- Non-alcoholic fatty liver diseases: update on the challenge of diagnosis and treatment
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Oh H, Jun DW, Saeed WK, Nguyen MH
- KMID: 2373132
- Clin Mol Hepatol.
- 2016 Sep;22(3):327-335.
- doi: 10.3350/cmh.2016.0049
The prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to be 25-30% of the population, and is the most common cause of elevated liver enzymes in Korea. NAFLD is... -
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- Optimal Hypoxic Preconditioning of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells (hES-MSCs) and Their Characteristics
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Lee SM, Jun DW, Kang HT, Oh JH, Saeed WK, Ahn SB
- KMID: 2515998
- Int J Stem Cells.
- 2021 May;14(2):221-228.
- doi: 10.15283/ijsc20096
Background and Objectives: Hypoxia is frequently used to enhance stem cell function. However, the optimal level of hypoxia for growth and function of human embryonic stem cell-derived mesenchymal stem cells... -
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- Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis
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Lee HY, Jun DW, Kim HJ, Oh H, Saeed WK, Ahn H, Cheung RC, Nguyen MH
- KMID: 2441009
- Korean J Intern Med.
- 2019 Mar;34(2):296-304.
- doi: 10.3904/kjim.2017.194
BACKGROUND/AIMS: A number of clinical trials reported varying effects of cholesterol lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We, therefore, assessed the changes in hepatic steatosis and NAFLD... -
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- Feasibility and Stability of Liver Biopsy before Treatment for Preclinical Nonalcoholic Fatty Liver Studies
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Chae YJ, Jun DW, Saeed WK, Kang HT, Oh JH, Lee SM, Jang K
- KMID: 2440161
- J Korean Med Sci.
- 2019 Jan;34(2):e14.
- doi: 10.3346/jkms.2019.34.e14
BACKGROUND: The heterogeneity of histological findings in preclinical diet-induced nonalcoholic fatty liver disease (NAFLD) animal models is highly challenging. Here, we aimed to evaluate the feasibility and stability of repeated... -
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- The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury
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Chae YJ, Jun DW, Lee JS, Saeed WK, Kang HT, Jang K, Lee JH
- KMID: 2458529
- Gut Liver.
- 2019 Jul;13(4):450-460.
- doi: 10.5009/gnl18235
BACKGROUND/AIMS: For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate. The purpose of this study was to investigate... -
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