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Molecular checkpoints controlling natural killer cell activation and their modulation for cancer immunotherapy

Kwon HJ, Kim N, Kim HS

Natural killer (NK) cells have gained considerable attention as promising therapeutic tools for cancer therapy due to their innate selectivity against cancer cells over normal healthy cells. With an array...
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Selective Expansion of Natural Killer Cells from Peripheral Blood Mononuclear Cells by K562 Cell Line and IL-2

Cho D, Shin SW, Park JS, Kang HK, Kim SK, Pham TN, Zhu XW, Shin MG, Suh SP, Ryang DW, Nam JH, Kim YJ, Lee JJ

BACKGROUND: Several attempts have been made to expand human NK cells from peripheral blood mononuclear cells (PBMCs). This study examined the selective expansion of NK cells using interleukin 2 (IL-2)...
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