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Serum IgE specific to egg white and its components and open baked egg oral food challenge tests in children younger than 6 years

Song KB, Yang SI, Jung S, Hwang KH, Kim MJ, Yoon J, Yu J

Purpose: Sixty to eighty percent of children with egg allergy are able to tolerate eggs in baked form. The purpose of this study was to evaluate the clinical usefulness and...
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Current Update of Local Allergic Rhinitis

Kim SJ, Moon JW, Lee HM

Local allergic rhinitis (LAR) is a localized nasal allergic response in the absence of systemic atopy. The symptoms, duration, severity, and comorbidities of LAR are similar to those of allergic...
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Anti-allergic Effect of Fructus amomi on Ovalbumin-induced Asthma Mice Model

Piao CH, Fan YJ, Nguyen TV, Yu ZN, Shin HS, Song CH, Chai OH

Despite studies on the anti-inflammatory effect of Fructus amomi, mature fruit of Amomum villosum Lour, have been getting increasing extensively, it remains unknown about the detailed effects of F. amomi...
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Trends of Sensitization to Inhalant Allergens in Korean Children Over the Last 10 Years

Kim YJ, Lee MY, Yang AR, Sol IS, Kwak JH, Jung HL, Shim JW, Kim DS, Shim JY

Purpose: Climate and lifestyle changes increase an individual’s susceptibility to various allergens and also the incidence of allergic diseases. We aimed to examine the changes in sensitization rate for aeroallergens...
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Clinical and Laboratory Findings of Barley Allergy in Korean Children: a Single Hospital Based Retrospective Study

Lee E, Jeong K, Lee J, Jeon SA, Park B, Lee H, Lee S

BACKGROUND: Barley is a grain that is consumed in various forms in Asia. Studies on barley allergy are limited to a few case reports about hypersensitivity reactions to beer, but...
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Proper Cut-off Levels of Serum Specific IgE to Cefaclor for Patients with Cefaclor Allergy

Nam YH, Lee SH, Rhyou HI, Lee YS, Park SH, Lee YH, Shin YS, Park HS, Ye YM

PURPOSE: Cefaclor, a second-generation oral cephalosporin, is known to cause IgE-mediated hypersensitivity. Assays of serum-specific IgE (sIgE) to cefaclor are commercially available via the ImmunoCAP system (Thermo Fisher Scientific). While...
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Clinical characteristics of total IgE in pediatric allergic disease

Ahn JY, Choi BS

PURPOSE: Serum total and specific IgE levels have been widely used to diagnose allergic disease. However, it has recently been suggested that serum total IgE does not properly reflect specific...
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Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation and mast cell-mediated anaphylactic shock by regulation of Th1/Th2 imbalance and histamine release

Bui TT, Piao CH, Song CH, Lee CH, Shin HS, Chai OH

Asthma is characterized by chronic inflammation, goblet cell hyperplasia, the aberrant production of the Th2 cytokines, and eosinophil infiltration into the lungs. In this study, we examined the effects of...
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Involvement of cross-reactive carbohydrate determinants-specific IgE in pollen allergy testing

Yokoi H, Yoshitake , Matsumoto , Kawada M, Takato Y, Shinagawa , Sakurai H, Saito K

BACKGROUND: Specific IgE antibodies against the low-molecular-weight carbohydrate antigen that does not bridge IgE molecules on mast cells are not associated with clinical symptoms. Cross reactivity can be determined in...
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Different Responses in Induction of Allergen Specific Immunoglobulin G4 and IgE-Blocking Factors for Three Mite Subcutaneous Immunotherapy Products

Park KH, Lee SC, Son YW, Jeong KY, Shin YS, Shin JU, Sim DW, Park HJ, Lee JH, Lee KH, Park JW

PURPOSE: Specific immunoglobulin G4 (sIgG4) and immunoglobulin E (IgE)-blocking factors produced by subcutaneous immunotherapy (SCIT) play a critical role in the induction of allergen tolerance. However, comparative studies of available...
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Diagnostic Value of Specific IgE to Peanut and Ara h 2 in Korean Children with Peanut Allergy

Kim HY, Han Y, Kim K, Lee JY, Kim MJ, Ahn K, Kim J

PURPOSE: The purpose of this study was to establish the diagnostic decision point (DDP) of peanut specific IgE (sIgE) for predicting the outcome of oral food challenge (OFC). We also...
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Comparison of Component-Resolved Diagnosis by Using Allergen Microarray With the Conventional Tests in Allergic Rhinitis Patients: The First Using in Korea

Jung JH, Kang IG, Kim ST

OBJECTIVES: The aim of this study was to evaluate the component-resolved diagnosis using a microarray allergen chip (Immuno Solid-phase Allergen Chip, ImmunoCAP ISAC) and to compare this new diagnostic tool...
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Performance of the PROTIA(TM) Allergy-Q(R) System in the Detection of Allergen-specific IgE: A Comparison With the ImmunoCAP(R) System

Lee JH, Park HJ, Park KH, Jeong KY, Park JW

PURPOSE: The PROTIA(TM) Allergy-Q(R) enzyme immunoassay (EIA) is a recently developed screening assay for specific immunoglobulin E (sIgE) for multiple allergens. The ImmunoCAP(R) fluorescent EIA (FEIA) system is the most...
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Diagnostic Decision Points of Specific IgE Concentrations in Korean Children With Egg and Cow's Milk Allergies

Kim J, Kim HY, Park MR, Choi J, Shim JY, Kim MJ, Han Y, Ahn K

PURPOSE: The purpose of this study was to evaluate the utility of specific IgE (sIgE) concentrations for the diagnosis of immediate-type egg and cow's milk (CM) allergies in Korean children...
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Comparison of MAST-CLA System Results and Allergen Detection Rates between Acute and Chronic Urticaria Patients in Gangwon, Yeongseo Province, Korea

Chung HC, Ahn SK

  • KMID: 2246085
  • Korean J Dermatol.
  • 2015 Jun;53(5):374-380.
BACKGROUND: The multiple allergosorbent test chemiluminescent assay (MAST-CLA) is a simple system with high sensitivity and specificity for measuring total and allergen-specific IgE antibodies in patients with allergic skin diseases...
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Immunologic Evaluation of Patients with Cefotetan-Induced Anaphylaxis

Nam YH, Hwang EK, Ban GY, Jin HJ, Yoo HS, Shin YS, Ye YM, Nahm DH, Park HS, Lee SK

Cefotetan is a commonly prescribed second-generation cephalosporin that acts against a wide range of bacteria. However, cefotetan-induced hypersensitivity has rarely been reported. We report 2 cases of cefotetan-induced anaphylaxis with...
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Anaphylaxis following mushrooms ingestion

Seo DH, Lee YS, Ban GY, Yoon MG, Kim JH, Shin YS, Park HS, Ye YM

Various foods can induce anaphylaxis. However, mushrooms-induced anaphylaxis has not been reported in Korea. We report a patient with past anaphylactic episode caused by mushroom ingestion, confirmed by the skin...
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Prevalence of serum allergen-specific immunoglobulin E for canine atopic dermatitis in Korea

Jang HM, Yeo GS, Kim JH, Hwang CY, Hyun JE, Kim SS, Kang YH, Jung DI

Canine atopic dermatitis (CAD) is an allergic skin disease with characteristic clinical features associated with immunoglobulin E (IgE) antibodies. Identification of the causative allergens is the diagnostic goal, which is...
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Clinical features of elderly chronic urticaria

Ban GY, Kim MY, Yoo HS, Nahm DH, Ye YM, Shin YS, Park HS

BACKGROUND/AIMS: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this...
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Comparison of MAST-CLA System Results between Children and Adults with Atopic Dermatitis (2005~2012, Gangwon, Yeongseo Province)

Lee NR, Ahn SK

  • KMID: 1734186
  • Korean J Dermatol.
  • 2014 Nov;52(11):769-775.
BACKGROUND: The multiple allergosorbent test chemiluminescent assay (MAST-CLA) system is a simple method with high sensitivity and specificity for measuring total and allergen-specific IgE antibodies in patients with allergic skin...
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