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Serial CT Findings of Resolving Extramedullary Hematopoiesis as Unilateral Posterior Mediastinal Mass after Splenectomy in Hereditary Spherocytosis: A Case Report

Nam MY, Lee JW, Kim YJ, Kim YJ, Kang YH, Lee KH

Intrathoracic extramedullary hematopoiesis (EMH) is a rare condition of the hereditary spherocytosis. EMH usually regresses or disappears after treatment; such as splenectomy in the case of spherocytosis. We report a...
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Flow-Assisted Differential Diagnosis of Hemolytic Anemia with Spherocytosis: A Case Report

Won DI

In patients with hemolytic anemia associated with spherocytosis, differential diagnosis has to be made whether the hemolysis is immune-mediated or of non-immune origin. We report a case of hereditary spherocytosis...
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Prolonged Extreme Thrombocytosis in a Postsplenectomy Patient with Hereditary Spherocytosis

Park YM, Park J, Jo Y, Kim SH, Shin KC, Won IS, Sym SJ, Cho EK, Shin DB, Lee JH

We report a case of prolonged extreme reactive thrombocytosis in a post-splenectomy patient with hereditary spherocytosis. A 29-year-old female patient presented with gall stones detected incidentally by abdominal ultrasonography. Her...
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Extramedullary Hematopoiesis at the Posterior Mediastinum in Patient with Hereditary Spherocytosis: A Case Report

Yeom SY, Lim JH, Han KN, Kang CH, Park IK, Kim YT

Thoracic extramedullary hematopoiesis (EMH) is a rare disease entity that is usually associated with hematologic disorders, such as myelodysplastic or hemolytic disease. Because thoracic EMH is usually encountered as a...
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Hereditary Spherocytosis

Park ES

  • KMID: 2049272
  • Clin Pediatr Hematol Oncol.
  • 2012 Oct;19(2):57-63.
Hereditary spherocytosis is a hemolytic anemia caused by erythrocyte membrane deficiencies that lead to membrane destabilization and vesiculation. Abnormal spherocytes are trapped and destroyed in the spleen. Mutations in several...
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A Case of Hereditary Spherocytosis with Hemolytic Anemia due to Mycoplasma pneumonia

Na HY, Shin SH, Lee KM, Kim KN

  • KMID: 2278928
  • Korean J Pediatr Infect Dis.
  • 2009 Dec;16(2):215-219.
Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in children, with a peak incidence at 5-14 years. Extrapulmonary manifestations occur in 20-25% of patients with M. pneumoniae infection. Most...
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A Case of Hereditary Spherocytosis Coexisting with Gilbert's Syndrome

Lee MJ, Chang YH, Kang SH, Mun SK, Kim H, Han CJ, Kim J, Kang HJ

We recently encountered a case of hereditary spherocytosis coexisting with Gilbert's syndrome. Patient was initially diagnosed with Gilbert's syndrome and observed, but other findings suggestive of concurrent hemolysis, such as...
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Autoimmune Hemolytic Anemia after Aplastic Crisis due to Parvovirus B19 Infection in a Patient with Hereditary Spherocytosis

Song SA, Lee MY, Kim SH, Lee JY, Oh SH, Shin JH, Kim HR, Jun KR, Lee JN

  • KMID: 2312200
  • Lab Med Online.
  • 2012 Jul;2(3):166-169.
Hereditary spherocytosis (HS) is a genetic disorder characterized by the production and destruction of spherocytes due to a deficiency of red cell membrane cytoskeletal proteins, resulting in the clinical presentation...
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Hereditary Spherocytosis Coexisting with UDP-Glucuronosyltransferase Deficiency Highly Suggestive of Crigler-Najjar Syndrome Type II

Iijima S, Ohzeki T, Maruo Y

Patients with co-existing hereditary spherocytosis (HS) and UDP-glucuronosyltransferase 1A1 (UGT1A1) deficiency as Gilbert's syndrome (GS) have been reported, and previous studies have demonstrated an increased risk for developing gallstones in...
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A case of concomitant Gilbert's syndrome and hereditary spherocytosis

Lee HJ, Moon HS, Lee ES, Kim SH, Sung JK, Lee BS, Jeong HY, Lee HY, Eu YJ

We describe moderate hyperbilirubinemia in a 28-year-old man who suffered from gallstones and splenomegaly, with combined disorders of hereditary spherocytosis (HS) and Gilbert's syndrome (GS). Since it is difficult to...
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An Adult with Aplastic Crisis induced by Human Parvovirus B19 as an Initial Presentation of Hereditary Spherocytosis

Oh SE, Kim JH, Choi CH, Park KH, Jung JY, Park YI, Park MJ

The association between aplastic crisis and human parvovirus (HPV) B19 infection is well described in patients with sickle cell anemia. This association has also been described, although much less frequently,...
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Abnormalities of erythrocyte membrane proteins in Korean patients with hereditary spherocytosis

Lee YK, Cho HI, Park SS, Lee YJ, Ra E, Chang YH, Hur M, Shin HY, Ahn HS

Hereditary spherocytosis (HS) is a common inherited erythrocyte membrane disorder characterized by chronic hemolytic anemia. Clinical manifestations and biochemical abnormalities of HS are heterogeneous. In this study, we investigated erythrocyte...
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A Case of Congenital Microspherocytosis Requiring Early Splenectomy

Mong FC, Cho KS, Kim KY

Microspherocytosis is known as a hallmark of hereditary spherocytosis (HS) which is one of the most common hemolytic anemias with a prevalence of one per 5000, and is inherited...
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Hereditary Spherocytosis in Children: Experiences in a Single Center

Park EA, Kim MK, Park JK, Lee SY

  • KMID: 2168941
  • Clin Pediatr Hematol Oncol.
  • 2010 Oct;17(2):137-146.
PURPOSE: The aim of this study was to evaluate the clinical and laboratory findings of hereditary spherocytosis (HS) by comparing patients of different age groups and profiling the outcomes of...
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Splenic infarction in a patient with autoimmune hemolytic anemia and protein C deficiency

Park MY, Kim JA, Yi SY, Chang SH, Um TH, Lee HR

Splenic infarction is most commonly caused by cardiovascular thromboembolism; however, splenic infarction can also occur in hematologic diseases, including sickle cell disease, hereditary spherocytosis, chronic myeloproliferative disease, leukemia, and lymphoma....
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Hereditary hemolytic anemia in Korea from 2007 to 2011: A study by the Korean Hereditary Hemolytic Anemia Working Party of the Korean Society of Hematology

Park ES, Jung HL, Kim HJ, Park SS, Bae SH, Shin HY, Song SH, Koh KN, Lyu CJ, Lim YT, Han DK, Hah JO

BACKGROUND: The number of patients diagnosed with hereditary hemolytic anemia (HHA) has increased since the advent of novel diagnostic techniques that accurately identify this disorder. Here, we report data from...
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Clinical Experiences of Laparoscopic Surgery in Children

Hong YI, Park JH, Kim IS, Rhee JA, Kim SY

  • KMID: 2004073
  • J Korean Surg Soc.
  • 2008 Jul;75(1):47-55.
PURPOSE: The indications for pediatric laparoscopic surgery are increasing according to the improvement of laparoscopic procedures and instruments and the increased knowledge of its safety and benefits. We summarized the...
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