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Adjuvant Role of Botulinum Toxin A in the Management of Wounds Accompanied by Parotid Gland or Duct Injuries

Jeong Y, Lee SY, Sung KY

Background: Parotid gland or duct injuries may occur after facial trauma or surgical procedures around the parotid gland. Such injuries often cause saliva to leak into the wound, and as...
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Application of Developmental Principles for Functional Regeneration of Salivary Glands

Lee ES, Adhikari N, Jung JK, An CH, Kim JY, Kim JY

Currently, there has been rapid increase in the studies about salivary production because of the hyposalivation, xerostomia, caused by radiotherapy for head and neck cancer, Sjogren syndrome and aging. An...
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Primary Necrobiotic Xanthogranulomatous Sialadenitis with Submandibular Gland Localization without Skin Involvement

Kang M, Kim NR, Chung DH, Seok JY, Kim DY

Necrobiotic xanthogranulomatous reaction is a multiorgan, non-Langerhans cell histiocytosis with an unknown etiology. Occurrence in the salivary gland is extremely rare. We recently identified a case of necrobiotic xanthogranulomatous sialadenitis...
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Branchial cleft cyst in the parotid gland in a human immunodeficiency virus-negative patient

Park YY, Yoon JS, Bang SS, Ahn HC

In branchial lymphoepithelial cyst (BLEC), which is also known as branchial cleft cyst, the remnants of a branchial arch develop into a cyst, causing swelling. The first case of BLEC...
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Evaluation of Salivary Gland Function Using Diffusion-Weighted Magnetic Resonance Imaging for Follow-Up of Radiation-Induced Xerostomia

Zhang Y, Ou D, Gu Y, He X, Peng W

OBJECTIVE: To investigate the value of diffusion-weighted magnetic resonance imaging (DW-MRI) as a noninvasive tool to assess salivary gland function for follow-up of patients with radiation-induced xerostomia. MATERIALS AND METHODS: This...
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Fine-Needle Aspiration Cytology of Carcinosarcoma in the Salivary Gland: An Extremely Rare Case Report

An HJ, Baek HJ, Kim JP, Kim MH, Song DH

Carcinosarcoma of the salivary gland is an extremely rare tumor that is composed of both malignant epithelial and mesenchymal components. Diagnosing carcinosarcoma with fine-needle aspiration cytology is challenging because of...
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Injection of Botulinum Toxin for Preventing Salivary Gland Toxicity after PSMA Radioligand Therapy: an Empirical Proof of a Promising Concept

Baum RP, Langbein T, Singh A, Shahinfar , Schuchardt C, Volk GF, Kulkarni H

The dose-limiting salivary gland toxicity of ²²⁵Ac-labelled PSMA for treatment of metastatic, castration-resistant prostate cancer remains unresolved. Suppressing the metabolism of the gland by intraparenchymal injections of botulinum toxin appears...
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High Prevalence of Thyroid Disease and Role of Salivary Gland Scintigraphy in Patients with Xerostomia

Jung JH, Lee CH, Son SH, Jeong JH, Jeong SY, Lee SW, Lee J, Ahn BC

PURPOSE: Although Sjögren's syndrome (SS) is the most common disease causing xerostomia, autoimmune thyroid diseases can also affect the salivary glands. The aim of our study was to estimate the...
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Calcium Signaling in Salivary Secretion

Kim JM, Lee SW, Park K

Calcium has versatile roles in diverse physiological functions. Among these functions, intracellular Ca²⁺ plays a key role during the secretion of salivary glands. In this review, we introduce the diverse...
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New Classification Criteria for Primary Sjögren's Syndrome and Salivary Gland Ultrasonography

Lee KA, Kim HR, Lee SH

Primary Sjögren's syndrome (pSS) is a chronic autoimmune inflammatory disorder characterized by lymphocytic infiltration of exocrine organs. Since 1965, several sets of classification criteria for pSS have been proposed by...
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Parotid mandibular bone defect: A case report emphasizing imaging features in plain radiographs and magnetic resonance imaging

Hisatomi M, Munhoz L, Asaumi J, Arita ES

Mandibular bone depression, also known as Stafne bone cavity, is defined as a bone depression filled mainly with salivary gland tissue. Parotid gland bone defects are infrequently observed. We report...
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Malignant Solitary Fibrous Tumor of the Parotid Gland

Kim DH, Cho KJ, Kim JP, Woo SH

Solitary Fibrous tumor is usually arising in the pleura of the thoracic cavity and it has been described in a variety of extrapleural sites including the abdominal cavity, soft tissue,...
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Developmental salivary gland depression in the ascending mandibular ramus: A cone-beam computed tomography study

Chen CA, Ahn Y, Odell S, Mupparapu , Graham DM

A static, unilateral, and focal bone depression located lingually within the ascending ramus, identical to the Stafne's bone cavity of the angle of the mandible, is being reported. During development...
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Radioprotective Effect of Epigallocatechin-3-Gallate on Salivary Gland Dysfunction After Radioiodine Ablation in a Murine Model

Choi JS, An HY, Park IS, Kim SK, Kim YM, Lim JY

OBJECTIVES: Radioiodine (RI) therapy is known to subject cellular components of salivary glands (SG) to oxidative stress leading to SG dysfunction. However, the protective effects of antioxidants on RI-induced SG...
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Plunging Ranulas Revisited: A CT Study with Emphasis on a Defect of the Mylohyoid Muscle as the Primary Route of Lesion Propagation

Lee JY, Lee HY, Kim HJ, Jeong HS, Kim YK, Cha J, Kim ST

OBJECTIVE: The purpose of this study was to clarify the pathogenesis of plunging ranulas in regard of the pathway of lesion propagation using CT scans. MATERIALS AND METHODS: We retrospectively reviewed...
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Assessment of Age-Related Dimensions of the Salivary and Thyroid Glands Using Three-Dimensional Computed Tomography in Children

Hwang SH, Park IJ, Jeong YM, Lee YJ, Kang JM, Seo JH, Joo YH

BACKGROUND AND OBJECTIVES: This study aimed to determine the dimensions of normal salivary and thyroid glands and assess their relationship with respect to age and sex using three-dimensional imaging in...
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The Significance of Ectopic Germinal Centers in the Minor Salivary Gland of Patients with Sjogren's Syndrome

Lee KE, Kang JH, Yim YR, Kim JE, Lee JW, Wen L, Park DJ, Kim TJ, Park YW, Yoon KC, Lee JS, Lee SS

We investigated the clinical and biological significance of germinal centers (GC) present in the minor salivary glands of patients with Sjogren's syndrome (SS). Minor salivary gland tissue biopsies from 93...
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Reconstruction of partial maxillectomy defect with a buccal fat pad flap and application of 4-hexylresorcinol: a case report

Seok H, Kim MK, Kim SG

Mucoepidermoid carcinoma (MEC) is the most common type of malignant neoplasm in the minor salivary gland. The hard palate is a frequently involved site of MEC. The treatment of low-grade...
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Stafne bone cavity and cone-beam computed tomography: a report of two cases

Venkatesh

In 1942 Stafne reported 35 asymptomatic, radiolucent cavities that were unilaterally located in the posterior region of the mandible between the mandibular angle and the third molar, and below the...
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A Convenient and Less Invasive Technique of Labial Minor Salivary Gland Biopsy Using a Minimal Incision With a Needle Tip

Lee WY, Choi YS, Ahn SH, Hah JH

OBJECTIVES: This study was to show the technique and to compare the usefulness and complications of biopsy using a minimal incision with a needle tip of the labial minor salivary...
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