- Dihydroaustrasulfone alcohol induces apoptosis in nasopharyngeal cancer cells by inducing reactive oxygen speciesdependent inactivation of the PI3K/AKT pathway
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Tan KT, Shih YH, Gong JY, Zhang X, Huang CY, Su JH, Sheu JH, Lin CC
- KMID: 2544140
- Korean J Physiol Pharmacol.
- 2023 Jul;27(4):383-398.
- doi: 10.4196/kjpp.2023.27.4.383
Dihydroaustrasulfone alcohol (DA), the synthetic precursor of a natural compound (austrasulfone) isolated from the coral species Cladiella australis, has shown cytotoxic effects against cancer cells. However, it is unknown whether... -
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- Nucleophosmin modulates the alleviation of atopic dermatitis caused by the marine-derived compound dihydroaustrasulfone alcohol
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Hung HC, Feng CW, Lin YY, Chen CH, Tsui KH, Chen WF, Pan CY, Sheu JH, Sung CS, Wen ZH
- KMID: 2440028
- Exp Mol Med.
- 2018 Feb;50(2):e446.
- doi: 10.1038/emm.2017.272
Atopic dermatitis (AD) is a chronic inflammatory skin disease, and its prevalence is increasing. AD usually elicits skin barrier dysfunction, dry skin and itching. As the mechanisms of AD remain... -
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