd.1995.42.5.744
BACKGROUND: Asthma is an inflammatory disease because there are many inflammatory changes in the asthmatic airways. Axon reflex mechanisms may be involved in the pathogenesis of asthma. Sensory neuropeptides are... -
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