- MicroRNA-21 promotes epithelial-mesenchymal transition and migration of human bronchial epithelial cells by targeting poly (ADP-ribose) polymerase-1 and activating PI3K/AKT signaling
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Zhang S, Sun P, Xiao X, Hu Y, Qian Y, Zhang Q
- KMID: 2530943
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):239-253.
- doi: 10.4196/kjpp.2022.26.4.239
Epithelial-mesenchymal transition (EMT ) is known to be involved in airway remodeling and fibrosis of bronchial asthma. However, the molecular mechanisms leading to EMT have yet to be fully clarified.... -
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- Preventive Effect of Polysaccharide of Larimichthys crocea Swim Bladder on Reserpine Induced Gastric Ulcer in ICR Mice
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Li GJ, Sun P, Wang R, Zhou YL, Qian Y, Zhao X
- KMID: 2285509
- Korean J Physiol Pharmacol.
- 2014 Apr;18(2):183-190.
- doi: 10.4196/kjpp.2014.18.2.183
This project's aim was to determine the reserpine-induced gastric ulcer preventive effect of polysaccharide of Larimichthys crocea swim bladder (PLCSB) in ICR mice. The anti-gastric ulcer effects of polysaccharide of... -
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- D. candidum has in vitro anticancer effects in HCT-116 cancer cells and exerts in vivo anti-metastatic effects in mice
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Zhao X, Sun P, Qian Y, Suo H
- KMID: 2313768
- Nutr Res Pract.
- 2014 Oct;8(5):487-493.
- doi: 10.4162/nrp.2014.8.5.487
BACKGROUND/OBJECTIVES: D. candidum is a traditional Chinese food or medicine widely used in Asia. There has been little research into the anticancer effects of D. candidum, particularly the effects in... -
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- Baseline Serum Interleukin-6 Levels Predict the Response of Patients with Advanced Non-small Cell Lung Cancer to PD-1/PD-L1 Inhibitors
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Kang DH, Park CK, Chung C, Oh IJ, Kim YC, Park D, Kim J, Kwon GC, Kwon I, Sun P, Shin EC, Lee JE
- KMID: 2504721
- Immune Netw.
- 2020 Jun;20(3):e27.
- doi: 10.4110/in.2020.20.e27
Although various studies on predictive markers in the use of PD-1/PD-L1 inhibitors are in progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study, we... -
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- Alteration of the E-Cadherin/beta-Catenin Complex Is an Independent Poor Prognostic Factor in Lung Adenocarcinoma
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Kim H, Yoo SB, Sun P, Jin Y, Jheon S, Lee CT, Chung JH
- KMID: 1837570
- Korean J Pathol.
- 2013 Feb;47(1):44-51.
BACKGROUND: Epithelial-mesenchymal transition (EMT) is an important step in the invasion and progression of cancer and in the development of chemoresistance by cancer cells. METHODS: To address the clinical significance of... -
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- Comparison of Direct Sequencing, PNA Clamping-Real Time Polymerase Chain Reaction, and Pyrosequencing Methods for the Detection of EGFR Mutations in Non-small Cell Lung Carcinoma and the Correlation with Clinical Responses to EGFR Tyrosine Kinase Inhibitor Treatment
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Lee HJ, Xu X, Kim H, Jin Y, Sun P, Kim JE, Chung JH
- KMID: 1837571
- Korean J Pathol.
- 2013 Feb;47(1):52-60.
BACKGROUND: The aims of this study were to evaluate the abilities of direct sequencing (DS), peptide nucleic acid (PNA) clamping, and pyrosequencing methods to detect epidermal growth factor receptor (EGFR)... -
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- PCR-reverse dot blot human papillomavirus genotyping as a primary screening test for cervical cancer in a hospital-based cohort
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Kang Y, Sun P, Mao X, Dong B, Ruan G, Chen L
- KMID: 2440504
- J Gynecol Oncol.
- 2019 May;30(3):e29.
- doi: 10.3802/jgo.2019.30.e29
OBJECTIVE: To evaluate the polymerase chain reaction (PCR)-reverse-dot-blot (RDB) human papillomavirus (HPV) genotyping test as a feasible assay for the cervical cancer primary screening. METHODS: In a hospital-based cohort, a total... -
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- Clinical validation of the PCR-reverse dot blot human papillomavirus genotyping test in cervical lesions from Chinese women in the Fujian province: a hospital-based population study
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Sun P, Song Y, Ruan G, Mao X, Kang Y, Dong B, Lin F
- KMID: 2413217
- J Gynecol Oncol.
- 2017 Sep;28(5):e50.
- doi: 10.3802/jgo.2017.28.e50
OBJECTIVE: To determine the clinical significance of the polymerase chain reaction (PCR)-reverse dot blot (RDB) human papillomavirus (HPV) genotyping assay in cervical cancer screening. METHODS: A total of 10,442 women attending... -
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