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Chronic Obstructive Pulmonary Disease and the Airway Microbiome: What Respirologists Need to Know

Sin DD

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. The lower airways contain a rich and diverse microbiome, which may play a significant regulatory role...
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Asthma-COPD Overlap Syndrome: What We Know and What We Don't

Sin DD

Approximately one in four patients with chronic obstructive pulmonary disease (COPD) have asthmatic features consisting of wheezing, airway hyper-responsiveness or atopy. The Global initiative for Asthma/Globalinitiative for chronic Obstructive Lung...
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The Importance of Early Chronic Obstructive Pulmonary Disease: A Lecture from 2022 Asian Pacific Society of Respirology

Sin DD

Chronic obstructive pulmonary disease (COPD) affects close to 400 million people worldwide. COPD is characterized by significant airflow limitation on spirometry. Most patients with COPD are diagnosed in their fifth...
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The Role of Granzyme B Containing Cells in the Progression of Chronic Obstructive Pulmonary Disease

Kim WD, Chi HS, Choe KH, Kim WS, Hogg JC, Sin DD

Background: Lung inflammation plays a vital role in the pathogenesis of chronic obstructive pulmonary disease (COPD), but the characteristics of the inflammatory process remain unclear. There is growing interest in...
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