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Clinicopathological Significance of SMAD4 Expression in Breast Cancer

Woo JS, Chung MS, Paik SS

PURPOSE: SMAD4 is a member of the SMAD family and acts as a central mediator of transforming growth factor beta signaling. Little is known about SMAD4 expression and its prognostic...
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Pokemon Inhibits Transforming Growth Factor β-Smad4-Related Cell Proliferation Arrest in Breast Cancer through Specificity Protein 1

Chen L, Zhong J, Liu JH, Liao DF, Shen YY, Zhong XL, Xiao X, Ding WJ, Peng XD, Xiong W, Zu XY

PURPOSE: Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study...
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Mesenchymal Smad4 mediated signaling is essential for palate development

Yoon CY, Baek JA, Cho ES, Ko SO

  • KMID: 2328582
  • J Korean Assoc Oral Maxillofac Surg.
  • 2010 Dec;36(6):460-465.
INTRODUCTION: A cleft palate is a common birth defect in humans with an incidence of 1/500 to 1/1,000 births. It appears to be caused by multiple genetic and environmental factors...
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