- The Role of Microsatellite Instability in Development of Gastric Lymphoma
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Jung HY
- KMID: 1113460
- Korean J Gastroenterol.
- 2006 Mar;47(3):238-240.
No abstract availble. -
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- Study on Association between an H-RAS Gene Polymorphism and Gastric Cancer Development
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Oh JH
- KMID: 1775869
- Korean J Gastroenterol.
- 2010 Aug;56(2):121-122.
- doi: 10.4166/kjg.2010.56.2.121
No abstract available. -
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- What Is the Significance of Long Non-coding RNA HOX Transcript Antisense Intergenic RNA in Gastric Cancer?
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Lee SK
- KMID: 1730923
- Korean J Gastroenterol.
- 2014 Feb;63(2):137-139.
- doi: 10.4166/kjg.2014.63.2.137
No abstract available. -
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- Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms
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Kim YB, Lee SY, Kim JH, Sung IK, Park HS, Shim CS, Han HS
- KMID: 2363966
- Gut Liver.
- 2016 Mar;10(2):220-227.
- doi: 10.5009/gnl14310
BACKGROUND/AIMS: Microsatellite instability (MSI) plays a crucial role in gastrointestinal carcinogenesis. The aim of this study was to clarify whether MSI is a useful marker for predicting synchronous gastric and... -
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- Is Classification of Gastric Cancer According to Distinct Therapeutic Targets Applicable in Clinical Practice?
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Kim KM
- KMID: 1775754
- Korean J Gastroenterol.
- 2013 Aug;62(2):140-141.
- doi: 10.4166/kjg.2013.62.2.140
No abstract available. -
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- Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer
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Song IS, Wang AG, Yoon SY, Kim JM, Kim JH, Lee DS, Kim NS
- KMID: 756286
- Exp Mol Med.
- 2009 Jan;41(1):51-58.
- doi: 10.3858/emm.2009.41.1.007
Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of target genes involved in crucial aspects of cancer development. This study investigated the expression of HIFs and their contribution... -
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- Presymptomatic Identification of CDH1 Germline Mutation in a Healthy Korean Individual with Family History of Gastric Cancer
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Choi HJ, Ki CS, Suh SP, Kim JW
- KMID: 1791955
- Ann Lab Med.
- 2014 Sep;34(5):386-389.
- doi: 10.3343/alm.2014.34.5.386
Gastric cancer (GC) is one of the most common cancers with high morbidity and mortality. Familial GC is seen in 10% of cases, and approximately 3% of familial GC cases... -
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- Study on Association between Single Nucleotide Polymorphisms of MMP7, MMP8, MMP9 Genes and Development of Gastric Cancer and Lymph Node Metastasis
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Kim JH, Pyun JA, Lee KJ, Cho SW, Kwack KB
- KMID: 1026365
- Korean J Gastroenterol.
- 2011 Nov;58(5):245-251.
- doi: 10.4166/kjg.2011.58.5.245
BACKGROUND/AIMS: Matrix metallopeptidase (MMP) is known to be involved in tumor invasion and metastasis of cancer. This study investigated the association of MMP7 rs11568818, MMP8 rs11225395, MMP9 rs17576 and rs2250889... -
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- Expression of Cdx-2 Homeobox Gene in Intestinal Metaplasia and Gastric Adenocarcinoma
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Paik CH, Han DS, Lee SH, Chung YW, Kim JP, Sohn JH, Hahm JS, Oh YH, Park YU
- KMID: 1113418
- Korean J Gastroenterol.
- 2004 Oct;44(4):186-192.
BACKGROUND/AIMS: The Cdx-1 and Cdx-2 genes are intestinal transcription factors that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. The Cdx-1 and Cdx-2... -
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- Chromosomal Losses are Associated with Hypomethylation of the Gene-Control Regions in the Stomach with a Low Number of Active Genes
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Jung YC, Hong SJ, Kim YH, Kim SJ, Kang SJ, Choi SW, Rhyu MG
- KMID: 1107535
- J Korean Med Sci.
- 2008 Dec;23(6):1068-1089.
- doi: 10.3346/jkms.2008.23.6.1068
Transitional-CpG methylation between unmethylated promoters and nearby methylated retroelements plays a role in the establishment of tissue-specific transcription. This study examined whether chromosomal losses reducing the active genes in cancers... -
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- DNA Hypermethylation of Tumor-Related Genes in Gastric Carcinoma
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Hong SH, Kim HG, Chung WB, Kim EY, Lee JY, Yoon SM, Kwon JG, Sohn YK, Kwak EK, Kim JW
- KMID: 1095197
- J Korean Med Sci.
- 2005 Apr;20(2):236-241.
- doi: 10.3346/jkms.2005.20.2.236
The hypermethylation of the CpG islands is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed the methylation status of genes for cell repair... -
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- Gender-specific Association between Polymorphism of Vascular Endothelial Growth Factor (VEGF 936C>T) Gene and Patients with Stomach Cancer
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Bae SJ, Ahn DH, Hong SP, Kang H, Hwang SG, Oh D, Kim NK
- KMID: 2158197
- Yonsei Med J.
- 2008 Oct;49(5):783-791.
- doi: 10.3349/ymj.2008.49.5.783
PURPOSE: Angiogenesis plays an important role in the growth, progression, and metastasis of tumors. Vascular endothelial growth factor (VEGF) overexpression has been associated with advanced stage and poor survival in... -
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- Characterization of aberrant FHIT transcripts in gastric adenocarcinomas
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Lee SH, Kim CJ, Park HK, Koh JW, Cho MH, Baek MJ, Lee MS
- KMID: 938875
- Exp Mol Med.
- 2001 Sep;33(3):124-130.
Aberrant transcripts of FHIT (fragile histidine triad) have been reported in several types of primary tumors and cell lines, including gastric carcinoma. The role of these aberrant transcripts in tumorigenesis... -
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- Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo
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Wang XT, Xie YB, Xiao Q
- KMID: 1025167
- Exp Mol Med.
- 2011 Nov;43(11):638-645.
- doi: 10.3858/emm.2011.43.11.072
The E2F-1 transcription factor is post-translationally modified and stabilized in response to various forms of DNA damage to regulate the expression of cell-cycle and pro-apoptotic genes. The sustained overexpression of... -
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- PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells
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Hwang PH, Kim SY, Lee JC, Kim SJ, Yi HK, Lee DY
- KMID: 1089448
- Exp Mol Med.
- 2005 Oct;37(5):391-398.
PTEN/MMAC1 is a tumor suppressor gene that is mutated in a variety of advanced and metastatic cancers. Its major function is likely to be the phosphatase activity that regulates the... -
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- A Single Nucleotide Polymorphism in the E-cadherin Gene Promoter-160 is Not Associated with Risk of Korean Gastric Cancer
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Park WS, Cho YG, Park JY, Kim CJ, Lee JH, Kim HS, Lee JW, Song YH, Park CH, Park YK, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY
- KMID: 648900
- J Korean Med Sci.
- 2003 Aug;18(4):501-504.
- doi: 10.3346/jkms.2003.18.4.501
Recently, the -160 C/A polymorphism, located within the regulatory region of E-cadherin promoter, has been shown to influence E-cadherin transcription by altering transcription factor binding. We examined the effect of... -
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- The Role of Interleukin-1beta Gene Polymorphism in the Gastric Carcinogenesis
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Kang WK, Park WS, Chin HM, Park CH
- KMID: 1113294
- Korean J Gastroenterol.
- 2004 Jul;44(1):25-33.
BACKGROUND/AIMS: This study was aimed to investigate the polymorphism of interleukin-1beta(IL-1B) and IL-1 receptor antagonist (IL-1RN) gene and the relationship between genotypes and development of gastric adenocarcinoma in Korean,... -
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- Study on Association between an H-RAS Gene Polymorphism and Gastric Cancer Development
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Song HJ, Pyun JA, Lee KJ, Cho SW, Kwack KB
- KMID: 1775861
- Korean J Gastroenterol.
- 2010 Aug;56(2):78-82.
- doi: 10.4166/kjg.2010.56.2.78
BACKGROUND/AIMS: Oncogenic RAS gene mutations have been frequently observed in many tumor types, and their associations with various cancers were reported. This study was conducted to evaluate the association between... -
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- p53 protein overexpression and allele loss of p53 gene in gastric adenocarcinoma
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Choi SW, Park WS, Yang JM, Kang CS, Sun HS, Kim BS, Seo EJ, Lee MJ, Park CS
- KMID: 644812
- J Korean Med Sci.
- 1994 Aug;9(4):299-303.
- doi: 10.3346/jkms.1994.9.4.299
Gene alterations of p53 tumor suppressor gene such as point mutations, deletions or insertions occur in various human cancers. p53 protein overexpression was studied immunohistochemically in 80 gastric adenocarcinomas using... -
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- Role of TGF-beta1 and TGF-beta Type II Receptor in Gastric Cancer
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Park DI, Son HJ, Song SY, Choe WH, Lim YJ, Park SJ, Kim JJ, Kim YH, Rhee PL, Paik SW, Rhee JC, Choi KW
- KMID: 759605
- Korean J Intern Med.
- 2002 Sep;17(3):160-166.
BACKGROUND: TGF - beta is known as a cell growth inhibitory factor to suppress almost all cells, including the epithelial cell. Unlike normal cells, cancer cells are not affected... -
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