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Efficacy and Safety of 5-Aminolevulinic Acid for Patients with Symptoms of Late-Onset Hypogonadism: A Preliminary Study

Koyasu H, Horie S, Matsushita K, Ashizawa T, Muto S, Isotani S, Tanaka T, Nakajima M, Tsujimura A

Purpose: As the concept of late-onset hypogonadism (LOH) has gained increased attention, the treatment of eugonadal patients with LOH symptom has become a clinical problem. Previous studies have shown the...
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Anti-adhesive effect and safety of a thermosensitive adhesion barrier (Mediclore) for thyroid surgery: a double-blinded randomized controlled trial

Ahn Jh, Yoon SG, Yi JW, Kim Sj, Lee KE

Purpose: Postoperative adhesions after thyroidectomy adversely affect patients’ quality of life. This study assessed the anti-adhesive effect and safety of thermosensitive sol-gel agents for patients undergoing thyroidectomy. Methods: A double-blind parallel-group...
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Factors Influencing Clinical Nurses’ Medication Safety Competence

Kim GH, Lee HJ

Purpose: The purpose of this study was to measure the influence of job stress, critical thinking disposition, and clinical decision-making ability on clinical nurses’ medication safety competence. Methods: A descriptive...
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Crossover Food Businesses in Louisiana, United States: A Descriptive Study of Their Characteristics and Food Safety Training Needs From Public Health Inspectors’ Perspective

Xu W, Watts E, Bombet C, Cater M

Objectives: Integrating retail and manufacturing enables limitless potential for food businesses, but also creates challenges for navigating within complex food safety regulations. From public health inspectors’ (PHIs) perspective, this study...
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Sodium Picosulphate with Magnesium Citrate versus Polyethylene Glycol for Bowel Preparation in Children: A Systematic Review

Dziechciarz P, Ruszczyński M, Horvath A

Purpose: To compare the effectiveness, tolerability, acceptability, and safety of sodium picosulphate with magnesium citrate (PS/Mg) and polyethylene glycol (PEG) in children (≤18 years) preparing for colonoscopy. Methods: Three electronic databases...
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Safety and feasibility of synchronous unilateral nephrectomy and contralateral heminephrectomy for extremely severe autosomal dominant polycystic kidney disease: Techniques and outcome

Han JH, Jeong Sh, Yuk HD, Ku JH, Kwak C, Kim HH, Ahn C, Jeong CW

Purpose: To demonstrate the safety and feasibility of synchronous unilateral nephrectomy and contralateral heminephrectomy in extremely severe autosomal dominant polycystic kidney disease (ADPKD), which corresponds to the Mayo imaging classification...
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Prospects of Hospital Information Systems and Patient Safety in Japan

Nagoshi K, Watari T, Matsumura Y

Objectives: Approximately 20 years have passed since hospital information systems (HISs) featuring full-scale electronic medical records were first implemented in Japan. Patient safety is one of the most important of...
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Missed nursing care and its influencing factors among neonatal intensive care unit nurses in South Korea: a descriptive study

Kim S, Chae SM

Purpose: Preventing missed care is important in neonatal intensive care units (NICUs) due to neonates’ vulnerabilities. This study examined missed care and its influencing factors among NICU nurses. Methods: Missed care...
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Incidence of Unplanned Extubation and Related Factors of Reintubation in the Neonatal Intensive Care Unit

Lim HM, Lee H, Park MJ, Shin JE

Purpose: This descriptive study aimed to identify the incidence and related factors of reintubation after unplanned extubation in the neonatal intensive care unit. Methods: A secondary data analysis was conducted using...
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Understanding Physicians’ and Nurses’ Adaption of National-Leading Patient Safety Culture Policy: A Qualitative Study in Tertiary and General Hospitals in Korea

Lee W, Choi M, Park E, Park E, Kang S, Lee J, Jang SG, Han HR, Lee Si, Choi JE

Background: In Korea, the safety culture is led by national policy. How the policy ensures a patient safety culture needs to be investigated. This study aimed to examine the way...
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Radiation safety for pain physicians: principles and recommendations

Park S, Kim M, Kim JH

C-arm fluoroscopy is a useful tool for interventional pain management. However, with the increasing use of C-arm fluoroscopy, the risk of accumulated radiation exposure is a significant concern for pain...
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Genetic Variants Associated with Adverse Events after Angiotensin-Converting Enzyme Inhibitor Use: Replication after GWAS-Based Discovery

Lee CJ, Choi B, Pak H, Park JM, Lee JH, Lee SH

Purpose: Angiotensin-converting enzyme inhibitors (ACEIs) are medications generally prescribed for patients with high cardiovascular risk; however, they are suboptimally used due to frequent adverse events (AEs). The present study aimed...
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Long-Term Analysis of Ustekinumab Therapy for Moderate-to-Severe Psoriasis in Korea

Kim Y, Bae KN, Son JH, Shin K, Kim H, Ko HC, Kim MB, Shin BS, Kim B

  • KMID: 2527677
  • Korean J Dermatol.
  • 2022 Mar;60(3):151-158.
Background: Ustekinumab is a humanized monoclonal antibody targeting interleukin (IL)-12 and IL-23. Although popular, data on its long-term efficacy and safety in Korean patients with psoriasis are limited. Objective: To evaluate...
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Assessing Clinical Feasibility and Safety of Percutaneous Dilatational Tracheostomy During Extracorporeal Membrane Oxygenation Support in the Intensive Care Unit

Hong TH, Kim HW, Kim HS, Park S

Purpose: A tracheostomy is often used to wean patients off the ventilator, as it helps maintain extracorporeal membrane oxygenation (ECMO) without sedation. A percutaneous dilatational tracheostomy (PDT) performed in critically...
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A Multi-Center, Double-Blind Randomized Controlled Phase III Clinical Trial to Evaluate the Antiviral Activity and Safety of DA-2802 (Tenofovir Disoproxil Orotate) and Viread (Tenofovir Disoproxil Fumarate) in Chronic Hepatitis B Patients

Kim HJ, Kim JH, Yeon JE, Seo YS, Jang JW, Cho YK, Jang BK, Han BH, Lee C, Lee JH, Yoon JH, Kim KM, Kim MY, Kim DY, Park NH, Cho EY, Lee JS, Lee JW, Kim IH, Song BC, Lee BS, Kwon OS

Background: Tenofovir disoproxil fumarate (TDF, Viread® ) had been used as a standard treatment option of chronic hepatitis B (CHB). This clinical trial was conducted to evaluate the efficacy and...
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Cohort Profile: Gachon Regional Occupational Cohort Study (GROCS)

Lee W, Lee Y, Lee J, Kim U, Han E, Ham S, Choi WJ, Kang SK

Background/Aims The Gachon Regional Occupational Cohort Study (GROCS) is a large-scale longitudinal study of occupational safety and health data (covering Work Environment Monitoring, Workers' Health Surveillance, and Occupational Health Service) conducted...
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Efficacy and Safety of TJP-008 Compared to 2 L PEG with Ascorbate in Colon Cleansing: A Randomized Phase 3 Trial

Koo JS, Byeon JS, Lee BI, Jung 4 SA, Kim TI, Jeen YT

Background/Aims: Polyethylene glycol (PEG)-based bowel preparations are effective cleansing agents for colonoscopy. However, they require relatively large volumes to be used even with agents such as 2 L PEG with...
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Efficacy and Safety of Anti-Tumor Necrosis FactorAlpha Agents for Patients with Intestinal Behcet’s Disease: A Systematic Review and Meta-Analysis

Zhang Q, Ma C, Dong R, Xiang W, Li M, Ma Z, Yang Q

Purpose: Intestinal Behcet’s disease (BD) is a systemic autoimmune disease for which treatment options are limited. As a prospective therapeutic strategy for intestinal BD, anti-tumor necrosis factor-alpha (anti-TNF-α) agents have...
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Factors Influencing Safety Nursing Activities of Nurses at a Nationally Designated Infectious Disease Hospital

Choi SA, Park JY

Purpose: This study investigated patient safety culture, safety knowledge, incident reporting attitude, and safety nursing activities, and determined the factors influencing nurses’ safety nursing activities at a nationally designated infectious...
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Comparison of Clinical Performance and Safety between Domestic New Pull-type Triple-lumen Sphincterotome and Conventional Sphincterotome: A Prospective Multicenter Trial

Park SW, Jang SI, Chung MJ, Cho JH, Bang S

Background/Aims: Sphincterotomes are essential for endoscopic sphincterotomy (EST) and can also be used for cannulation in ERCP. A domestic new pull-type sphincterotome (Optimos™, Taewoong, Goyang, Korea) provides acceptable technical feasibility and...
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