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Sphingosine mediates FTY720-induced apoptosis in LLC-PK1 cells

Lee WJ, Yoo HS, Suh PG, Lim JS, Oh S, Lee YM

  • KMID: 1123763
  • Exp Mol Med.
  • 2004 Oct;36(5):420-427.
FTY720, a synthetic sphingoid base analog, was examined as a new sphingosine kinase inhibitor, which converts endogenous sphingosine into its phosphate form. With 20 micrometer of FTY720, sphingosine accumulated in...
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