- Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice
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Yun WB, Kim JE, Lee ML, Choi JY, Park JJ, Song BR, Kang BC, Nam KT, Lee HW, Hwang DY
- KMID: 2523774
- Lab Anim Res.
- 2021 Dec;37(4):294-306.
- doi: 10.1186/s42826-021-00107-y
Background: This study was undertaken to compare the sensitivities of mice strains during tumor induction by transcription activator-like effector nucleases (TALEN)-mediated Trp53 mutant gene. Alterations of their tumorigenic phenotypes including... -
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- Inhibition of endoplasmic reticulum stress in high-fat-diet-induced obese C57BL/6 mice: Efficacy of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris
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Lee MR, Bae SJ, Kim JE, Song BR, Choi JY, Park JJ, Park JW, Kang MJ, Choi HJ, Choi YW, Kim KM, Hwang DY
- KMID: 2459307
- Lab Anim Res.
- 2018 Dec;34(4):288-294.
- doi: 10.5625/lar.2018.34.4.288
A few clues about correlation between endoplasmic reticulum (ER) stress and mulberry (Morus alba) leaves were investigated in only the experimental autoimmune myocarditis and streptozotocin-induced diabetes. To investigate whether a... -
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- Regulation of gastrointestinal hormones during laxative activity of gallotannin-enriched extract isolated from Galla Rhois in loperamide-induced constipation of SD rats
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Kim JE, Kang MJ, Choi JY, Park JJ, Lee MR, Song BR, Kim HR, Park JW, Choi HJ, Bae SJ, Hwang DY
- KMID: 2459299
- Lab Anim Res.
- 2018 Dec;34(4):223-231.
- doi: 10.5625/lar.2018.34.4.223
Regulation of gastrointestinal hormones have been reported in animal models for constipation undergoing laxative therapy when administered herbal products. We undertook to investigate whether the laxative activity of gallotannin-enriched extracts... -
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- Management of Elderly Diabetes Patients Who Are Unable to Self-Care
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Song BR
- KMID: 2442362
- J Korean Diabetes.
- 2018 Dec;19(4):232-236.
- doi: 10.4093/jkd.2018.19.4.232
Modern medical advances have led to an aging society with longer life expectancy, and now the health awareness of the elderly is increasing, presuming an average age of 100 years.... -
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- Successful development of squamous cell carcinoma and hyperplasia in RGEN-mediated p27 KO mice after the treatment of DMBA and TPA
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Choi JY, Yun WB, Kim JE, Lee MR, Park JJ, Song BR, Kim HR, Park JW, Kang MJ, Kang BC, Lee HW, Hwang DY
- KMID: 2420824
- Lab Anim Res.
- 2018 Sep;34(3):118-125.
- doi: 10.5625/lar.2018.34.3.118
To evaluate the carcinogenicity of p27 knockout (KO) mice with RNA-guided endonuclease (RGENs)-mediated p27 mutant exon I gene (IΔ), alterations in the carcinogenic phenotypes including tumor spectrum, tumor suppressor proteins,... -
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- Dose dependence and durability of the therapeutic effects of Asparagus cochinchinensis fermented extract in an ovalbumin-challenged asthma model
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Choi JY, Park JW, Kim JE, Park JJ, Lee MR, Song BR, Kang MJ, Hwang DY
- KMID: 2420822
- Lab Anim Res.
- 2018 Sep;34(3):101-110.
- doi: 10.5625/lar.2018.34.3.101
The butanol extract of Asparagus cochinchinensis roots fermented with Weissella cibaria (BAfW) significantly suppressed the inflammatory response induced by lipopolysaccharide (LPS) treatment in RAW264.7 cells. To investigate the dose dependence... -
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- Goal Attainment Rate for Parameters of Metabolic Adjustment in Elderly Patients with Type 2 Diabetes Taking a Hypoglycemic Agent
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Shim KH, Hwang MS, Park JE, Jung JH, Lee JH, Song BR
- KMID: 2408660
- J Korean Diabetes.
- 2018 Mar;19(1):58-70.
- doi: 10.4093/jkd.2018.19.1.58
BACKGROUND: This study aimed to investigate the goal attainment rates for hemoglobin A1c (HbA1c), blood pressure (BP), and low-density lipoprotein cholesterol (LDL-C) in elderly patients with type 2 diabetes. METHODS: The... -
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- Erratum: Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources
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Yun WB, Kim HR, Kim JE, Choi JY, Lee MR, Park JJ, Song BR, Jung YS, Song HK, Cho JY, Kim KS, Hwang DY
- KMID: 2402274
- Lab Anim Res.
- 2017 Dec;33(4):321-321.
- doi: 10.5625/lar.2017.33.4.321
One of the authors' names was misprinted. -
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- Correlation between laxative effects of uridine and suppression of ER stress in loperamide induced constipated SD rats
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Kim JE, Song BR, Yun WB, Choi JY, Park JJ, Lee MR, Hwang DY
- KMID: 2402266
- Lab Anim Res.
- 2017 Dec;33(4):298-307.
- doi: 10.5625/lar.2017.33.4.298
A correlation between endoplasmic reticulum (ER) stress and laxative effects was first reported in a constipation model treated with an aqueous extract of Liriope platyphylla (AEtLP) roots. To investigate the... -
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- Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats
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Lee MR, Kim JE, Yun WB, Choi JY, Park JJ, Kim HR, Song BR, Choi YW, Kim KM, Hwang DY
- KMID: 2391102
- Lab Anim Res.
- 2017 Sep;33(3):270-279.
- doi: 10.5625/lar.2017.33.3.270
Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the... -
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- Comparison of therapeutic responses to an anticancer drug in three stocks of ICR mice derived from three different sources
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Sung JE, Kim JE, Lee HA, Yun WB, Choi JY, Lee MR, Park JJ, Kim HR, Song BR, Jung YS, Kim KS, Hwang DY
- KMID: 2407434
- Lab Anim Res.
- 2017 Jun;33(2):187-194.
- doi: 10.5625/lar.2017.33.2.187
Korl:ICR mice, established by the Korean National Institute of Food and Drug Safety Evaluation (NIFDS), are characterized based on their genetic variation, response to gastric injury, and response to constipation... -
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- Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources
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Yun WB, Kim HR, Kim JE, Choi JY, Lee MR, Park JJ, Song BR, Jung YS, Song HK, Cho JY, Kim KS, Hwang DY
- KMID: 2407433
- Lab Anim Res.
- 2017 Jun;33(2):179-186.
- doi: 10.5625/lar.2017.33.2.179
C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neurobiology, and... -
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- Hepatotoxicity and nephrotoxicity of saponin-enriched extract of Asparagus cochinchinensis in ICR mice
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Sung JE, Choi JY, Kim JE, Lee HA, Yun WB, Park JJ, Kim HR, Song BR, Kim DS, Lee CY, Lee HS, Lim Y, Hwang DY
- KMID: 2407417
- Lab Anim Res.
- 2017 Jun;33(2):57-67.
- doi: 10.5625/lar.2017.33.2.57
The inhibitory effects of Asparagus cochinchinensis against inflammatory response induced by lipopolysaccharide (LPS), substance P and phthalic anhydride (PA) treatment were recently reported for some cell lines and animal models.... -
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- Current Status of Management in Type 2 Diabetes Mellitus at General Hospitals in South Korea
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Jung JH, Lee JH, Noh JW, Park JE, Kim HS, Yoo JW, Song BR, Lee JR, Hong MH, Jang HM, Na Y, Lee HJ, Lee JM, Kang YG, Kim SY, Sim KH
- KMID: 2174026
- Diabetes Metab J.
- 2015 Aug;39(4):307-315.
- doi: 10.4093/dmj.2015.39.4.307
BACKGROUND: In Korea, the prevalence, complications, and mortality rate of diabetes are rapidly increasing. However, investigations on the actual condition of diabetes management are very limited due to lack of... -
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- Establishment of Blood Glucose Monitoring System using Internet
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Kim HS, Cho JH, Kwon HS, Lee JH, Song BR, Oh JA, Yoon KH, Son HY
- KMID: 1768007
- J Korean Diabetes Assoc.
- 2003 Jun;27(3):280-287.
BACKGROUND: The internet has been used world wide as a communication tool. To improve the quality of glucose control, the effectiveness of an Internet-based Blood Glucose Monitoring System (IBGMS), on... -
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- Morphology and Distribution of Motor Neurons in Cat Innervating the Orbicularis Oculi Muscle by Retrograde Horseradish Peroxidase
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Lee KY, Yoo JH, Song BR
- KMID: 2127738
- J Korean Ophthalmol Soc.
- 2000 Oct;41(10):2099-2106.
The facial nerve is mainly composed of motor fibers and is distributed to the muscles of facial expressions. In ophthalmology clinics, orbicularis oculi muscle innervated by the facial nerve is... -
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- A Case of Oculocutaneous Albinism
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Lee KY, Ban MS, Song BR, Yoo JH
- KMID: 2147609
- J Korean Ophthalmol Soc.
- 2000 Jan;41(1):288-293.
Oculocutaneous albinism resulting from genetic defect of melanin synthesizing system is characterized by pale skin, straw-colored hair, hypopigmentation of the iris, hypoplasia of fovea, photophobia, low visual acuity and strabismus.... -
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- The Lysozymal Concentration in Tear Film of Contact Lens Us ers
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Song BR, Kim DK, Byon DS
- KMID: 2147571
- J Korean Ophthalmol Soc.
- 2000 Jan;41(1):12-17.
The contact lens wearers are exposed to the risk of permanent visual dysfunction due to various ocular diseases, especially corneal infections. And ocular disease of contact lens wearers are reported... -
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- The Comparison of Tear-Specific Prealbumin in Diabetc Patients with Normal Subjects
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Cho JK, Song BR, Yoo JH, Chang JS, Byon DS
- KMID: 2205627
- J Korean Ophthalmol Soc.
- 1999 Nov;40(11):2955-2960.
Human tear proteins serve many roles to maintain the health and intergrity of the preocular tear film and ocular surface environment. The proportion of tear proteins can be changed markedly... -
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- The Concentration of Tear Lysozyme in Normal Subjects and Dry Eye
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Kim DK, Song BR
- KMID: 2205591
- J Korean Ophthalmol Soc.
- 1999 Oct;40(10):2693-2700.
The compositional change of ocular tear film in dry eyes can induce the various ocular surface diseases. It is reported that the pathophysiology of dry eye is directly related to... -
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