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A number of studies have demonstrated that 5-hydroxytryptamine (5-HT) can induce muscle contraction or relaxation response and enhance secretion in the gastrointestinal tract via a multiplicity of 5-HT receptor subtypes....
Simonic(1988) have investigated that hypothermic effect of oholinornimetics is mediated through an activation of muscarine cholinergic receptors. And also, Yamada(1987) injected trytamine into the lateral cerebroventricle in mice and observed...
PURPOSE: The purpose of this study is to investigate in vitro the effects of serotonin on the rat detrusor. In particular, this study examines what drugs inhibit the serotonin-induced detrusor...
Lim YC, Koh JT, Kim HJ, Lee S, Jang AS, Yang SW, Seo JP, Choi JB, Kook YJ
KMID: 1990073
Korean J Nephrol.
1999 Mar;18(2):211-218.
It has been known that central tryptaminergic system is closely related with the regulation of renal function, and that central 5-HT1 receptors mediate diuresis and natriuresis, whereas central 5-HT2 and...
PCPA is a drug which depletes serotonin by inhibiting tryptophan hydroxylase activity.
Recent evidence indicates that the ascending cholinergic projection from the basal forebrain and ascending serotonergic projections from the brain...