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Autism-Like Behavioral Phenotypes in Mice Treated with Systemic N-Methyl-D-Aspartate

Jym Adil K, Gonzales EL, Remonde CG, Boo KJ, Jeon SJ, Shin CY

Autism spectrum disorder (ASD) having core characteristics of social interaction problems and repetitive behaviors and interests affects individuals at varying degrees and comorbidities, making it difficult to determine the precise...
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Behavioral Deficits in Adolescent Mice after Sub-Chronic Administration of NMDA during Early Stage of Postnatal Development

Adil KJ, Remonde CG, Gonzales EL, Boo KJ, Kwon KJ, Kim DH, Kim HJ, Cheong JH, Shin CY, Jeon SJ

Neurodevelopmental disorders are complex conditions that pose difficulty in the modulation of proper motor, sensory and cognitive function due to dysregulated neuronal development. Previous studies have reported that an imbalance...
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Hycanthone Inhibits Inflammasome Activation and Neuroinflammation-Induced Depression-Like Behaviors in Mice

Boo KJ, Gonzales EL, Remonde CG, Seong JY, Jeon SJ, Park YM, Ham BJ, Shin CY

Despite the various medications used in clinics, the efforts to develop more effective treatments for depression continue to increase in the past decades mainly because of the treatment-resistant population, and...
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