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Effects of Dexamethasone on expressions of IFN-gamma and IL-4 by PBMCs in response to IL-12

Heo SH, Lee SB, Chae GT

  • KMID: 2053859
  • Korean Lepr Bull.
  • 2002 Dec;35(2):3-12.
Dexamethasone is a widely used anti-inflammatory agent for a broad spectrum of diseases. The effectiveness of this agent is thought to be due to the capacity to modulate cytokine production...
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Regulation of Cytokine Gene Expression in Nasal Polyp

Kim CN, Hong SK, Kim MJ, Hong YS

  • KMID: 2275867
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Feb;45(2):137-143.
BACKGROUND AND OBJECTIVES: The etiology and pathogenesis of nasal polyp are still ill-defined and have been debated for many years. Recently, the identification and localization of mRNA of cytokines, chemokines,...
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mRNA Expression and RNA Editing (2451 C-to-U) of IL-12 Receptor beta2 in Adult Atopic Patients

Kim EJ, Lee WM, Ha JS, Ryoo NH, Jeon DS, Kim JR

Interleukin (IL)-12 activates T helper (Th) 1 cells to produce interferon (IFN)-gamma which inhibits atopic inflammation. IL-12 acts through interaction with its receptor, especially beta2 subunit. In several studies, the...
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