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The Effect of Angiotensin Converting Enzyme Inhibitor on Chronic Cyclosporine Nephropathyin Salt Depleted Rats

Lee EJ, Lee ES, Hah JH, Kim YJ, Park YH

  • KMID: 2322046
  • J Korean Soc Pediatr Nephrol.
  • 2000 Dec;4(2):127-135.
PURPOSE: Cyclosporine(CsA) is a potent immunosuppressant but the use of CsA is associated with various side effects, especially nephrotoxicity. In the kidney, salt depletion activates the renin-angiotensin-aldosteron(RAS) system and accentuates...
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