- Echinostoma macrorchis Metacercariae in Cipangopaludina chinensis malleata from Xiengkhuang Province, Lao PDR and Morphologies of Adults from Experimental Animals
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Sohn WM, Na BK, Lee D, Eom KS, Yong TS, Chai JY, Min DY
- KMID: 2469999
- Korean J Parasitol.
- 2019 Dec;57(6):657-664.
- doi: 10.3347/kjp.2019.57.6.657
We identified the echinostome metacercariae in Chinese mystery snails, Cipangopaludina chinensis malleata, from Xiengkhuang Province, Lao PDR with morphologies of adult worms recovered. Total 20 snails were examined with artificial... -
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- Differential Change in the Prevalence of the Ascaris, Trichuris and Clonorchis infection Among Past East Asian Populations
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Zhan X, Yeh HY, Shin DH, Chai JY, Seo M, Mitchell P
- KMID: 2469991
- Korean J Parasitol.
- 2019 Dec;57(6):601-605.
- doi: 10.3347/kjp.2019.57.6.601
As we learn more about parasites in ancient civilizations, data becomes available that can be used to see how infection may change over time. The aim of this study is... -
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- Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
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Kang SH, Kim SW, Kim KJ, Cho KH, Park JW, Kim CD, Do JY
- KMID: 2469377
- Kidney Res Clin Pract.
- 2019 Dec;38(4):472-480.
- doi: 10.23876/j.krcp.19.049
BACKGROUND: We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs). METHODS: We performed in... -
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- p90RSK Activation Promotes Epithelial-Mesenchymal Transition in Cisplatin-Treated Triple-Negative Breast Cancer Cells
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Jin Y, Heo KS
- KMID: 2468028
- J Bacteriol Virol.
- 2019 Dec;49(4):221-229.
- doi: 10.4167/jbv.2019.49.4.221
p90 ribosomal S6 kinase (p90RSK), one of the downstream effectors in ERK1/2 pathways, shows high expression in human breast cancer tissues. However, its role in breast cancer development and drug... -
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- Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells
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Zhu SM, Park YR, Seo SY, Kim IH, Lee ST, Kim SW
- KMID: 2465818
- Intest Res.
- 2019 Oct;17(4):527-536.
- doi: 10.5217/ir.2019.00031
BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide... -
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- BRCA1 and Breast Cancer: a Review of the Underlying Mechanisms Resulting in the Tissue-Specific Tumorigenesis in Mutation Carriers
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Semmler L, Reiter-Brennan C, Klein A
- KMID: 2441847
- J Breast Cancer.
- 2019 Mar;22(1):1-14.
- doi: 10.4048/jbc.2019.22.e6
Since the first cloning of BRCA1 in 1994, many of its cellular interactions have been elucidated. However, its highly specific role in tumorigenesis in the breast tissue—carriers of BRCA1 mutations... -
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- Freshwater snails as the intermediate host of trematodes in Iran: a systematic review
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Dodangeh S, Daryani A, Sharif M, Gholami S, Kialashaki E, Moosazadeh M, Sarvi S
- KMID: 2469404
- Epidemiol Health.
- 2019;41:e2019001.
- doi: 10.4178/epih.e2019001
Freshwater snails, as the first intermediate hosts of trematodes, can cause health hazards in animals and humans. Recently, the World Health Organization has included Iran in a list of 6... -
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- Extracellular acidity enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via DR5 in gastric cancer cells
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Hong R, Han SI
- KMID: 2419001
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):513-523.
- doi: 10.4196/kjpp.2018.22.5.513
The tumor microenvironment greatly influences cancer cell characteristics, and acidic extracellular pH has been implicated as an essential factor in tumor malignancy and the induction of drug resistance. Here, we... -
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- MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line
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Wang L, Qu J, Zhou L, Liao F, Wang J
- KMID: 2417882
- Cancer Res Treat.
- 2018 Jul;50(3):936-949.
- doi: 10.4143/crt.2017.302
PURPOSE: The purpose of this study was to investigate the biological role and mechanism of miR-373 targeting of TFIIB-related factor 2 (BRF2) in the regulation of non-small cell lung cancer... -
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- Participation of CCL1 in Snail-Positive Fibroblasts in Colorectal Cancer Contribute to 5-Fluorouracil/Paclitaxel Chemoresistance
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Li Z, Chan K, Qi Y, Lu L, Ning F, Wu M, Wang H, Wang Y, Cai S, Du J
- KMID: 2417878
- Cancer Res Treat.
- 2018 Jul;50(3):894-907.
- doi: 10.4143/crt.2017.356
PURPOSE: Cancer-associated fibroblasts (CAFs) activated by cancer cells has a central role in development and malignant biological behavior in colorectal cancer (CRC). Adult fibroblasts do not express Snail, but Snail-positive... -
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- Luteolin Induces Apoptosis via Mitochondrial Pathway and Inhibits Invasion and Migration of Oral Squamous Cell Carcinoma by Suppressing Epithelial-Mesenchymal Transition Induced Transcription Factors
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Park BS, Kil JJ, Kang HM, Yu SB, Park DB, Park JA, Kim IR
- KMID: 2437357
- Int J Oral Biol.
- 2018 Jun;43(2):69-76.
- doi: 10.11620/IJOB.2018.43.2.069
Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy. Numerous therapies have been proposed for its cure. Research is continually being conducted to develop new forms... -
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- Freshwater Snail Diversity in Mae Lao Agricultural Basin (Chiang Rai, Thailand) with a Focus on Larval Trematode Infections
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Chantima K, Suk-ueng K, Kampan M
- KMID: 2416355
- Korean J Parasitol.
- 2018 Jun;56(3):247-257.
- doi: 10.3347/kjp.2018.56.3.247
The aim of this study was to conduct a freshwater snail survey in Mae Lao agricultural basin to assess the diversity with a focus on habitat types and their larval... -
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- New Record of Thapariella anastomusa (Trematoda: Thapariellidae) Metacercariae in Northern Thailand
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Phalee W, Phalee A, Wongsawad
- KMID: 2408524
- Korean J Parasitol.
- 2018 Feb;56(1):49-52.
- doi: 10.3347/kjp.2018.56.1.49
The family Thapariellidae has been reported in only 3 countries since 1990. The objective of this study was to identify Thapariella anastomusa metacercariae in snails in Thailand based on morphological... -
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- Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin
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Jeong BY, Cho KH, Jeong KJ, Park YY, Kim JM, Rha SY, Park CG, Mills GB, Cheong JH, Lee HY
- KMID: 2438365
- Exp Mol Med.
- 2018 Jan;50(1):e435.
- doi: 10.1038/emm.2017.248
The small GTP-binding protein Rab25 is associated with tumor formation and progression. However, recent studies have shown discordant effects of Rab25 on cancer cell progression depending on cell lineage. In... -
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- T-cell immune regulator 1 enhances metastasis in hepatocellular carcinoma
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Yang HD, Eun JW, Lee KB, Shen Q, Kim HS, Kim SY, Seo DW, Park WS, Lee JY, Nam SW
- KMID: 2438350
- Exp Mol Med.
- 2018 Jan;50(1):e420.
- doi: 10.1038/emm.2017.166
Recurrence and metastasis are major challenges in the management of hepatocellular carcinoma (HCC) patients after resection. To identify a metastasis-associated gene signature, we performed comparative gene expression analysis with recurrent... -
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- The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy
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Cho ES, Cha YH, Kim HS, Kim NH, Yook JI
- KMID: 2400812
- Biomol Ther.
- 2018 Jan;26(1):29-38.
- doi: 10.4062/biomolther.2017.179
During cancer progression, cancer cells are repeatedly exposed to metabolic stress conditions in a resource-limited environment which they must escape. Increasing evidence indicates the importance of nicotinamide adenine dinucleotide phosphate... -
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- Echinostoma macrorchis (Digenea: Echinostomatidae): Metacercariae in Cipangopaludina chinensis malleata Snails and Adults from Experimental Rats in Korea
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Sohn WM, Na BK
- KMID: 2395758
- Korean J Parasitol.
- 2017 Oct;55(5):541-548.
- doi: 10.3347/kjp.2017.55.5.541
A survey was performed to know the infection status of echinostome metacercariae in Cipangopaludina chinensis malleata snails from Korea. Total 75 snails collected in 5 localities, i.e., Imsil-gun, Jeollabuk-do, Hwasun-gun... -
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- Inhibition of microRNA-214 promotes epithelial–mesenchymal transition process and induces interstitial cystitis in postmenopausal women by upregulating Mfn2
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Lv JW, Wen W, Jiang C, Fu QB, Gu YJ, Lv TT, Li ZD, Xue W
- KMID: 2388355
- Exp Mol Med.
- 2017 Jul;49(7):e357.
- doi: 10.1038/emm.2017.98
Our study aims to investigate the roles that microRNA-214 (miR-214) plays in the epithelial mesenchymal transition (EMT) process and the development of interstitial cystitis (IC) in postmenopausal women by targeting... -
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- Long Non-coding RNA HOXA11 Antisense Promotes Cell Proliferation and Invasion and Predicts Patient Prognosis in Serous Ovarian Cancer
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Yim GW, Kim HJ, Kim LK, Kim SW, Kim S, Nam EJ, Kim YT
- KMID: 2388311
- Cancer Res Treat.
- 2017 Jul;49(3):656-668.
- doi: 10.4143/crt.2016.263
PURPOSE: The biological function of long non-coding RNAs (lncRNAs) is only partially understood; therefore, in this study, we investigated the expression of the novel HOXA11 antisense (HOXA11as) lncRNA and its... -
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- The role of hypoxia on the acquisition of epithelial-mesenchymal transition and cancer stemness: a possible link to epigenetic regulation
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Yeo CD, Kang N, Choi SY, Kim BN, Park CK, Kim JW, Kim YK, Kim SJ
- KMID: 2387703
- Korean J Intern Med.
- 2017 Jul;32(4):589-599.
- doi: 10.3904/kjim.2016.302
A hypoxic microenvironment leads to cancer progression and increases the metastatic potential of cancer cells within tumors via epithelial-mesenchymal transition (EMT) and cancer stemness acquisition. The hypoxic response pathway can... -
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