- Identification of Dammarane-type Triterpenoid Saponins from the Root of Panax ginseng
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Lee DG, Lee J, Yang S, Kim KT, Lee S
- KMID: 2312882
- Nat Prod Sci.
- 2015 Jun;21(2):111-121.
- doi: 10.0000/nps.2015.21.2.111
The root of Panax ginseng, is a Korea traditional medicine, which is used in both raw and processed forms due to their different pharmacological activities. As part of a continued... -
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- Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana
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Li W, Yan XT, Sun YN, Ngan TT, Shim SH, Kim YH
- KMID: 2170628
- Biomol Ther.
- 2014 Jul;22(4):334-340.
In this study, 23 oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. The NF-kappaB inhibitory activity of the isolated compounds was measured in... -
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- The Effects of Ginseng Saponin on Relaxation of Smooth Muscle in the Lower Urinary Tract and the Corpus Cavernosum
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Jung HC, Oh TH
- KMID: 2320165
- Yeungnam Univ J Med.
- 2006 Jun;23(1):52-61.
BACKGROUND: Korean ginseng (KG) has been used as a general tonic, and for voiding dysfunction for a long time in oriental society. However, scientific basic studies on the use of... -
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- Inhibition of MMP-13 mRNA expression by ginseng saponin in fetal rat calvarial cells
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Kim YY, Ciu DZ, Kim YJ
- KMID: 1999757
- J Korean Acad Periodontol.
- 2005 Jun;35(2):277-288.
- doi: 10.5051/jkape.2005.35.2.277
There is a potential role of collagenase-3 in alveolar bone loss and periodontal disease progression, we need to develope or find chemotherapeutic drugs or herbal agents which may regulate the... -
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- Effect of Ginseng Saponins on Nicotine-Induced Dopamine Release in the Rat Nucleus Accumbens and Striatum
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Kim SE, Shim I, Chung JK, Lee MC
- KMID: 1613906
- Korean J Nucl Med.
- 2002 Oct;36(5):277-287.
No abstract available. -
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- Effect of Saponin, Allopurinol and Nimodipine on Noise Induced Treshold Changes of ABRs in Guinea Pigs
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Park YH, Min IK, Nam BH, Park CI
- KMID: 2275945
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Aug;45(8):760-764.
BACKGROUND AND OBJECTIVES: Several studies have demonstrated that noise exposure may result in cochlear damage. The purpose of this study was to evaluate the effect of red Korean ginseng saponin... -
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- The Harmful Effects of Superoxide Radical and the Protective Effect of Ginseng Saponin on Rat Whole Bladder Contractility
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Kim HJ, Park JH, Lee GH, Joo KJ
- KMID: 2292469
- Korean J Urol.
- 2002 Jun;43(6):496-501.
PURPOSE: We investigated the effects of the superoxide radical on rat whole bladder contractility with duroquinone (superoxide radical generator, Dq) and diethyldithiocarbamate (superoxide dismutase inhibitor, DETCA), and the effects of... -
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- Effects of Ginseng Saponin on the Stress-Induced Plasma Corticosterone Levels in Mice
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Kim DH, Min SK, Son BK, Lee SK, Song DK
- KMID: 2340669
- J Korean Neuropsychiatr Assoc.
- 2002 May;41(3):389-398.
OBJECTIVES: The present study was designed to investigate the effect of ginseng saponin and its major active metabolite on the HPA axis under acute stress-i.c.v. injection stress, and immobilization stress,... -
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- Effect of Total Saponin in Proximal Urethra of the Rabbit
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Jung HC, Yu JW, Park JM
- KMID: 1736672
- J Korean Continence Soc.
- 2000 Dec;4(2):33-39.
- doi: 10.5213/jkcs.2000.4.2.33
No abstract available in English. -
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- Effect of Saponin Fraction on Penile Erection of Rat
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Lim CS, Kang YS, Suh JK
- KMID: 1583953
- Korean J Urol.
- 2000 Dec;41(12):1445-1450.
No abstract available. -
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- Effect of Korean Red Ginseng Saponin on Cochlear Damage Induced by Noise Exposure
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Sin GC, Lee SH, Nam BH, Park CI, Nam KY
- KMID: 2274739
- Korean J Otolaryngol-Head Neck Surg.
- 2000 Aug;43(8):804-807.
BACKGROUND AND OBJECTIVES: Exposure to noise results in pertubations of cochlear microcirculation. There is evidence that these events are mediated, in part, by the calcium channel. The subsequent decrease in... -
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- Antioxidative Effect of Ginseng Saponin on Cardiac Endothelial Cells in Culture
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Shin HJ, Kwon YM, Jung TE, Lee DH, Lee JC, Han SS, Kim HT, Park JH, Sung EG, Lee YC
- KMID: 2092717
- Korean J Anat.
- 2000 Feb;33(1):77-88.
The cytotoxic effects of oxygen free radicals and the antioxidative effect of ginseng saponin (SPN) on cardiac endothelial cell cultures derived from 3-day old rats were studied. Reactive oxygen species... -
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- Effect of Panax Ginseng Saponin on Salicylate Ototoxicity in Guinea Pigs
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Chang JW, Sin GC, Lee OY, Nam BH, Park CI
- KMID: 1977692
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Dec;42(12):1497-1500.
BACKGROUND AND OBJECTIVES: Large doses or long-term use of salicylate may cause reversible tinnitus and hearing loss. The exact cause of salicylate ototoxicity in unknown. Decreased cochlear blood flow following... -
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- Influence of Total Ginseng Saponin on Contractile Responses of Vasoconstrictors in the Isolated Rat Aorta
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Chung CH, Hong SP, Cho SH, Hong JG, Lee YK, Lim GH, Yang WH, You HJ, Woo SC, Choi CH, Lim DY
- KMID: 2228845
- Korean Circ J.
- 1999 Sep;29(9):976-984.
- doi: 10.4070/kcj.1999.29.9.976
BACKGROUND: It has been known that Ginseng extract causes the hypotensive action while it rather produces the hypertensive action. Some studies have suggested that Ginseng extract causes a biphasic response... -
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- Effect of Ginseng Saponin on Human Chondrocyte
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Sung JH, Ryu JD, Jung HG, Kim JY
- KMID: 2105496
- J Korean Orthop Assoc.
- 1998 Dec;33(7):1921-1927.
Earlier work suggested that Ginseng saponin had an effect on osteoblast and other cells, but there has been no report on saponin effects on chondrocyte. The purpose of this study... -
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- Effect of Ginseng Saponin on Cultured Osteoblast
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Sung JH, Ryu JD, Kim SS, Kim HW, Han CW, Ko LH, Kim HM, Kim JY
- KMID: 2336072
- J Korean Orthop Assoc.
- 1998 Jun;33(3):868-876.
Earlier work suggested that Ginseng saponin had an effect on healing of fracture and osteoporosis, hut there has heen no report on saponin effects on cultured osteoblast. The purpose of... -
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- The Effects of Ginseng Saponin on Rabbit Cavernosal Smooth Muscle Relaxation in vitro
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Kim HJ, Lee GH, Kim JJ
- KMID: 1884662
- Korean J Urol.
- 1998 May;39(5):443-449.
PURPOSE: Ginseng saponin, the active ingredients extracted from Panax ginseng, has been used as aphrodisiacs in oriental country, however the exact action mechanism of ginseng saponin still remains uncertain.... -
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- Inhibitory effects of ginseng saponins on c-fos mRNA expression and the proliferation of rat aortic vascular smooth muscle cells stimulated by angiotensin II
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Choi W, Jung JY, Kim HS, Yun YP, Park JD, Ahn HY
- KMID: 1562322
- Korean J Physiol Pharmacol.
- 1998 Apr;2(2):201-207.
To evaluate the possibility that the ginseng saponins could be developed as an anti-arteriosclerotic agent, we examined the inhibitory effects of ginseng saponins (total saponin(TS), panaxatriol(PT), panaxadiol(PD)) on the expression of c-fos mRNA... -
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- The Effect of Ginseng Saponin on the Dopaminergic Neurons in the Parkinson's Disease Model in Mice
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Kim CO, Kim KS, Huh YB, Ahn BW, Han BS, Choi KS, Nam KY, Juhng SW
- KMID: 1849798
- Korean J Pathol.
- 1997 Sep;31(9):805-814.
Saponin has been known to be a major antioxidant component in panax ginseng. Recent experimental study suggests that some antioxidant materials prevent Parkinson's disease caused by 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) in... -
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- Effect of Total Saponin on Penile Erection: A Combined in Vitro and in Vivo Study
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Jung HC, Suh JK
- KMID: 1914390
- Korean J Urol.
- 1997 Aug;38(8):866-872.
Korean ginseng (KG) has been used as a general tonic in oriental society The present study was undertaken to elucidate the pharmacologic action and therapeutic effect of KG in penile... -
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