- Use of Solid Boluses in High-resolution Manometry
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Wang YT, Sifrim D
- KMID: 2325761
- J Neurogastroenterol Motil.
- 2013 Oct;19(4):422-423.
No abstract available. -
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- Deglutitive Inhibition, Latency Between Swallow and Esophageal Contractions and Primary Esophageal Motor Disorders
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Sifrim D, Jafari J
- KMID: 2325855
- J Neurogastroenterol Motil.
- 2012 Jan;18(1):6-12.
Swallowing induces an inhibitory wave that is followed by a contractile wave along the esophageal body. Deglutitive inhibition in the skeletal muscle of the esophagus is controlled in the brain... -
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- The Role of Weakly Acidic Reflux in Proton Pump Inhibitor Failure, Has Dust Settled?
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Tsoukali E, Sifrim D
- KMID: 2326159
- J Neurogastroenterol Motil.
- 2010 Jul;16(3):258-264.
Patients that do not respond satisfactorily to standard proton pump inhibitor (PPI) treatment have become the most common presentation of gastro-esophageal reflux disease (GERD) in third referral gastrointestinal practices. The... -
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- Supragastric Belching: Prevalence and Association With Gastroesophageal Reflux Disease and Esophageal Hypomotility
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Koukias N, Woodland P, Yazaki E, Sifrim D
- KMID: 2433479
- J Neurogastroenterol Motil.
- 2015 Jul;21(3):398-403.
- doi: 10.5056/jnm15002
BACKGROUND/AIMS: Supragastric belching (SGB) is a phenomenon during which air is sucked into the esophagus and then rapidly expelled through the mouth. Patients often complain of severely impaired quality of... -
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- High-resolution Manometry: Esophageal Disorders Not Addressed by the "Chicago Classification"
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Wang YT, Yazaki E, Sifrim D
- KMID: 2325945
- J Neurogastroenterol Motil.
- 2012 Oct;18(4):365-372.
The development of the high-resolution esophageal manometry (HRM) and the Chicago classification have improved the diagnosis and management of esophageal motility disorders. However, some conditions have yet to be addressed... -
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- Nocturnal Gastroesophageal Reflux Revisited by Impedance-pH Monitoring
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Fornari F, Blondeau K, Mertens V, Tack J, Sifrim D
- KMID: 2326208
- J Neurogastroenterol Motil.
- 2011 Apr;17(2):148-157.
BACKGROUND/AIMS: Impedance-pH monitoring allows detailed characterization of gastroesophageal reflux and esophageal activity associated with reflux. We assessed the characteristics of nocturnal reflux and esophageal activity preceding and following reflux. METHODS: Impedance-pH... -
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- Measurement of Esophageal Nocturnal Baseline Impedance: A Simplified Method
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Hoshikawa , Sawada A, Sonmez S, Nikaki K, Woodland P, Yazaki E, Sifrim D
- KMID: 2500681
- J Neurogastroenterol Motil.
- 2020 Apr;26(2):.
- doi: 10.5056/jnm19183
Background/Aims Mean nocturnal baseline impedance (MNBI) during multichannel intraluminal impedance pH-monitoring (MII-pH) reflects the status of esophageal mucosal integrity. MNBI is suggested as an adjunctive method to distinguish patients with... -
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- 200 mL Rapid Drink Challenge During High-resolution Manometry Best Predicts Objective Esophagogastric Junction Obstruction and Correlates With Symptom Severity
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Woodland P, Gabieta-Sonmez S, Arguero J, Ooi J, Nakagawa K, Glasinovic E, Yazaki E, Sifrim D
- KMID: 2417385
- J Neurogastroenterol Motil.
- 2018 Jul;24(3):410-414.
- doi: 10.5056/jnm18038
BACKGROUND/AIMS: Single swallow integrated relaxation pressure (IRP) on high-resolution manometry (HRM) does not always accurately predict esophagogastric outflow obstruction on timed barium esophagogram (TBE). Furthermore, neither single swallow IRP or... -
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- Relationship Between Salivary Pepsin Concentration and Esophageal Mucosal Integrity in Patients With Gastroesophageal Reflux Disease
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Li YW, Sifrim D, Xie C, Chen M, Xiao YL
- KMID: 2395419
- J Neurogastroenterol Motil.
- 2017 Oct;23(4):517-525.
- doi: 10.5056/jnm16178
BACKGROUND/AIMS: Increased salivary pepsin could indicate an increase in gastro-esophageal reflux, however, previous studies failed to demonstrate a correlation between salivary pepsin concentrations and 24-hour esophageal acid exposure. This study... -
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- Impedance pH Monitoring: Intra-observer and Inter-observer Agreement and Usefulness of a Rapid Analysis of Symptom Reflux Association
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Tenca A, Campagnola P, Bravi I, Benini L, Sifrim D, Penagini R
- KMID: 2381172
- J Neurogastroenterol Motil.
- 2014 Apr;20(2):205-211.
BACKGROUND/AIMS: Symptom reflux association analysis is especially helpful for evaluation and management of proton pump inhibitor (PPI) refractory patients. An accurate calculation requires manual editing of 24-hour multichannel intraluminal impedance-pH... -
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- Esophageal Baseline Impedance Reflects Mucosal Integrity and Predicts Symptomatic Outcome With Proton Pump Inhibitor Treatment
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Xie C, Sifrim D, Li Y, Chen M, Xiao Y
- KMID: 2417271
- J Neurogastroenterol Motil.
- 2018 Jan;24(1):43-50.
- doi: 10.5056/jnm17032
BACKGROUND/AIMS: Esophageal baseline impedance, which is decreased in gastroesophageal reflux disease (GERD) patients, is related to the severity of acid reflux and the integrity of the esophageal mucosa. The study... -
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- Inconsistency in the Diagnosis of Functional Heartburn: Usefulness of Prolonged Wireless pH Monitoring in Patients With Proton Pump Inhibitor Refractory Gastroesophageal Reflux Disease
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Penagini R, Sweis R, Mauro A, Domingues , Vales A, Sifrim D
- KMID: 2381258
- J Neurogastroenterol Motil.
- 2015 Apr;21(2):265-272.
- doi: 10.5056/jnm14075
BACKGROUND/AIMS: The diagnosis of functional heartburn is important for management, however it stands on fragile pH monitoring variables, ie, acid exposure time varies from day to day and symptoms are... -
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