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Results of Arthroscopically Assisted Volar and Dorsal Scapholunate Ligament Reconstruction Using Flexor Carpi Radialis: Modified Arthroscopic Corella Technique

Park YC, Kim MS, Lee YK, Seo CY, Shin SG

Purpose: We evaluated results of arthroscopically assisted volar and dorsal scapholunate(SL) ligament reconstruction using flexor carpi radialis(FCR). Methods: We reviewed 31 cases who had been operated from August 2015 to...
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Translational and Clinical Pharmacology: Note from the new Editor-in-Chief

Shin SG

No abstract available.
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Primary Hepatic Schwannoma

Choi YI, Kim YS, Kim JH, Lee SH, Shin SG, Kim YS, Choi DJ, Choi SJ, Chung DH, Kwon OS

A primary benign schwannoma of the liver is extremely rare. Only 30 cases have been reported in the medical literature worldwide, and only one case has been reported in Korea...
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Prediction and visualization of CYP2D6 genotype-based phenotype using clustering algorithms

Kim EY, Shin SG, Shin JG

This study focused on the role of cytochrome P450 2D6 (CYP2D6) genotypes to predict phenotypes in the metabolism of dextromethorphan. CYP2D6 genotypes and metabolic ratios (MRs) of dextromethorphan were determined...
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Role of Coagulation Factor 2 Receptor during Respiratory Pneumococcal Infections

Shin SG, Bong Y, Lim JH

Coagulation factor 2 receptor (F2R), also well-known as a protease-activated receptor 1 (PAR1), is the first known thrombin receptor and plays a critical role in transmitting thrombin-mediated activation of intracellular...
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Fifteen-year Experience with Telemedicine Services in Gangwon Province in Korea

Kim HG, Ahn ME, Choi YA, Choi EH, Kim DW, Shin SG, Park KS, Han JH

OBJECTIVES: This study attempted to identify the factors that contribute to successful telemedicine service. This was done by analyzing the operational state of successful telemedicine services offered in Gangwon Province...
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Interleukin-1beta Participates in the Development of Pneumococcal Acute Lung Injury and Death by Promoting Alveolar Microvascular Leakage

Bong Y, Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae (S. pneumoniae, also known as pneumococcus) infections are major causes of death worldwide. Despite the development and use of effective antibiotics, high, early mortality due to pneumococcal infections...
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Hyperphosphatemia is associated with patency loss of arteriovenous fistula after 1 year of hemodialysis

Moon JY, Lee HM, Lee SH, Lee TW, Ihm CG, Jo YI, Han SW, Shin SG

BACKGROUND: The patency of arteriovenous access is important for stable and effective hemodialysis, and long-term technical survival is best achieved with a native arteriovenous fistula (AVF). However, maintaining AVF patency...
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History of clinical pharmacology in Korea

Shin SG

No abstract available.
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The in vivo and in vitro Roles of Epithelial Pattern Recognition Receptors in Pneumococcal Infections

Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae, also called pneumococcus, is a major cause of infectious disease in human. Pneumococcus resides in the nasopharynx as an upper respiratory commensal, and most of pneumococcal colonizations are...
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Pharmacokinetics of T-614 after Single Oral Administration in Healthy Korean Volunteers

Shin D, Kim BH, Kim JR, Lim KS, Jang IJ, Shin SG, Yu KS

BACKGROUND: Iguratimod is a new type of disease modifying anti-rheumatic drug, which reduced the production of inflammatory cytokines. The purpose of this study was to evaluate pharmacokinetic characteristics and safety...
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A Randomized, Placebo Controlled, Double Blind, Parallel Group, Multiple Dosing, Dose Escalation Clinical Study to Evaluate Pharmacokinetics/Pharmacodynamics and Tolerability of Zofenopril in Healthy Korean Subjects

Oh J, Lee S, Lim KS, Chung JY, Shin SG, Jang IJ, Yu KS

  • KMID: 2334545
  • J Korean Soc Clin Pharmacol Ther.
  • 2013 Jun;21(1):52-62.
BACKGROUND: Zofenopril is a new Angiotensin Converting Enzyme (ACE) inhibitor for the treatment of the patients with hypertension and congestive heart failure. This study aimed to evaluate the pharmacokinetics (PKs)/pharmacodynamics...
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The Short Term Results of All-inside Arthroscopic Repair of the Triangular Fibrocartilage Complex Type 1B Tear by Knotless Suture Anchor

Park YC, Kim MS, Seo CY, Kim JS, Shin SG, Lee JH

PURPOSE: We studied the short term results of the arthroscopic repair of 1B type triangular fibrocartilage complex (TFCC) tear using a knotless suture anchor. METHODS: We evaluated 23 patients who underwent...
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Results of 2012 KoNECT Certification Program of the Human Resource Project

Seong SJ, Lim MS, Oak S, Lee J, Park SM, Park J, Seo JJ, Lee HW, Shin SG, Park MS, Yoon YR

  • KMID: 2334538
  • J Korean Soc Clin Pharmacol Ther.
  • 2012 Dec;20(2):182-194.
BACKGROUND: In recent years, clinical trials have considerably increased and relevant education programs to clinical trials have been developed and implemented since 2008 in Korea. To enhance the quality as...
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Tolerability and Pharmacokinetics Following a Single Dose of Vardenafil in Healthy Korean Volunteers

Kim S, Lee S, Lim KS, Lim HS, Shin SG, Jang IJ, Yu KS

  • KMID: 2334532
  • J Korean Soc Clin Pharmacol Ther.
  • 2012 Dec;20(2):125-134.
BACKGROUND: Vardenafil is a phosphodiesterase type 5 inhibitor, used in erectile dysfunction. This study aimed to evaluate the pharmacokinetics and tolerability of vardenafil following a single oral administration in healthy...
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Pharmacokinetics and Tolerability Evaluation of Human Coagulation Recombinant Factor VIII (GreenGene(TM)) in Hemophilia A Patients

Han H, Shin KH, Paik SH, Chung JY, Lim KS, Cho JY, Yoon SH, Shin SG, Jang IJ, Yu KS

  • KMID: 2334498
  • J Korean Soc Clin Pharmacol Ther.
  • 2011 Dec;19(2):144-151.
BACKGROUND: GreenGene(TM) (Green Cross Corp.) is a recombinant clotting factor VIII which is used for hemophilia A. This study aimed to investigate the pharmacokinetics and safety profiles of 25 IU/kg...
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Pharmacokinetics and Tolerability Evaluation of Fudosteine after Oral Administration in Healthy Korean Volunteers

Ahn LY, Shin KH, Lim KS, Chung JY, Lee SI, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS

  • KMID: 2334493
  • J Korean Soc Clin Pharmacol Ther.
  • 2011 Dec;19(2):91-97.
BACKGROUND: Fudosteine, (-)-(R)-2-amino-3-(3-hydroxypropylthio)propionic acid, is a cysteine derivative that was approved in Japan, as a new mucoactive agent. The aim of this study was to evaluate the tolerability and pharmacokinetics...
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Evaluation of Pharmacokinetics and Tolerability of Eplerenone after Multiple Oral Doses of 100 mg in Healthy Korean Volunteers

Yoon S, Lee S, Oh DS, Lim KS, Shin SG, Jang IJ, Yu KS

  • KMID: 2334492
  • J Korean Soc Clin Pharmacol Ther.
  • 2011 Dec;19(2):84-90.
BACKGROUND: Eplerenone is a selective mineralocorticoid receptor antagonist which effectively blocks mineralocorticoid receptors in various tissues throughout the body. The addition of eplerenone to optimal medical therapy reduces morbidity and...
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Influence of Simvastatin on Pharmacokinetics/Pharmacodynamics of Aspirin after Oral Co-administration in Healthy Volunteers

Gu N, Kim BH, Chung YJ, Lim KS, Seo HB, Yim DS, Shin SG, Jang IJ, Yu KS

  • KMID: 2334491
  • J Korean Soc Clin Pharmacol Ther.
  • 2011 Dec;19(2):73-83.
BACKGROUND: Both aspirin and simvastatin are prescribed as treatments or prevention of cardiovascular diseases. The aim of this study was to investigate the influence of simvastatin on pharmacokinetics and pharmacodynamics...
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Asian society of gynecologic oncology workshop 2010

Suh DH, Kim JW, Aziz MF, Devi UK, Ngan HY, Nam JH, Kim SC, Kato T, Ryu HS, Fujii S, Lee YS, Kim JH, Kim TJ, Kim YT, Wang KL, Lee TS, Ushijima K, Shin SG, Chia YN, Wilailak S, Park SY, Katabuchi , Kamura T, Kang SB

This workshop was held on July 31-August 1, 2010 and was organized to promote the academic environment and to enhance the communication among Asian countries prior to the 2nd biennial...
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