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Endoscopic Features of Mucous Cap Polyps: A Way to Predict Serrated Polyps

Moy BT, Forouhar F, Kuo CL, Devers TJ

BACKGROUND/AIMS: The aims of the study were to identify whether a mucous-cap predicts the presence of serrated polyps, and to determine whether additional endoscopic findings predict the presence of a...
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Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma

Park SJ, Yoon H, Jung IS, Shin CM, Park YS, Kim NY, Lee DH

BACKGROUND/AIMS: Sessile serrated adenomas (SSAs) are known to be precursors of colorectal cancer (CRC). The proper interval of follow-up colonoscopy for SSAs is still being debated. We sought to determine...
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Clinical characteristics of patients with serrated polyposis syndrome in Korea: comparison with Western patients

Kim ER, Jeon J, Lee JH, Lee YJ, Hong SN, Chang DK, Kim YH

BACKGROUND/AIMS: Serrated polyposis syndrome (SPS) has been shown to increase the risk of colorectal cancer (CRC). However, little is known about the characteristics of Asian patients with SPS. This study...
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Comparisons of Gut Microbiota Among Healthy Control, Patients With Conventional Adenoma, Sessile Serrated Adenoma, and Colorectal Cancer

Yoon H, Kim N, Park JH, Kim YS, Lee J, Kim HW, Choi YJ, Shin CM, Park YS, Lee DH, Jung HC

BACKGROUND: Studies on gut microbiota regarding colorectal carcinogenesis, including sessile serrated adenoma (SSA), have been scarce. The aim of this study is to investigate the role of mucosa-associated gut microbiota...
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Sessile Serrated Adenomas: How to Detect, Characterize and Resect

Ma MX, Bourke MJ

Serrated polyps are important contributors to the burden of colorectal cancers (CRC). These lesions were once considered to have no malignant potential, but currently up to 30% of all CRC...
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Serrated Adenoma with Adenocarcinoma of Stomach Treated by Endoscopic Submucosal Dissection

Park BW, Lee TY, Kim MS, Lee JH, Kim KS, Lee JS

Since the first case of gastric serrated adenoma found in 2001, 35 additional cases have been reported. Among these cases, 26 cases were associated with invasive adenocarcinoma within the serrated...
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Characteristics and outcomes of endoscopically resected colorectal cancers that arose from sessile serrated adenomas and traditional serrated adenomas

Seo JY, Choi SH, Chun J, Lee C, Choi JM, Jin EH, Hwang SW, Im JP, Kim SG, Kim JS

BACKGROUND/AIMS: The efficacy and safety of endoscopic resection of colorectal cancer derived from sessile serrated adenomas or traditional serrated adenomas are still unknown. The aims of this study were to...
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Pathogenesis and Management of Serrated Polyps: Current Status and Future Directions

Anderson J

Hyperplastic or serrated polyps were once believed to have little to no clinical significance. A subset of these polyps are now considered to be precursors to colorectal cancers (CRC) in...
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Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and a Literature Review of 13 Cronkhite-Canada Syndrome Cases in Korea

Yun SH, Cho JW, Kim JW, Kim JK, Park MS, Lee NE, Lee JU, Lee YJ

Cronkhite-Canada syndrome (CCS) is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances both in the gastrointestinal tract and in the epidermis. The pathologic finding of the polyp is usually...
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Immunohistochemical Expression of p53, Bcl-2, and Ki-67 Proteins in Traditional Serrated Adenomas of Colon

Jung JH, Kwon HJ, Kim TJ, Cho HJ, Kim HK, Cheung DY, Kim JI, Kim JK

BACKGROUND/AIMS: Serrated adenomas of the colon show mixed characteristics of both hyperplastic and adenomatous polyps. Serrated adenomas are known to progress via the serrated pathway than the adenoma-carcinoma pathway. The...
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Sessile Serrated Adenoma with High-grade Dysplasia

Kwon KJ, Jung SA, Shim KN, Chung JH, Kang SH, Song DK, Jun SJ, Kim HI

Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some...
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Early Adenocarcinoma Arising from Traditional Serrated Adenoma in the Colon

Kim MK, Cha JM, Lim SJ, Kim S, Chae JM, Jo U, Joo KR, Lee JI

  • KMID: 1935719
  • Korean J Gastrointest Endosc.
  • 2011 Feb;42(2):113-117.
A serrated adenoma is a precursor lesion for some cases of microsatellite unstable colorectal carcinoma (CRC). The serrated neoplasia pathway has been associated with carcinogenesis of serrated adenoma, which is...
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A Significant Number of Sessile Serrated Adenomas Might Not Be Accurately Diagnosed in Daily Practice

Kim SW, Cha JM, Lee JI, Joo KR, Shin HP, Kim GY, Lim SJ

  • KMID: 2167256
  • Gut Liver.
  • 2010 Dec;4(4):498-502.
BACKGROUND/AIMS: The diagnosis of hyperplastic polyps (HPs) may involve a conglomeration of subgroups of serrated polyps. The diagnosis of HPs may therefore be revisited if this is sessile serrated adenoma...
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Expression of beta-catenin, hMLH1, p53, Bcl-2, Bax and COX-2 in Serrated Adenomas of Colon

Choi KW, Jang BI, Eun JR, Lee JH, Bae YK, Kim TN

  • KMID: 2304819
  • Korean J Gastrointest Endosc.
  • 2007 Jan;34(1):19-27.
BACKGROUND/AIMS: Serrated adenoma of the colorectum is a recently proposed entity that is characterized by a saw-toothed structure of hyperplastic polyp and also the cytologic atypia of conventional adenoma. In...
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Clinical Features of Colorectal Serrated Adenomas

Kim HJ, Kim TH, Lim BL, Jung GA, Kim HJ, Jung WT, Joo YT, Choi SK, Lee JH

  • KMID: 2199261
  • J Korean Soc Coloproctol.
  • 2006 Apr;22(2):91-96.
PURPOSE: Colorectal cancer is believed to progress through an adenoma-carcinoma sequence. However, recent evidence increasingly supports the existence of an alternative route for colorectal carcinogenesis through a serrated adenoma, which...
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A Case of Serrated Adenoma Presenting as Colon Cancer

Seo IS, Kim YH, Park SM, Cho JW, Lee YU, Ju MJ

  • KMID: 2014294
  • Korean J Gastrointest Endosc.
  • 2005 Feb;30(2):103-107.
Serrated adenoma (SA) is a distinct form of colorectal neoplasia and it is defined as a neoplastic lesion composed of a monotonous cell population with atypical nuclei proliferating in serrated...
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The Histologic and Colonoscopic Features and p53 Protein Overexpression of Serrated Adenoma

Kim SG, Lee MS, Kim JO, Cheon GJ, Jung IS, Cheon YK, Cho JY, Lee JS, Jin SY, Shim CS

  • KMID: 2085017
  • Korean J Gastroenterol.
  • 2002 May;39(5):350-355.
BACKGROUND/AIMS: Serrated adenomas (SA) is a distinct form of colorectal neoplasia, in which adenomatous glands have a serrated epithelial arrangement observed in hyperplastic polyps. SA is defined as a neoplastic...
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