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Time-Course Changes in Bone Metabolism Markers and Density in Patients with Osteoporosis Treated with Romosozumab: A Multicenter Retrospective Study

Inage K, Orita S, Eguchi Y, Shiga Y, Koda M, Aoki Y, Kotani T, Akazawa T, Furuya T, Nakamura J, Takahashi H, Suzuki-Narita M, Maki S, Hagiwara S, Inoue M, Norimoto M, Kinoshita H, Sato T, Sato M, Enomoto K, Takaoka H, Mizuki N, Hozumi T, Tsuchiya R, Kim G, Otagiri T, Mukaihata T, Hishiya T, Ohtori S

Purpose: In this multicenter retrospective observational study, we examined the early effects of romosozumab in patients with severe osteoporosis in terms of time-course changes in bone metabolism marker, improvement in...
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Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center Experience

Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K

Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of...
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A Meta-Analysis of Slow Pull versus Suction for Endoscopic Ultrasound-Guided Tissue Acquisition

Nakai Y, Hamada T, Hakuta R, Sato T, Ishigaki K, Saito K, Saito T, Takahara N, Mizuno S, Kogure H, Koike K

Background/Aims: Endoscopic ultrasound (EUS)-guided tissue acquisition is widely utilized as a diagnostic modality for intra-abdominal masses, but there remains debate regarding which suction technique, slow pull (SP) or conventional suction...
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Diffusion Tensor Imaging of the Spinal Canal in Quantitative Assessment of Patients with Lumbar Spinal Canal Stenosis

Norimoto M, Eguchi Y, Kanamoto H, Oikawa Y, Matsumoto K, Masuda Y, Furuya T, Orita S, Inage K, Maki S, Shiga Y, Kinoshita H, Abe K, Inoue M, Umimura T, Sato T, Sato M, Suzuki M, Enomoto K, Ohtori S

Study Design Retrospective observational study. Purpose Lumbar spinal stenosis (LSS) has traditionally been evaluated morphologically, there is a paucity of literature on quantitative assessment of LSS. The purpose of this study was to...
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Two Cases of Severe Type 2 Respiratory Failure Associated with Diffuse Idiopathic Skeletal Hyperostosis

Sato T, Bannai T, Miyake T, Murakami K, Maekawa R, Shiio Y

Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory process characterized by hyperostosis at tendon insertions and around joint capsules and ossification of the anterior longitudinal ligament of the spine. The...
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Relationships between the upper central incisor crown forms and degree of labial inclination, overbite, and overjet in Japanese young adults

Kurita T, Mizuhashi F, Sato T, Koide K

PURPOSE The present study aimed to investigate the relationships between the crown form of the upper central incisor and their labial inclination, overbite, and overjet. MATERIALS AND METHODS Maxillary and...
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Endoscopic Ultrasound-Guided Tissue Acquisition by 22-Gauge Franseen and Standard Needles for Solid Pancreatic Lesions

Ishigaki K, Nakai Y, Oyama H, Kanai S, Suzuki T, Nakamura T, Sato T, Hakuta R, Saito K, Saito T, Takahara N, Hamada T, Mizuno S, Kogure H, Tada M, Isayama H, Koike K

Background/Aims: Recently, a three-plane symmetric nee- dle with Franseen geometry was developed for endoscopic ultrasound-guided fine needle biopsy (EUS-FNB). In this ret-rospective study, tissue acquisition per pass was compared between 22-gauge...
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Long-term outcome after surgery in a patient with intestinal Behçet’s disease complicated by myelodysplastic syndrome and trisomy 8

Mori Y, Iwamoto F, Ishida Y, Kuno T, Kobayashi S, Yoshida T, Yamaguchi T, Sato T, Sudo M, Ichikawa D, Enomoto N

Behçet’s disease (BD) is a multisystem inflammatory disease of unknown origin. Rarely, BD occurs together with myelodysplastic syndrome (MDS). Interestingly, it is speculated that these are not simple coexistence but...
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Management of Difficult Bile Duct Stones by Large Balloon, Cholangioscopy, Enteroscopy and Endosonography

Nakai Y, Sato T, Hakuta R, Ishigaki K, Saito K, Saito T, Takahara N, Hamada T, Mizuno S, Kogure H, Tada M, Isayama H, Koike K

Endoscopic management of bile duct stones is now the standard of care, but challenges remain with difficult bile duct stones. There are some known factors associated with technically difficult bile...
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Short-Term Results of Hybrid Closed-Wedge High Tibial Osteotomy: A Case Series with a Minimum 3-Year Follow-up

Saito H, Saito K, Shimada Y, Yamamura T, Yamada S, Sato T, Nozaka K, Kijima H, Miyakoshi

PURPOSE: High tibial valgus osteotomy (HTO) is a well-established surgical procedure for patients with medial compartment osteoarthritis (OA) of the knee. The hybrid closed-wedge HTO (CWHTO) procedure permits extensive correction...
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Cervical Open-Door Laminoplasty by Hydroxyapatite Implant Insertion Without Suturing

Kawanabe Y, Fujimoto M, Sato T

OBJECTIVE: To assess the efficacy of cervical open-door laminoplasty by hydroxyapatite implant insertion between the lamina and the lateral mass without suturing. METHODS: All patients who underwent cervical open-door laminoplasty with...
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Development and Validation of Generalized Linear Regression Models to Predict Vessel Enhancement on Coronary CT Angiography

Masuda T, Nakaura T, Funama Y, Sato T, Higaki T, Kiguchi M, Matsumoto , Yamashita , Imada N, Awai K

OBJECTIVE: We evaluated the effect of various patient characteristics and time-density curve (TDC)-factors on the test bolus-affected vessel enhancement on coronary computed tomography angiography (CCTA). We also assessed the value...
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Evaluation of the drug-induced lymphocyte stimulation test for diagnosing mesalazine allergy

Saito D, Hayashida , Sato T, Minowa S, Ikezaki O, Mitsui T, Miura M, Sakuraba A, Hisamatsu

BACKGROUND/AIMS: Mesalazine is an effective drug for treating ulcerative colitis (UC), but causes allergic symptoms in a few cases. Therefore, the objective of this study was to evaluate the usefulness...
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Effect of Patient Characteristics on Vessel Enhancement at Lower Extremity CT Angiography

Masuda T, Nakaura T, Funama Y, Sato T, Higaki T, Kiguchi M, Yamashita , Imada N, Awai K

OBJECTIVE: To evaluate the effect of patient characteristics on popliteal aortic contrast enhancement at lower extremity CT angiography (LE-CTA) scanning. MATERIALS AND METHODS: Prior informed consent to participate was obtained from...
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Calcar Femorale in Patients with Osteoarthritis of the Hip Secondary to Developmental Dysplasia

Tetsunaga , Fujiwara K, Endo H, Tetsunaga , Shiota N, Sato T, Ozaki T

BACKGROUND: We investigated whether the calcar femorale, a cortical septum in the region of the lesser trochanter of the femur, correlates with results of femoral stem implantation in patients with...
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Comparison of Glucose Area Under the Curve Measured Using Minimally Invasive Interstitial Fluid Extraction Technology with Continuous Glucose Monitoring System in Diabetic Patients

Uemura M, Yano Y, Suzuki T, Yasuma T, Sato T, Morimoto A, Hosoya S, Suminaka C, Nakajima H, Gabazza EC, Takei Y

BACKGROUND: Continuous glucose monitoring (CGM) is reported to be a useful technique, but difficult or inconvenient for some patients and institutions. We are developing a glucose area under the curve...
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NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases

Sato T, Takagawa T, Kakuta Y, Nishio A, Kawai M, Kamikozuru K, Yokoyama Y, Kita Y, Miyazaki T, Iimuro M, Hida N, Hori K, Ikeuchi H, Nakamura S

BACKGROUND/AIMS: Recent genome-wide analyses have provided strong evidence concerning adverse events caused by thiopurine drugs such as azathioprine (AZA) and 6-mercaptopurine. The strong associations identified between NUDT15 p.Arg139Cys and thiopurine-induced...
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Feasibility of Endoscopic Papillary Large Balloon Dilation in Patients with Difficult Bile Duct Stones without Dilatation of the Lower Part of the Extrahepatic Bile Duct

Fujita Y, Iwasaki A, Sato T, Fujisawa T, Sekino Y, Hosono K, Matsuhashi N, Sakamaki K, Nakajima A, Kubota K

BACKGROUND/AIMS: There is no consensus for using endoscopic papillary large balloon dilation (EPLBD) in patients without dilatation of the lower part of the bile duct (DLBD). We evaluated the feasibility...
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Development of a new reagent for endoscopic ultrasound-guided celiac plexus neurolysis and tumor ablation therapy

Hara K, Yamao K, Mizuno N, Hijioka S, Imaoka H, Tajika M, Tanaka T, Ishihara M, Sato T, Okuno N, Hieda N, Yoshida T, Yasumasa N

BACKGROUND: Both endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) and tumor ablation using ethanol are very common procedures, and the utility of these therapies has already been reported in prominent journals....
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Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring

Ugi S, Maegawa H, Morino K, Nishio Y, Sato T, Okada S, Kikkawa Y, Watanabe T, Nakajima H, Kashiwagi

BACKGROUND: Management of postprandial hyperglycemia is a key aspect in diabetes treatment. We developed a novel system to measure glucose area under the curve (AUC) using minimally invasive interstitial fluid...
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