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Effect of Serotonin on Experimentally Induced Gastric Ulcer in Rats

Chang MH, Choi BH, Hong SS

Ulcerative gastric lesions in rats were produced by the procedure of Shay et al. The lesion develops uniformly in the rumen, less often in the antrum, and least frequently in...
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Effect of Serotonin on Gastric Secretion in the Dog

Whang KC, Hong SS, Cho TS, Lee WC

Heidenhain pouch secretion in response to small dose of serotonin was studied in conscious dogs. A single subcutaneous injection of 0.5 to 2.0 mg of serotonin produced no changes in...
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Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase

Sung DJ, Noh HJ, Kim JG, Park SW, Kim B, Cho H, Bae YM

  • KMID: 2154286
  • Exp Mol Med.
  • 2013 Dec;45(12):e67.
Serotonin (5-hydroxytryptamine (5-HT)) is a neurotransmitter that regulates a variety of functions in the nervous, gastrointestinal and cardiovascular systems. Despite such importance, 5-HT signaling pathways are not entirely clear. We...
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Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.

Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA

  • KMID: 1457534
  • Exp Mol Med.
  • 2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the...
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