- Vasopressin and Vasopressin Receptor Antagonists
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Oh YK
- KMID: 2052306
- Electrolyte Blood Press.
- 2008 Jun;6(1):51-55.
- doi: 10.5049/EBP.2008.6.1.51
Vasopressin, a neurohypophyseal peptide hormone, is the endogenous agonist at V1a, V1b, and V2 receptors. The most important physiological function of vasopressin is the maintenance of water homeostasis through interaction... -
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- The Role of V2 Receptor Antagonists in the Treatment of Hyponatremia
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Palmer BF
- KMID: 2168394
- Electrolyte Blood Press.
- 2013 Jun;11(1):1-8.
- doi: 10.5049/EBP.2013.11.1.1
No abstract available. -
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- Efficacy of Vaptans for Management of Ascites in Patients with Liver Cirrhosis
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Choe WH, Lee JS
- KMID: 2264193
- Korean J Med.
- 2012 Jan;82(1):22-31.
Ascites is the most common complication of liver cirrhosis, but its pharmacological management is unsatisfactory in some patients because of a lack of response to treatment with conventional diuretics. Patients... -
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- V2 Receptor Antagonist; Tolvaptan
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Yi JH, Shin HJ, Kim HJ
- KMID: 2168384
- Electrolyte Blood Press.
- 2011 Dec;9(2):50-54.
- doi: 10.5049/EBP.2011.9.2.50
Hyponatremia is the most common electrolyte disorder in hospitalized patients. Many studies documented that it was related to increased morbidity and mortality in patients with congestive heart failure, liver cirrhosis,... -
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- A Case of Hyponatraemic Seizure Following Terlipressin Therapy for a Variceal Hemorrhage in a Patient with Liver Cirrhosis
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Kim JH, Kim JK, Mun SY, Choi CJ, Park HM, Jeong YS, Kang JG
- KMID: 2269243
- Korean J Med.
- 2014 Sep;87(3):323-327.
- doi: 10.3904/kjm.2014.87.3.323
Terlipressin has splanchnic vasoconstrictive effects, and is generally used for the management of gastroesophageal variceal bleeding secondary to liver cirrhosis. Terlipressin is a synthetic arginine vasopressin (AVP) analog containing a... -
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- New insights into the transcriptional regulation of aquaporin-2 and the treatment of X-linked hereditary nephrogenic diabetes insipidus
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Jung HJ, Kwon TH
- KMID: 2451864
- Kidney Res Clin Pract.
- 2019 Jun;38(2):145-158.
- doi: 10.23876/j.krcp.19.002
The kidney collecting duct (CD) is a tubular segment of the kidney where the osmolality and final flow rate of urine are established, enabling urine concentration and body water homeostasis.... -
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- Osmotic Demyelination Syndrome Resulting from an Unexpected Response to Tolvaptan in a Patient with Heart Failure
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Kim K, Kang MG, Park JR, Hwang JY, Kwak CH
- KMID: 2376945
- Korean J Med.
- 2017 Feb;92(1):62-65.
- doi: 10.3904/kjm.2017.92.1.62
Hyponatremia is commonly encountered in patients with heart failure and has a poor prognosis. Tolvaptan, a novel selective vasopressin V2 receptor blocker, has received attention as an effective drug for... -
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- Clinical Application of V2 Receptor Antagonists
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Oh IH, Kim GH
- KMID: 2269331
- Korean J Med.
- 2014 Jun;86(6):686-694.
Hyponatremia results from a relative excess of total body water compared with the sodium content. Except for primary polydipsia, vasopressin activation plays a major role in pathogenesis of water retention.... -
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- Edematous Hyponatremia Treated with Tolvaptan in a Patient with Amyotrophic Lateral Sclerosis
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Kim GH
- KMID: 2401151
- Electrolyte Blood Press.
- 2017 Dec;15(2):37-41.
- doi: 10.5049/EBP.2017.15.2.37
Amyotrophic lateral sclerosis (ALS) patients rarely present with either syndrome of inappropriate antidiuretic hormone secretion or generalized edema. Tolvaptan is a selective vasopressin V2 receptor antagonist that produces effective aquaresis,... -
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- Congenital nephrogenic diabetes insipidus with end-stage renal disease
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Ryu HH, Chung JH, Shin BC, Kim HL
- KMID: 2160694
- Korean J Intern Med.
- 2015 Mar;30(2):259-261.
- doi: 10.3904/kjim.2015.30.2.259
No abstract available. -
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- Management of Chronic Asymptomatic Hyponatremia
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Bae EH
- KMID: 2305753
- Korean J Med.
- 2011 Jan;80(1):15-19.
Hyponatremia is a common clinical problem in hospitalized patients and nursing home residents. It may also occur in healthy athletes after endurance exercise. The majority of patients with hyponatremia are... -
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- Recent Advances in the Management of Autosomal Dominant Polycystic Kidney Disease
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Park H, Hwang YH
- KMID: 2269025
- Korean J Med.
- 2015 Aug;89(2):169-178.
- doi: 10.3904/kjm.2015.89.2.169
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It is characterized by the dysregulated growth of kidney cysts, resulting in end-stage kidney failure. By identifying... -
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- Increases of cAMP Production and Urinary cAMP Excretion by Oxytocin in the Inner Medullary Collecting Duct(IMCD)
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Na KY, Jeon US, Joo KW, Huh WS, Lee JG, Jung WK, Kim KS, Kim YS, Ahn C, Han JS, Kim SG, Lee JS
- KMID: 2254583
- Korean J Nephrol.
- 2000 Jan;19(1):58-63.
Oxytocin, like vasopressin, has been known to act in the IMCD by the activation of adenylyl cyclase through V2 receptor, but the exact mechanism of its action remains to be... -
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- Analysis of Vasopressin Receptor Type 2(A VPR2) Gene in a Pedigree with Congenital Nehrogenic Diabetes Insipidus: Identification of a Fanily with R 202C Mutation in A VPR 2 Gene
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Park HW, Park JD, Kim HS, Kim HJ, Lee YK, Ha IS, Cheong HI, Choi Y
- KMID: 2001758
- J Korean Soc Pediatr Nephrol.
- 1999 Oct;3(2):209-216.
Curschmann's spirals morphologically similar to those seen in sputum were found in cervico-vaginal smears of six patients ranged from 28 to 40 years of age, during 18 months from January.... -
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- Oxytocin produces thermal analgesia via vasopressin-1a receptor by modulating TRPV1 and potassium conductance in the dorsal root ganglion neurons
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Han RT, Kim HB, Kim YB, Choi K, Park GY, Lee PR, Lee J, Kim HY, Park CK, Kang Y, Oh SB, Na HS
- KMID: 2410107
- Korean J Physiol Pharmacol.
- 2018 Mar;22(2):173-182.
- doi: 10.4196/kjpp.2018.22.2.173
Recent studies have provided several lines of evidence that peripheral administration of oxytocin induces analgesia in human and rodents. However, the exact underlying mechanism of analgesia still remains elusive. In... -
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- The Anti-Inflammatory Effect of Arginine-Vasopressin on Lipopolysaccharide-Induced IkappaBalpha/Nuclear Factor-kappaB Cascade
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Park J, Eo EY, Lee KH, Park JS, Lee JH, Yoo CG, Lee CT, Cho YJ
- KMID: 2227639
- Korean J Crit Care Med.
- 2015 Aug;30(3):151-157.
- doi: 10.4266/kjccm.2015.30.3.151
BACKGROUND: Arginine vasopressin (AVP) is widely used as a vasopressor agent. Some recent studies have suggested that AVP may exert an immunomodulatory effect. However, the mechanism about the anti-inflammatory effect... -
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- New Mutation Site in Vasopressin V2 Receptor Gene in a Family with Congenital Nephrogenic Diabetes Incipidus
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Lee SH, Choi CH, Park SH, Choi YS, Kim JG, Ha SW, Kim BW
- KMID: 1540027
- J Korean Soc Endocrinol.
- 2000 Mar;15(1):97-106.
BACKGROUND: Congenital nephrogenic diabetes insipidus (NDI) is a rare inherited disorder, in which two different hereditary forms, X-linked and autosomal recessive traits, have been identified. The X-linked recessive form, mostly... -
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- The Effect of Oxytocin on Subcellular Localization of Aquaporin-2 in Rat Kidney: an Ultrastructural Immunocytochemical Study
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Kim JY, Kim WY, Han KH, Kim J, Kim GH, Han JS
- KMID: 2254306
- Korean J Nephrol.
- 2004 Jul;23(4):547-558.
BACKGROUND: The aquaporin-2 (AQP2) water channel is mainly located in the apical plasma membrane of epithelial cells in the connecting tubule and collecting ducts, but there has been some evidence... -
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- Congenital Nephrogenic Diabetes Insipidus Presented with Bilateral Hydronephrosis: Genetic Analysis of V2R Gene Mutations
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Yoo TH, Ryu DR, Song YS, Lee SC, Kim HJ, Kim JS, Choi HY, Kang SW
- KMID: 1715882
- Yonsei Med J.
- 2006 Feb;47(1):126-130.
- doi: 10.3349/ymj.2006.47.1.126
Most cases of hydronephrosis are caused by urinary tract obstruction. However, excessive polyuric syndrome rarely gives rise to non-obstructive hydronephrosis, megaureter, and a distended bladder. The authors report here on... -
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