- Comparative Analysis of Phospholipase D2 Localization in the Pancreatic Islet of Rat and Guinea Pig
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Ryu GR, Kim MJ, Song CH, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH
- KMID: 2285289
- Korean J Physiol Pharmacol.
- 2003 Aug;7(4):211-216.
To examine the localization pattern of phospholipase D2 (PLD2) in the pancreatic islet (the islet of Langerhans) depending on species, we conducted a morphological experiment in the rat and guinea... -
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- Hypoxia Increases β-Cell Death by Activating Pancreatic Stellate Cells within the Islet
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Kim JJ, Lee E, Ryu GR, Ko SH, Ahn YB, Song KH
- KMID: 2513055
- Diabetes Metab J.
- 2020 Dec;44(6):919-927.
- doi: 10.4093/dmj.2019.0181
Background Hypoxia can occur in pancreatic islets in type 2 diabetes mellitus. Pancreatic stellate cells (PSCs) are activated during hypoxia. Here we aimed to investigate whether PSCs within the islet are... -
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- Altered Secretory Pattern of Pancreatic Enzymes and Gastrointestinal Hormones in Streptozotocin-induced Diabetic Rats
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Kim MJ, Ryu GR, Yi SY, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH
- KMID: 1615198
- Korean J Physiol Pharmacol.
- 2002 Dec;6(6):311-317.
This study was performed to investigate the pancreatic exocrine dysfunction in streptozotocin- induced diabetic rats. Changes in pancreatic enzymes secretion and in pancreatic enzymes content were observed. The output and... -
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- Decreased Expression and Induced Nucleocytoplasmic Translocation of Pancreatic and Duodenal Homeobox 1 in INS-1 Cells Exposed to High Glucose and Palmitate
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Ryu GR, Yoo JM, Lee E, Ko SH, Ahn YB, Song KH
- KMID: 2281494
- Diabetes Metab J.
- 2011 Feb;35(1):65-71.
- doi: 10.4093/dmj.2011.35.1.65
BACKGROUND: Type 2 diabetes mellitus (T2DM) is often accompanied by increased levels of circulating fatty acid. Elevations in fatty acids and glucose for prolonged periods of time have been suggested... -
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- Electrophysiological and Morphological Classification of Inhibitory Interneurons in Layer II/III of the Rat Visual Cortex
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Rhie DJ, Kang HY, Ryu GR, Kim MJ, Yoon SH, Hahn SJ, Min DS, Jo YH, Kim MS
- KMID: 1607516
- Korean J Physiol Pharmacol.
- 2003 Dec;7(6):317-323.
Interneuron diversity is one of the key factors to hinder understanding the mechanism of cortical neural network functions even with their important roles. We characterized inhibitory interneurons in layer II/III... -
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- Altered Cholecystokinin-induced Calcium Signal in Streptozotocin-induced Diabetic Rat Pancreatic Acini
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Kim MJ, Ryu GR, Sung JH, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS
- KMID: 1066043
- Korean J Gastroenterol.
- 2003 Dec;42(6):519-526.
BACKGROUND/AIMS: Pancreatic acini of streptozotocin (STZ)-induced diabetic rats release amylase less than normal acini on cholecystokinin (CCK) stimulation. Pancreatic enzyme secretion has been closely related to the intracellular calcium... -
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- Protective Effect of Heme Oxygenase-1 on High Glucose-Induced Pancreatic beta-Cell Injury
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Lee EM, Lee YE, Lee E, Ryu GR, Ko SH, Moon SD, Song KH, Ahn YB
- KMID: 1857502
- Diabetes Metab J.
- 2011 Oct;35(5):469-479.
- doi: 10.4093/dmj.2011.35.5.469
BACKGROUND: Glucose toxicity that is caused by chronic exposure to a high glucose concentration leads to islet dysfunction and induces apoptosis in pancreatic beta-cells. Heme oxygenase-1 (HO-1) has been identified... -
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- The Role of cAMP/PKA Activation on Exendin-4-Induced Cyclin D1 Expression in INS-1 Cell
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Ryu GR, Kang JH, Jang HI, Ko SH, Jeong IK, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS, Kim MJ
- KMID: 2177757
- J Korean Diabetes Assoc.
- 2005 Jul;29(4):295-303.
BACKGROUND: Glucagon-like peptide-1(GLP-1) and exendin-4(EX-4) have been known to induce pancreatic islet proliferation and increases in the betacell mass. Cyclin D1 is a key protein responsible for the entry of... -
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- Immunocytochemical Study on the Change of the Activated T Cells in Peripheral Blood of the Pulmonary Tuberculosis Patients
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Ryu GR, Park CH, Park US, Jeoung PJ, Hwang YS, Lee YJ, Chang GY
- KMID: 2317950
- Tuberc Respir Dis.
- 1995 Dec;42(6):823-830.
BACKGROUND: It has been found that Helper T cells in the peripheral blood are decreased in the cell mediated immunity in the pulmonary tuberculosis But it has not been confirmed... -
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- Transdifferentiation of Enteroendocrine K-cells into Insulin-expressing Cells
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Lee E, Yu JM, Lee MK, Ryu GR, Ko SH, Ahn YB, Moon SD, Song KH
- KMID: 2298053
- Korean Diabetes J.
- 2009 Dec;33(6):475-484.
- doi: 10.4093/kdj.2009.33.6.475
BACKGROUND: Despite a recent breakthough in human islet transplantation for treating type 1 diabetes mellitus, the limited availability of donor pancreases remains a major obstacle. Endocrine cells within the gut... -
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- The Inhibitory Effect of Epicatechin on IL-1beta -induced iNOS Expression and NO Production in RINm5F Cell
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Ryu GR, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH, Kim MJ
- KMID: 2008132
- J Korean Diabetes Assoc.
- 2003 Dec;27(6):456-466.
BACKGROUND: Interleukin-1beta (IL-1beta ) stimulates the expression of inducible nitric oxide synthase (iNOS) and the production of nitric oxide (NO), lead to NO-mediated insulin, which produces cell damage. Within... -
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- The Effect of Epicatechin on the High Glucose-induced TSP-1 Expression and MMP-2 Activity in Rat Vascular Smooth Muscle Cells
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Ryu GR, Kang JH, Hong KJ, Jeong IK, Jang HI, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH, Kim MJ
- KMID: 2200845
- J Korean Soc Endocrinol.
- 2006 Aug;21(4):302-310.
- doi: 10.3803/jkes.2006.21.4.302
BACKGROUND: The incidence of atherosclerosis is well correlated with the progression of type 2 diabetes mellitus. High plasma glucose in uncontrolled diabetic patients evokes many vascular complications such as atherosclerosis.... -
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- Differentiation of Pancreatic beta Cells from Human Pancreatic Duct Cells Derived from a Partial Pancreas Tissue
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Song KH, Kim MM, Lee MK, Ryu GR, Ko SH, Moon SD, Ahn YB, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK, Chin HM
- KMID: 1523012
- J Korean Diabetes Assoc.
- 2007 May;31(3):236-242.
- doi: 10.4093/jkda.2007.31.3.236
BACKGROUND: Despite a recent breakthrough in human islet transplantation for treating diabetes mellitus, the limited availability of insulin-producing tissue is still a major obstacle. This has led to a search... -
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