- Pachymic Acid Enhances Pentobarbital-Induced Sleeping Behaviors via GABA(A)-ergic Systems in Mice
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Shah VK, Choi JJ, Han JY, Lee MK, Hong JT, Oh KW
- KMID: 2170625
- Biomol Ther.
- 2014 Jul;22(4):314-320.
This study was investigated to know whether pachymic acid (PA), one of the predominant triterpenoids in Poria cocos (Hoelen) has the sedative-hypnotic effects, and underlying mechanisms are mediated via gamma-aminobutyric... -
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- Poria cocos ethanol extract and its active constituent, pachymic acid, modulate sleep architectures via activation of GABA(A)-ergic transmission in rats
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Shah VK, Na SS, Chong MS, Woo JH, Kwon YO, Lee MK, Oh KW
- KMID: 2169088
- J Biomed Res.
- 2015 Sep;16(3):84-92.
- doi: 10.12729/jbr.2015.16.3.084
Poria cocos is a well-known traditional Chinese traditional medicine (TCM) that grows around roots of pine trees in China, Korea, Japan, and North America. Poria cocos has been used in... -
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