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Giant juvenile fibroadenoma of the breast: a case report and brief literature review

Song BS, Kim EK, Seol H, Seo JH, Lee JA, Kim DH, Lim JS

A girl (age, 12 years 11 months) consulted the pediatric endocrinology clinic because of a rapidly growing right breast mass over 13 cm observed during the preceding 3 months. A...
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Rhabdoid Colorectal Carcinomas: Reports of Two Cases

Lee SH, Seol H, Kim WY, Lim SD, Kim WS, Hwang TS, Han HS

  • KMID: 2277414
  • Korean J Pathol.
  • 2013 Aug;47(4):372-377.
Rhabdoid colorectal carcinomas are very rare and only 10 cases have been previously reported. We report two cases of rhabdoid colorectal carcinoma, one arising in the sigmoid colon of a...
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Invasive Cribriform Carcinoma Arising in Malignant Phyllodes Tumor of Breast: A Case Report

Choi Y, Lee KY, Jang MH, Seol H, Kim SW, Park SY

  • KMID: 2011991
  • Korean J Pathol.
  • 2012 Apr;46(2):205-209.
Phyllodes tumor is an uncommon fibroepithelial neoplasm of the breast. And it is characterized by expanded stroma with increased cellularity and elongated epithelium-lined clefts. Mammary carcinomas within phyllodes tumors have...
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Histological and Immunohistochemical Evaluation of Ductal Carcinoma In Situ Co-Existing with Triple-Negative Carcinoma of the Breast

Seol H, Ko H, Park IA

  • KMID: 1163180
  • Korean J Pathol.
  • 2008 Dec;42(6):373-380.
BACKGROUND: Triple-negative breast carcinomas (TNBCs) are associated with high-grade histological tumor and a poor clinical outcome. In this study, we evaluated the histology and immunohistochemical features of DCIS co-existing with...
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Cancer Subtypes of Breast Carcinoma with Micropapillary and Mucinous Component Based on Immunohistochemical Profile

Min SY, Jung EJ, Seol H, Park IA

BACKGROUND: Micropapillary carcinoma (MPC) is known to have a worse prognosis than the other subtypes of breast cancer. Occasionally, MPC is observed in association with invasive ductal carcinoma not otherwise...
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Fine Needle Aspiration Cytology of Parathyroid Lesions

Heo I, Park S, Jung CW, Koh JS, Lee SS, Seol H, Choi HS, Cho SY

  • KMID: 2141008
  • Korean J Pathol.
  • 2013 Oct;47(5):466-471.
BACKGROUND: There has been an increase in the use of fine needle aspiration cytology (FNAC) for the diagnosis of parathyroid lesions (PLs). Differentiation between a thyroid lesion and a PL...
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Fine-Needle Aspiration Cytology of Pleomorphic Carcinomas of the Lung

Choi HS, Seol H, Heo IY, Jung CW, Cho SY, Park S, Koh JS, Lee SS

  • KMID: 2012062
  • Korean J Pathol.
  • 2012 Dec;46(6):576-582.
BACKGROUND: Pleomorphic carcinoma (PC) is a rare pulmonary malignancy. Because of its rarity and histological heterogeneity, cytopathologists might suspect PC only rarely on the basis of its cytological specimen. In...
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The Significance of p-AKT1 as a Prognostic Marker and Therapeutic Target in Patients With Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor-2-Positive Early Breast Cancer

Kim JY, Park CS, Jang SK, Seol H, Seong MK, Noh WC, Park IC, Kim HA

Purpose: Phosphorylated AKT1 (p-AKT1) at Ser473 is a functional isoform of AKT and a key component of the PI3K/mTOR/AKT pathway. This study aimed to evaluate the prognostic significance of p-AKT1...
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Phosphorylated S6 Kinase-1 as Predictive Marker of Lapatinib Efficacy in Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer Patients

Ko EB, Seong MK, Choi HS, Park CS, Choi JH, Lee JK, Seol H, Kim HA, Noh WC

PURPOSE: The 40S ribosomal protein S6 kinase-1 (S6K1) is a crucial downstream effector of the PI3K/AKT/mTOR pathway. S6K1 overexpression is found in 10% to 30% of breast cancers and is...
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Expression of Immunohistochemical Markers before and after Neoadjuvant Chemotherapy in Breast Carcinoma, and Their Use as Predictors of Response

Lee HC, Ko H, Seol H, Noh DY, Han W, Kim TY, Im SA, Park IA

PURPOSE: For patients with breast carcinoma, immunohistochemical markers are important factors in determining the breast cancer subtype and for establishing a therapeutic plan, including the use of neoadjuvant chemotherapy (NACT)....
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Serial Serum HER2 Measurements for the Detection of Breast Cancer Recurrence in HER2-Positive Patients

Ha JH, Seong MK, Kim EK, Lee JK, Seol H, Lee JY, Byeon J, Sohn YJ, Koh JS, Park IC, Noh WC, Kim HA

  • KMID: 2353081
  • J Breast Cancer.
  • 2014 Mar;17(1):33-39.
PURPOSE: The measurement of serum human epidermal growth factor receptor 2 (HER2) extracellular domain levels is a well-established method for evaluating whether a metastatic HER2-positive breast cancer patient will respond...
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Predicting the Benefit of Adjuvant Aromatase Inhibitor Therapy in Postmenopausal Breast Cancer Patients with Phosphorylated S6K1 Expression Status

Choi J, Park CS, Seong MK, Seol H, Kim JS, Park IC, Noh WC, Kim HA

PURPOSE: Phosphorylated ribosomal S6 kinase 1 (pS6K1) is a major downstream regulator of the mammalian target of rapamycin (mTOR) pathway. Recent studies have addressed the role of S6K1 in adipogenesis....
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