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Dual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways

McEnerney , Duncan K, Bang BR, Elmasry S, Li M, Miki T, Ramakrishnan SK, Shah YM, Saito T

The hepatic lobule is divided into three zones along the portal-central vein axis. Hepatocytes within each zone exhibit a distinctive gene expression profile that coordinates their metabolic compartmentalization. The zone-dependent...
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