- Usefulness of Real-Time Quantitative Microvascular Ultrasonography for Differentiation of Graves’ Disease from Destructive Thyroiditis in Thyrotoxic Patients
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Baek HS, Park JY, Jeong CH, Ha J, Kang MI, Lim DJ
- KMID: 2529224
- Endocrinol Metab.
- 2022 Apr;37(2):323-332.
- doi: 10.3803/EnM.2022.1413
Background: Microvascular ultrasonography (MVUS) is a third-generation Doppler technique that was developed to increase sensitivity compared to conventional Doppler. The purpose of this study was to compare MVUS with conventional... -
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- The Clinical Outcomes of Different First-Line EGFR-TKIs Plus Bevacizumab in Advanced EGFR-Mutant Lung Adenocarcinoma
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Huang YH, Hsu KH, Chin CS, Tseng JS, Yang TY, Chen KC, Su KY, Yu SL, Chen JJ, Chang GC
- KMID: 2528213
- Cancer Res Treat.
- 2022 Apr;54(2):434-444.
- doi: 10.4143/crt.2021.671
Purpose The aim of this study was to investigate the efficacy of various epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) plus bevacizumab in advanced EGFR-mutant lung adenocarcinoma patients. Materials and Methods From... -
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- Bioaerosol Exposure and in vitro Activation of Toll-like Receptors in a Norwegian Waste Sorting Plant
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Eriksen E, Graff P, Pedersen I, Straumfors A, Afanou AK
- KMID: 2528012
- Saf Health Work.
- 2022 Mar;13(1):9-16.
- doi: 10.1016/j.shaw.2021.09.002
Background The global shift toward greener societies demands new technologies and work operations in the waste-management sector. However, progressive industrial methods do not necessarily consider workers’ health. This study characterized workers'... -
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- Individualized Treatment for Patients With Familial Hypercholesterolemia
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Tada H, Takamura M, Kawashiri Ma
- KMID: 2525236
- J Lipid Atheroscler.
- 2022 Jan;11(1):39-54.
- doi: 10.12997/jla.2022.11.1.39
Familial hypercholesterolemia (FH) is one of the most common and, therefore, important inherited disorders in preventive cardiology. This disease is mainly caused by a single pathogenic mutation in the low-density... -
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- Anti-nociceptive and anti-inflammatory activities of the essential oil isolated from Cupressus arizonica Greene fruits
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Fakhri S, Jafarian S, Majnooni MB, Farzaei MH, Mohammadi-Noori E, Khan H
- KMID: 2524645
- Korean J Pain.
- 2022 Jan;35(1):33-42.
- doi: 10.3344/kjp.2022.35.1.33
Background: Cupressus arizonica Greene is a coniferous tree with great importance in fragrance and pharmaceutical industries. Essential oils from C. arizonica (EC) have shown potential antioxidant, and anti-microbial activities. This... -
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- The role of basolateral amygdala orexin 1 receptors on the modulation of pain and psychosocial deficits in nitroglycerin-induced migraine model in adult male rats
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Askari-Zahabi K, Abbasnejad M, Kooshki R, Raoof M, Esmaeili-Mahani S, Pourrahimi AM, Zamyad M
- KMID: 2524643
- Korean J Pain.
- 2022 Jan;35(1):22-32.
- doi: 10.3344/kjp.2022.35.1.22
Background: Migraine headaches have been associated with sensory hyperactivity and anomalies in social/emotional responses. The main objective of this study was to evaluate the potential involvement of orexin 1 receptors... -
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- The optimal anti-phospholipase A2 receptor cutoff for the diagnosis of idiopathic membranous nephropathy: a single-center retrospective study
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Li C, Li P, Guo W, Chen L, Li J, Wang R, Chen B
- KMID: 2524251
- Korean J Intern Med.
- 2022 Jan;37(1):154-166.
- doi: 10.3904/kjim.2020.366
Background/Aims: Anti-phospholipase A2 receptor (PLA2R) autoantibody is the main biomarker of idiopathic membranous nephropathy (IMN). We aimed to find a new cutoff value of anti-PLA2R for patients with IMN and... -
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- The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE−/−FXR−/− Mice
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Lee Y, Kim BR, Kang GH, Lee GJ, Park YJ, Kim H, Jang HC, Choi SH
- KMID: 2523493
- Endocrinol Metab.
- 2021 Dec;36(6):1243-1253.
- doi: 10.3803/EnM.2021.1100
Background: Farnesoid X receptor (FXR), a bile acid–activated nuclear receptor, is a potent regulator of glucose and lipid metabolism as well as of bile acid metabolism. Previous studies have demonstrated... -
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- Clinical Value of Serum Mitochondria-Inhibiting Substances in Assessing Renal Hazards: A Community-Based Prospective Study in Korea
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Choi HS, Kim JT, Lee HK, Park WH, Kim Pak Y, Lee SW
- KMID: 2523498
- Endocrinol Metab.
- 2021 Dec;36(6):1298-1306.
- doi: 10.3803/EnM.2021.1226
Background: Mitochondrial dysfunction is strongly associated with several kidney diseases. However, no studies have evaluated the potential renal hazards of serum mitochondria-inhibiting substance (MIS) and aryl hydrocarbon receptor ligand (AhRL)... -
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- Dietary glucosinolates inhibit splenic inflammation in high fat/cholesterol diet-fed C57BL/6 mice
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Gu H, Gwon MH, Kim SM, Yun JM
- KMID: 2522658
- Nutr Res Pract.
- 2021 Dec;15(6):798-806.
- doi: 10.4162/nrp.2021.15.6.798
BACKGROUND/OBJECTIVES: Obesity is associated with chronic inflammation. The spleen is the largest organ of the lymphatic system and has an important role in immunity. Obesity-induced inflammatory responses are triggered by Toll-like... -
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- Cooperative Subtype Switch of Thyroid Hormone Receptor and Nuclear Receptor Corepressor Related Epithelial–Mesenchymal Transition in Papillary Thyroid Cancer
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Jeong S, Lee SG, Kim H, Lee G, Park S, Kim IK, Lee J, Jo YS
- KMID: 2522920
- Int J Thyroidol.
- 2021 Nov;14(2):152-169.
- doi: 10.11106/ijt.2021.14.2.152
Background and Objectives: Although thyroid hormones affect human cancer progression, the regulatory mechanism of thyroid hormone receptors in carcinogenesis has not been elucidated. This study aimed to evaluate the expression... -
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- Practical Review of Biologics in Chronic Rhinosinusitis With Nasal Polyps
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Lee KI, Ryu G, Yoo SH, Kim YM, Mo JH, Shin SH
- KMID: 2522781
- J Rhinol.
- 2021 Nov;28(3):131-140.
- doi: 10.18787/jr.2021.00382
Well-characterized in chronic rhinosinusitis, type 2 inflammation is frequently associated with nasal polyps, comorbid asthma, and nonsteroidal anti-inflammatory drug hypersensitivity. Despite medical and surgical treatment, it recurs in a significant... -
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- Role of the TAS2R38 Bitter Taste Receptor Gene Single Nucleotide Polymorphism in Patients With Taste Disorders
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Kang BJ, Park JW, Geum SY, Kim UK, Shin SH, Ye MK
- KMID: 2522830
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2021 Nov;64(11):800-805.
- doi: 10.3342/kjorl-hns.2021.00486
Background and Objectives Several studies have shown that three single nucleotide polymorphisms (SNPs) in the TAS2R38 gene demonstrate a strong association with the ability to sense the bitter taste of... -
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- Upregulation of Toll-like Receptor 2 in Dental Primary Afferents Following Pulp Injury
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Lee PR, Lee JH, Park JM, Oh SB
- KMID: 2522146
- Exp Neurobiol.
- 2021 Oct;30(5):329-340.
- doi: 10.5607/en21018
Pulpitis (toothache) is a painful inflammation of the dental pulp and is a prevalent problem throughout the world. This pulpal inflammation occurs in the cells inside the dental pulp, which... -
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- NaHCO 3- and NaCl-Type Hot Springs Enhance the Secretion of Inflammatory Cytokine Induced by Polyinosinic-Polycytidylic Acid in HaCaT Cells
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Park SH, Jung BY, Lee SY, Yu DS, Woo SY, Yun ST, Lee JT, Kim JW, Lee YB
- KMID: 2519929
- Ann Dermatol.
- 2021 Oct;33(5):440-447.
- doi: 10.5021/ad.2021.33.5.440
Background: Hot springs have been traditionally used as an alternative treatment for a wide range of diseases, including rheumatoid arthritis, bronchial asthma, diabetes, hypertension, psoriasis and atopic dermatitis. However, the... -
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- Prognostic Significance of Epidermal Growth Factor Receptor Expression in Distant Metastatic Melanoma from Primary Cutaneous Melanoma
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Lee KH, Suh HY, Lee MW, Lee WJ, Chang SE
- KMID: 2519928
- Ann Dermatol.
- 2021 Oct;33(5):432-439.
- doi: 10.5021/ad.2021.33.5.432
Background: Epidermal growth factor receptor (EGFR) is overexpressed in many cancers. However, EGFR expression in melanoma and its role are conflicting. Objective: This study aimed to evaluate EGFR expression in... -
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- Modern diagnostic capabilities of neonatal screening for primary immunodeficiencies in newborns
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Khalturina EO, Degtyareva ND, Bairashevskaia AV, Mulenkova AV, Degtyareva AV
- KMID: 2520826
- Clin Exp Pediatr.
- 2021 Oct;64(10):504-510.
- doi: 10.3345/cep.2020.01270
Population screening of newborns is an extremely important and informative diagnostic approach that allows early identification of babies who are predisposed to the development of a number of serious diseases.... -
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- Prenatal Diagnosis of an Ascending Aortic Aneurysm Inherited from the Father: A Case Report of Loeys-Dietz Syndrome Type 1
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Sim YK, Lee DH, Kim JK, Chae HS, Lee JH, Jeong YJ
- KMID: 2522533
- Perinatology.
- 2021 Sep;32(3):151-155.
- doi: 10.14734/PN.2021.32.3.151
Inherited aortic aneurysms are very rare during fetal life. If an aortic aneurysm is seen on prenatal ultrasound, the differential diagnosis of hereditable connective tissue disorders, such as Loeys-Dietz syndrome,... -
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- Platelet Reactivity Was Not Associated with Infarct Size after Primary Percutaneous Coronary Intervention
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Park S, Yun KH, Cho JY, Lee SY
- KMID: 2520347
- Chonnam Med J.
- 2021 Sep;57(3):204-210.
- doi: 10.4068/cmj.2021.57.3.204
Potent antiplatelet therapy after primary percutaneous coronary intervention (PCI) has the potential to reduce infarct size. This study analyzed the association between on-treatment platelet reactivity and myocardial infarct size in... -
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- Diagnostic Performance of Erythropoietin and Erythropoietin Receptors Levels in Children with Attention Deficit Hyperactivity Disorder
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Gungor M, Kurutas EB, Oner E, Unsal V, Altun H, Yalin AE, Yalin S, Bozkus O, Sahin N
- KMID: 2519561
- Clin Psychopharmacol Neurosci.
- 2021 Aug;19(3):530-536.
- doi: 10.9758/cpn.2021.19.3.530
Objective: Attention deficit hyperactivity disorder (ADHD) is a heterogeneous, highly heritable, a common childhood neurobehavioural disorder resulting from complex gene-gene and gene-environment interactions. The erythropoietin (Epo)/erythropoietin receptors (EpoR) system turned... -
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