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Application of DNA chip techniques for Yq microdeletion analysis in infertile males

Lee S, Joo HS, Lee SH, Park JE, Kim JM, Hwang JH, Cho KS, Hwang SY

  • KMID: 1380213
  • Exp Mol Med.
  • 2004 Apr;36(2):179-184.
Our aim was to apply DNA chip technology as a diagnostic tool in infertility research and clinics. Six loci, including a sex-determining region on the Y chromosome and five sequence-tagged...
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Evaluation of a Multiplex PCR Kit Used for Detecting Y Chromosome Microdeletions

Park MY, Kang HM, Hwang SH, Park HJ, Park NC, Choi KU, Kim HH, Chang CL, Lee EY

BACKGROUND: In addition to Klinefelter's syndrome, microdeletion of Yq is the most common genetic cause of male infertility; 15% of azoospermic or 5-10% of oligozoospermic males have Yq deletions. We...
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