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In Vitro Modeling of the Tumor Microenvironment in Tumor Organoids

Devarasetty M, Forsythe SD, Shelkey E, Soker S

BACKGROUND: The tumor microenvironment (TME) represents the many components occupying the space within and surrounding a tumor, including cells, signaling factors, extracellular matrix, and vasculature. Each component has the potential...
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Differentiation of Human Dental Pulp Stem Cells into Dopaminergic Neuron-like Cells in Vitro

Chun SY, Soker S, Jang YJ, Kwon TG, Yoo ES

We investigated the potential of human dental pulp stem cells (hDPSCs) to differentiate into dopaminergic neurons in vitro as an autologous stem cell source for Parkinson's disease treatment. The hDPSCs...
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