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Focal Ligamentum Flavum Hypertrophy with Ochronotic Deposits: An Unusual Cause for Neurogenic Claudication in Alkaptonuria

Reddy R, Vijayasaradhi M, Biswal D

Neurogenic claudication resulting from focal hypertrophy of the ligamentum flavum in the lumbar spine due to ochronotic deposits has not been reported till date. The authors discuss one such case...
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SARS-CoV-2 in the Prostate: Immunohistochemical and Ultrastructural Studies

Reddy R, Farber N, Kresch E, Seetharam D, Diaz P, Ramasamy R

The novel coronavirus SARS-CoV-2 was discovered in 2019 and has proven to be a significant public health challenge. While viruses from the coronavirus family have been established as causes of respiratory...
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7T Magnetic Resonance Imaging Quantification of Brain Glutamate in Acute Ischaemic Stroke

Nicolo JP, Moffat B, Wright DK, Sinclair B, Neal A, Lui E, Desmond P, Glarin R, Davis KA, Reddy R, Yan B, O’Brien TJ, Kwan P

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Transforming growth factor-beta and liver injury in an arginine vasopressin-induced pregnant rat model

Govender N, Ramdin S, Reddy R, Naicker T

Objective: Approximately 30% of preeclamptic pregnancies exhibit abnormal liver function tests. We assessed liver injury-associated enzyme levels and circulating transforming growth factor beta (TGF-β) levels in an arginine vasopressin (AVP)-induced...
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Comparison of Intratesticular Testosterone between Men Receiving Nasal, Intramuscular, and Subcutaneous Pellet Testosterone Therapy: Evaluation of Data from Two Single-Center Randomized Clinical Trials

Diaz P, Reddy R, Blachman-Braun R, Zucker I, Dullea A, Gonzalez DC, Kresch E, Ramasamy R

Purpose Testosterone replacement therapy (TRT) can potentially cause decreased spermatogenesis and subsequent infertility. Recent studies have suggested that 17-hydroxyprogesterone (17-OHP) is a reliable surrogate for intratesticular testosterone (ITT) that is essential...
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Algorithms for Predicting the Probability of Azoospermia from Follicle Stimulating Hormone: Design and Multi-Institutional External Validation

Tradewell MB, Cazzaniga W, Pagani RL, Reddy R, Boeri L, Kresch E, Morgantini LA, Ibrahim E, Niederberger C, Salonia A, Ramasamy R

Purpose: To predict the probability of azoospermia without a semen analysis in men presenting with infertility by developing an azoospermia prediction model. Materials and Methods: Two predictive algorithms were generated, one...
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