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Stereoisomerism(Chirality) of Psychotropic Drugs

Chung IW

  • KMID: 2287341
  • Korean J Psychopharmacol.
  • 2003 Mar;14(1):3-10.
Many psychotropic drugs are marketed and prescribed as a racemate form in a mixture of the stereoisomers. A chiral center or a center of unsaturation of carbon atoms in the...
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A New Stereoisomeric Monoterpene Glycoside from Clematis heracleifolia leaves

Kim MA, Yang H, Kim MJ, Chun W, Kwon Y

A new stereoisomeric monoterpene glycoside and five already-known compounds were isolated from the n-BuOH soluble fraction of Clematis heracleifolia leaves. On the basis of spectral data, the structures of the...
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Structure-antimicrobial activity relationship between pleurocidin and its enantiomer

Lee JG, Lee D

To develop novel antibiotic peptides useful as therapeutic drugs, the enantiomeric analogue of pleurocidin (Ple), which is a well known 25-mer antimicrobial peptide, was designed for proteolytic resistance by D-amino...
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Synthesis of d- and l-Form of 99mTc-HMPAO, and Comparison of Brain Uptake

Kang CS, Chang YS, Jeong JM, Lee DS, Chung JK, Lee KC, Lee MC

  • KMID: 2078736
  • Korean J Nucl Med.
  • 2001 Feb;35(1):69-74.
PURPOSE: 99mTc-HMPAO is a radiopharmaceutical for imaging cerebral blood flow. HMPAO (RR, SS)-4,8- diaza-3,6,6,9-tetramethylundecan-2,10- dione bisoxime) has three stereoismers such as, meso-, d-, and l-HMPAO. Techentium complexes of meso-HMPAO and...
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Hemodynamic Comparison between Bupivacaine and Levobupivacaine Induced Cardiovascular Collapses in Anesthetized Dogs

Jung CW, Kim JT, Choe YS, Bae SS, Kim JA, Cho HS, Lee KH

  • KMID: 2228515
  • Korean J Crit Care Med.
  • 2004 Dec;19(2):86-97.
BACKGROUND: Levobupivacaine is known to be less cardiotoxic than racemic bupivacaine but some authors have reported there were no differences in cardiotoxic profiles between two agents. We will investigate the...
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Isolation and Identification of Antifungal Compounds from Bacillus subtilis C9 Inhibiting the Growth of Plant Pathogenic Fungi

Islam MR, Jeong YT, Lee YS, Song CH

  • KMID: 2408214
  • Mycobiology.
  • 2012 Mar;40(1):59-66.
Antagonistic microorganisms against Rhizoctonia solani were isolated and their antifungal activities were investigated. Two hundred sixteen bacterial isolates were isolated from various soil samples and 19 isolates were found to...
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