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Inhibition of miR-146a-5p and miR-8114 in Insulin-Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa

Su S, Zhao Q, Dan L, Lin Y, Li X, Zhang Y, Yang C, Dong Y, Li X, Regazzi R, Sun C, Chu X, Lu H

Background: Chronic exposure to elevated levels of saturated fatty acids results in pancreatic β-cell senescence. However, targets and effective agents for preventing stearic acid-induced β-cell senescence are still lacking. Although...
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