- Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia
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Jeon GW, Sheldon RA, Ferriero D
- KMID: 2469014
- Korean J Pediatr.
- 2019 Dec;62(12):444-449.
- doi: 10.3345/kjp.2019.00850
BACKGROUND: Sixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does... -
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- Antioxidant and antiobesity activities of oral treatment with ethanol extract from sprout of evening primrose (Oenothera laciniata) in high fat diet-induced obese mice
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Kwak CS, Kim MJ, Kim SG, Park S, Kim IG, Kang HS
- KMID: 2466667
- J Nutr Health.
- 2019 Dec;52(6):529-539.
- doi: 10.4163/jnh.2019.52.6.529
PURPOSE: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL... -
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- Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial
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Eshghi F, Bakhshimoghaddam F, Rasmi Y, Alizadeh M
- KMID: 2461099
- Clin Nutr Res.
- 2019 Oct;8(4):318-328.
- doi: 10.7762/cnr.2019.8.4.318
Obesity is a substantial public health challenge across the globe. The use of resistant starch has been proposed as a probable management strategy for complications of obesity. We investigated the... -
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- Antioxidant action of hypoxic conditioned media from adipose-derived stem cells in the hepatic injury of expressing higher reactive oxygen species
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Hong HE, Kim OH, Kwak BJ, Choi HJ, im KH, Ahn J, Kim SJ
- KMID: 2459313
- Ann Surg Treat Res.
- 2019 Oct;97(4):159-167.
- doi: 10.4174/astr.2019.97.4.159
PURPOSE: Almost all liver diseases are known to be accompanied by increased levels of reactive oxygen species (ROS), regardless of the cause of the liver disorder. However, little is known... -
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- Heterologous Expression of Rhizopus Oryzae CYP509C12 Gene in Rhizopus Nigricans Enhances Reactive Oxygen Species Production and 11α-Hydroxylation Rate of 16α, 17-Epoxyprogesterone
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Shen C, Gao X, Li T, Zhang J, Gao Y, Qiu L, Zhang G
- KMID: 2470141
- Mycobiology.
- 2019 Sep;47(3):301-307.
- doi: 10.1080/12298093.2019.1630201
The 11α-hydroxylation of 16α, 17-epoxyprogesterone (EP) catalyzed by Rhizopus nigricans is crucial for the steroid industry. However, lower conversion rate of the biohydroxylation restricts its potential industrial application. The 11α-steroid... -
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- Anti-oxidative Effect of Piperine from Piper nigrum L. in Caenorhabditis elegans
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Park HM, Kim JH, Kim DK
- KMID: 2459969
- Nat Prod Sci.
- 2019 Sep;25(3):255-260.
- doi: 10.20307/nps.2019.25.3.255
Piper nigrum L. (Piperaceae), which is a well-known food seasoning, has been used as a traditional medicine for the treatment of vomiting, abdominal pain, diarrhea and anorexia in Korea, China... -
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- Cyclosporin A aggravates hydrogen peroxide-induced cell death in kidney proximal tubule epithelial cells
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Moon D, Kim J
- KMID: 2459547
- Anat Cell Biol.
- 2019 Sep;52(3):312-323.
- doi: 10.5115/acb.18.192
Cyclosporin A (CsA) does not only exert a toxic effect on kidney parenchymal cells, but also protects them against necrotic cell death by inhibiting opening of mitochondrial permeability transition pore.... -
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- Improvement in histology, enzymatic activity, and redox state of the liver following administration of Cinnamomum zeylanicum bark oil in rats with established hepatotoxicity
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Niknezhad , Sayad-Fathi S, Karimzadeh A, Ghorbani-Anarkooli M, Yousefbeyk F, Nasiri E
- KMID: 2459546
- Anat Cell Biol.
- 2019 Sep;52(3):302-311.
- doi: 10.5115/acb.18.180
Formaldehyde (FA) is an environmentally-available pollutant. Since the liver acts as a detoxifier in the human body, it is the first and most affected organ in individuals exposed to higher-than-normal... -
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- The impact of two doses of coenzyme Q10 on semen parameters and antioxidant status in men with idiopathic oligoasthenoteratozoospermia
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Alahmar AT
- KMID: 2458498
- Clin Exp Reprod Med.
- 2019 Sep;46(3):112-118.
- doi: 10.5653/cerm.2019.00136
OBJECTIVE: Oxidative stress contributes to male infertility, and antioxidants have been recommended for treating idiopathic oligoasthenoteratozoospermia (OAT). There is, however, a lack of agreement on the type, dosing, and use... -
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- Oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome in a Nigerian tertiary hospital
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Enechukwu , Onuegbu AJ, Olisekodiaka MJ, Eleje GU, Ikechebelu JI, Ugboaja JO, Amah UK, Okwara JE, Igwegbe AO
- KMID: 2456829
- Obstet Gynecol Sci.
- 2019 Sep;62(5):335-343.
- doi: 10.5468/ogs.2019.62.5.335
OBJECTIVE: To determine the activities of oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome (PCOS) in Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria. METHODS: This was a... -
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- The effects of coenzyme Qâ‚â‚€ supplement on blood lipid indices and hepatic antioxidant defense system in SD rats fed a high cholesterol diet
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Kim HN, Jeon DG, Lim Y, Jang IS
- KMID: 2470112
- Lab Anim Res.
- 2019 Aug;35(2):86-93.
- doi: 10.1186/s42826-019-0013-1
A total of 24 SD rats were allotted to four treatment groups such as the control (CON), 1% of cholesterol diet (CHO), 0.5% of coenzyme Qâ‚â‚€ (COQ) and 1% of... -
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- Effect of Yeonsan Ogye bioactive peptides on anti-oxidant indexes in rats' liver
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Kim HW, Shim JH, Kim KN
- KMID: 2455855
- J Nutr Health.
- 2019 Aug;52(4):408-411.
- doi: 10.4163/jnh.2019.52.4.408
PURPOSE: This study investigated the effect of bioactive Yeonsan Ogye peptides (YOPs) intake on changes in the hepatic anti-oxidant indexes in male rats. METHODS: Sprague-Dawley male rats were divided into 3... -
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- 7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
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Ko YH, Kim SK, Kwon SH, Seo JY, Lee BR, Kim YJ, Hur KH, Kim SY, Lee SY, Jang CG
- KMID: 2455091
- Biomol Ther.
- 2019 Jul;27(4):363-372.
- doi: 10.4062/biomolther.2018.211
Daidzein isolated from soybean (Glycine max) has been widely studied for its antioxidant and anti-inflammatory activities. However, the protective effects of 7,8,4′-trihydroxyisoflavone (THIF), a major metabolite of daidzein, on 6-hydroxydopamine... -
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- Supplementation with psyllium seed husk reduces myocardial damage in a rat model of ischemia/reperfusion
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Lim SH, Lee J
- KMID: 2453284
- Nutr Res Pract.
- 2019 Jun;13(3):205-213.
- doi: 10.4162/nrp.2019.13.3.205
BACKGROUND/OBJECTIVES: Myocardial infarction (MI) is caused by extensive myocardial damage attributed to the occlusion of coronary arteries. Our previous study in a rat model of ischemia/reperfusion (I/R) demonstrated that administration... -
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- Effect of glycyrrhizin on nicotine-induced behavioral disturbance of planarian, Dugesia japonica
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Kim YJ, So J, Yi YJ, Lee SM
- KMID: 2452873
- J Biomed Transl Res.
- 2019 Jun;20(2):21-29.
- doi: 10.12729/jbtr.2019.20.2.021
Nicotine is a component of tobacco products and is one of the most commonly abused substances that leads to addiction. Therefore, the present study was performed to investigate the behavioral... -
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- Beta-carotene prevents the spermatogenic disorders induced by exogenous scrotal hyperthermia through modulations of oxidative stress, apoptosis, and androgen biosynthesis in mice
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Yon JM, Kim JS, Lin C, Park SG, Gwon LW, Lee JG, Baek IJ, Nahm SS, Nam SY
- KMID: 2451639
- Korean J Vet Res.
- 2019 Jun;59(2):59-67.
- doi: 10.14405/kjvr.2019.59.2.59
We investigated whether β-carotene (β-CA) or ellagic acid (EA), originating from various fruits and vegetables, has a preventive effect against male infertility induced by exogenous scrotal hyperthermia. ICR adult mice... -
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- Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress
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Kim J, Kim J, Huang Z, Goo N, Bae HJ, Jeong Y, Park HJ, Cai M, Cho K, Jung SY, Bae SK, Ryu JH
- KMID: 2447860
- Biomol Ther.
- 2019 May;27(3):327-335.
- doi: 10.4062/biomolther.2019.046
As the elderly population is increasing, Alzheimer's disease (AD) has become a global issue and many clinical trials have been conducted to evaluate treatments for AD. As these clinical trials... -
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- Antioxidant effects of kimchi supplemented with black raspberry during fermentation protect against liver cirrhosis-induced oxidative stress in rats
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Ryu EH, Yang JS, Lee MJ, Kim SH, Seo HY, Jung JH
- KMID: 2442365
- Nutr Res Pract.
- 2019 Apr;13(2):87-94.
- doi: 10.4162/nrp.2019.13.2.87
BACKGROUND/OBJECTIVES: Oxidative stress is a major effector of various diseases; accordingly, antioxidants are frequently ingested in order to prevent or alleviate disease symptoms. Kimchi contains various natural antioxidants, and it... -
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- Astaxanthin Prevents Decreases in Superoxide Dismutase 2 Level and Superoxide Dismutase Activity in Helicobacter pylori-infected Gastric Epithelial Cells
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Kim SH, Lim JW, Kim H
- KMID: 2447442
- J Cancer Prev.
- 2019 Mar;24(1):54-58.
- doi: 10.15430/JCP.2019.24.1.54
BACKGROUND: Helicobacter pylori increases production of reactive oxygen species (ROS), which activates inflammatory and carcinogenesis-related signaling pathways in gastric epithelial cells. Therefore, reducing ROS, by upregulating antioxidant enzyme, such as... -
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- A 1:1 exercise-to-rest period ratio needed by animals to restore energy sources and replenish anti-oxidative status after exercise
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Yeom MY, Cho YO
- KMID: 2434072
- Nutr Res Pract.
- 2019 Feb;13(1):17-22.
- doi: 10.4162/nrp.2019.13.1.17
BACKGROUND/OBJECTIVES: Successful recovery of an animal from exercise is essential, especially prior to the next exercise session. This study was conducted to find an effective exercise-to-rest period ratio for the... -
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