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Immunological abnormalities in patient with IgA nephropathy

Ihm CG, Woo JT, Chang YW, Kwon OS, Kim MJ

T cell immunity and phagocytic activity were studied in the blood of patients with IgA nephropathy in order to clarify their roles in the pathogenesis of IgA nephropathy. The percentages...
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Sequential evolution of IL-17 responses in the early period of allograft rejection

Min SI, Ha J, Park CG, Won JK, Park YJ, Min SK, Kim SJ

In addition to CD4+CD25+Foxp3+ regulatory T (T(reg)) cells which protect against autoimmune tissue injury, IL-17-producing CD4+ T (Th17) cells have been recently described and shown to play a crucial role...
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Recent Advances in the Concept and Pathogenesis of IgG4-Related Disease in the Hepato-Bilio-Pancreatic System

Okazaki K, Yanagawa M, Mitsuyama , Uchida K

Recent studies have proposed nomenclatures of type 1 autoimmune pancreatitis (AIP) (IgG4-related pancreatitis), IgG4-related sclerosing cholangitis (IgG4-SC), IgG4-related cholecystitis, and IgG4-related hepatopathy as IgG4-related disease (IgG4-RD) in the hepato-bilio-pancreatic system....
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CD4+CD25highFoxP3+ Regulatory T-cells in Hematologic Diseases

Moon HW, Kim BH, Park CM, Hur M, Yun YM, Kim SY, Lee MH

BACKGROUND: CD4+CD25+ regulatory T-cells (Tregs) play a critical role in immune responses. We explored the status of Tregs in neoplastic and autoimmune hematologic diseases. We also evaluated the technical aspects...
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Expression of TIM-3, Human beta-defensin-2, and FOXP3 and Correlation with Disease Activity in Pediatric Crohn's Disease with Infliximab Therapy

Kim MJ, Lee WY, Choe YH

BACKGROUND/AIMS: This study investigated the expression of T cell immunoglobulin- and mucin-domain-containing molecule 3 (TIM-3), human beta-defensin (HBD)-2, forkhead box protein 3 (FOXP3), and the frequency of CD4+ CD25+ FOXP3+...
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B cell-associated immune profiles in patients with end-stage renal disease (ESRD)

Kim KW, Chung BH, Jeon EJ, Kim BM, Choi BS, Park CW, Kim YS, Cho SG, Cho ML, Yang CW

  • KMID: 1387357
  • Exp Mol Med.
  • 2012 Aug;44(8):465-472.
Most of the previous studies on immune dysregulation in end-stage renal disease (ESRD) have focused on T cell immunity. We investigated B cell subpopulations in ESRD patients and the effect...
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