- The Safety and Efficacy of Anakinra, an Interleukin-1 Antagonist in Severe Cases of COVID-19: A Systematic Review and Meta-Analysis
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Somagutta MKR, Pormento MKL, Hamid P, Hamdan A, Khan MA, Desir R, Vijayan R, Shirke S, Jeyakumar R, Dogar Z, Makkar SS, Guntipalli P, Ngardig NN, Nagineni MS, Paul T, Luvsannyam E, Riddick C, Sanchez-Gonzalez MA
- KMID: 2517430
- Infect Chemother.
- 2021 Jun;53(2):221-237.
- doi: 10.3947/ic.2021.0016
This study aims to assess anakinra's safety and efficacy for treating severe coronavirus disease 2019 (COVID-19). Numerous electronic databases were searched and finally 15 studies with a total of 3,530... -
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- A Pathophysiological Perspective on COVID-19's Lethal Complication: From Viremia to Hypersensitivity Pneumonitis-like Immune Dysregulation
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Sanchez-Gonzalez MA, Moskowitz D, Issuree PD, Yatzkan G, Rizvi SA, Day K
- KMID: 2507527
- Infect Chemother.
- 2020 Sep;52(3):335-344.
- doi: 10.3947/ic.2020.52.3.335
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the coronavirus responsible for our recent coronavirus disease 2019 pandemic, is driving a lung immunopathology that strongly resembles a severe form of hypersensitivity... -
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- Effectiveness of Mavrilimumab in Viral Infections Including SARS-CoV-2 Infection - A Brief Review
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Bhatt K, Garimella R, Taugir R, Mehta I, Jamal M, Vijayan R, Offor R, Nwankwo K, Arif U, Waheed K, Kumari P, Lathiya M, Michel G, Pandya N, Halpern J, Nasir H, Sanchez-Gonzalez MA
- KMID: 2514848
- Infect Chemother.
- 2021 Mar;53(1):1-12.
- doi: 10.3947/ic.2020.0109
Hyperinflammation and cytokine storm has been noted as a poor prognostic factor in patients with severe pneumonia related to coronavirus disease 2019 (COVID-19). In COVID-19, pathogenic myeloid cell overactivation is... -
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