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Incidence and risk factors associated with early death in patients with emergency department septic shock

Reaven MS, Rozario NL, McCarter MSJ, Heffner AC

Background: Limited research has explored early mortality among patients presenting with septic shock. The objective of this study was to determine the incidence and factors associated with early death following...
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Serum lactate levels in cirrhosis and non-cirrhosis patients with septic shock

Tongyoo S, Sutthipool K, Viarasilpa T, Permpikul C

Background: In septic shock patients with cirrhosis, impaired liver function might decrease lactate elimination and produce a higher lactate level. This study investigated differences in initial lactate, lactate clearance, and...
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Usefulness of presepsin in predicting the prognosis of patients with sepsis or septic shock: a retrospective cohort study

Koh JS, Kim YJ, Kang DH, Lee JE, Lee SI

Background: The diagnosis and prediction of prognosis are important in patients with sepsis, and presepsin is helpful. In this study, we aimed to examine the usefulness of presepsin in predicting...
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Shock Thyroid in a Patient with Septic Shock: A Case Report and Literature Review

Kim WH, Kim MS, Kim JH, Lee KH, Lee JH

Shock thyroid is a rare manifestation of the CT hypotension complex and can be diagnosed when thyroid and perithyroidal edemas are observed on CT during the onset of shock. Shock...
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Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis

Hanumanthu BKJ, Nair AS, Katamreddy A, Gilbert JS, You JY, Offor OL, Kushwaha A, Krishnan A, Napolitano M, Palaidimos L, Morante J, Tekwani SS, Mehta S, Gupta A, Goraya H, Sun M, Faillace RT, Gulani P

Background: Patients with sepsis are at risk for developing sepsis-induced cardiomyopathy (SIC). Previous studies offer inconsistent results regarding the association of SIC and mortality. This study sought to assess whether...
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The Efficacy of vitamin C, thiamine, and corticosteroid therapy in adult sepsis patients: a systematic review and meta-analysis

Somagutta MKR, Pormento MKL, Khan MA, Hamdan A, Hange N, KC M, Pagad S, Jain MS, Lingarajah S, Sharma V, Kaur J, Emuze B, Batti E, Iloeje OJ

Background: Previous studies have suggested favorable outcomes of hydrocortisone, ascorbic acid (vitamin C), and thiamine (HAT) therapy in patients with sepsis. However, similar results have not been duplicated in sequential...
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Circumferential esophageal perforation resulting in tension hydropneumothorax in a patient with septic shock

Saffo S, Farrell J, Nagar A

Esophageal perforations occur traumatically or spontaneously and are typically associated with high mortality rates. Early recognition and prompt management are essential. We present the case of a 76-year-old man who...
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Changes in the epidemiology and management of bacterial infections in cirrhosis

Piano S, Tonon M, Angeli P

Patients with cirrhosis are susceptible to develop infections because of immune dysfunction, changes in microbiome and increase in bacterial translocation from the gut to systemic circulation. Bacterial infections can worse...
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Pulse pressure during the initial resuscitative period in patients with septic shock treated with a protocol-driven resuscitation bundle therapy

Lee SH, Kim YJ, Yu GN, Jeon JC, Kim WY

Background/Aims: Maintaining a mean arterial pressure (MAP) ≥ 65 mmHg during septic shock should be based on individual circumstances, but specific target is poorly understood. We investigated associations between time-weighted...
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A Fatal Case of Bacteremia Caused by Vibrio cholerae Non-O1/O139

Hwang S, Kim Y, Jung H, Chang HH, Kim SJ, Park HK, Lee JM, Kim HI, Kim SW

Vibrio cholerae is a pathogen known to cause the waterborne epidemic disease cholera. Overall, V. cholerae O1 or O139 strains produce the cholera toxin that cause gastroenteritis, resulting in watery...
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Refractory gram-negative septic shock complicated by extended purpura fulminans and multiple organ failure in a 23-year-old puerpera -a case report-

Viderman D, Umbetzhanov Y, Temirov T, Kuzkov VV

Background: Pregnancy-related infections are the third most common cause of maternal death worldwideThe aim of this report is to present a case of pregnancy-related infection, which progressed into refractory...
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Up-to-date information on polymyxin B-immobilized fiber column direct hemoperfusion for septic shock

Mitaka C, Kusaoi M, Kawagoe I, Satoh D

Endotoxin adsorption therapy by polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP) has been used for the treatment of septic shock patients. Endotoxin, an outer membrane component of Gram-negative bacteria, plays...
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Differences between Risk Factors for Sepsis and Septic Shock in Obstructive Urolithiasis

Lee SH, Choi Ts, Choi Jh, Yoo KH

Background: Complicated acute pyelonephritis (APN) is a life-threatening condition that requires immediate intervention. This study examined the characteristics of APN occurring as a complication of ureteral stone. Methods: We retrospectively reviewed...
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The Effect of the Vitamin Protocol for Treating Sepsis or Septic Shock in Pediatric Intensive Care Unit

Ko HJ, Jung MJ, Kim JS, Son ES, Yu YM

Background: Recently, a study comprising adult patients with sepsis admitted in the intensive care unit (ICU) was conducted. The patients were treated with high doses of intravenous ascorbic acid, thiamine,...
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Incidence and clinical course of septic shock in neutropenic patients during chemotherapy for gynecological cancers

Yoo J, Jung Y, Ahn JH, Choi YJ, Lee KH, Hur S

Objective: To identify the incidence and clinical course of septic shock combined with neutropenia during chemotherapy in gynecological cancer patients. Methods: We retrospectively reviewed the medical records of all gynecological cancer...
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Association between body temperature measured at the emergency department with prognosis in septic shock patients

Choi JH, Park YS, Chung SP, Shin TG, Kim WY, Choi SH, Jo YH, Kang GH, Shin J, Lim TH, Han KS, Suh GJ, Korean Shock Society (KoSS) Investigators

  • KMID: 2506061
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):346-354.
Objective: Prior studies have explored the relationship between initial body temperature (BT) and mortality in patients with sepsis in the emergency department (ED). However, there has been no study on...
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Thromboelastographic Evaluation in Patients with Severe Sepsis or Septic Shock: A Preliminary Analysis

Yoon S, Lim J, Park CM, Lee DS, Park JB, Choi K, Yoo K, Gil E, Yoon KW

Purpose: Thromboelastography (TEG) was investigated for the diagnosis of coagulopathy compared with traditional coagulation tests, in association with disease severity in patients with severe sepsis or septic shock. Methods: Retrospective data...
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Cancer patients with neutropenic septic shock: etiology and antimicrobial resistance

Jung SM, Kim YJ, Ryoo SM, Sohn CH, Seo DW, Lim KS, Kim WY

Background/Aims: Among patients with febrile neutropenia that developed after chemotherapy, high-risk patients, such as those having clinical instability or Multinational Association of Supportive Care in Cancer score of < 21,...
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Effect of vasopressin on prognosis in sepsis shock

Kim S, Lee KH, Min MK, Ryu JH, Lee DS, Lee MJ, Wang IJ

  • KMID: 2500263
  • J Korean Soc Emerg Med.
  • 2020 Apr;31(2):146-151.
Objective: This study analyzed the relationship between the timing of vasopressin treatment and the prognosis of patients with septic shock. Methods: Patients who were admitted to a university hospital for one year...
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The Role of Butyrate in Attenuating Pathobiont-Induced Hyperinflammation

Chen J, Vitetta L

An excessive hyperinflammatory response-caused septic shock is a major medical problem that is associated with pathogenic bacterial infections leading to high mortality rates. The intestinal microbiota and the associated elaborated...
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