- Effect of Ga2 gene mutation on the Expression of Thyrotropin-Releasing Hormone ( TRH ) Receptor Gene in GH3 Cells
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Park SJ, Yang IM, Ryu JH, Chung JH, Jung JC, Ko KC, Kim YS, Choi YK
- KMID: 1999281
- J Korean Soc Endocrinol.
- 1997 Sep;12(3):357-363.
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- Characteristics of Acromegalic Patients According to GH Pulse Frequency
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Lee GC, Yang IM, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK
- KMID: 2080482
- Korean J Med.
- 1997 Apr;52(4):437-444.
OBJECTIVES: Pulsatile secretion of GH are present in acromegalics and normal men. GH concentration profiles in patients with acromegaly are characterized by rapid GH pulsatility and high interpulse concentrations. There... -
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- Discrepancy between in vitro and in vivo effect of Galphas gene mutation on the mRNA expression of TRH receptor
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Park S, Yang I, Yim S, Chung J, Jung J, Ko K, Kim Y, Choi Y
- KMID: 2071530
- Korean J Physiol Pharmacol.
- 1998 Feb;2(1):101-108.
We investigated the effect of alpha-subunit of the stimulatory GTP-binding protein (Galphas) gene mutation on the expression of the thyrotropin-releasing hormone (TRH) receptor (TRH-R) gene in GH3 cells and in growth hormone (GH)-secreting... -
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- Expression of TRH Receptor Gene in GH-Secreting Piruitary Adenomas
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Yang IM, Park SJ, Ryu JW, Chung JH, Ryu MS, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK
- KMID: 1999280
- J Korean Soc Endocrinol.
- 1997 Sep;12(3):349-356.
Background: To test the hypothesis that Galphas gene mutation may suppress the expression of TRH-R gene, we investigated whether hTRH-R gene expression is lower in human GH-secreting pituitary adenomas with... -
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- Thyrotropin-releasing Hormone(TRH) Receptor Gene Expression in GH3 Cells Permanently Transfected with a Mutant Gs alpha Gene
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Park SJ, Yang IM, Yim SV, Chung JH, Jung JC, Ko KC, Kim YS, Choi YK
- KMID: 1540023
- J Korean Soc Endocrinol.
- 2000 Mar;15(1):46-54.
BACKGROUND: Gs alpha gene mutation, that constitutively increases intracellular cAMP, is found in some acromegalic patients. It was demonstrated that increased intracellular cAMP levels suppress the expression of rat TRH... -
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