Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

2,604 results
Display

Intravenous Administration of Toll-Like Receptor Inhibitory Peptide 1 is Effective for the Treatment of Systemic Lupus Erythematosus in a Mus musculus Model

Baek WY, Lee SM, Lee SW, Son IO, Choi S, Suh CH

Objective Systemic lupus erythematosus (SLE) is a common chronic autoimmune inflammatory disease. According to recent studies, signaling through Toll-like receptor (TLR) protein, which promotes the production of inflammatory cytokines, leads...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Vanillin oxime inhibits lung cancer cell proliferation and activates apoptosis through JNK/ERK-CHOP pathway

Shen J, Su Z

Lung cancer despite advancement in the medical field continues to be a major threat to human lives and accounts for a high proportion of fatalities caused by cancers globally. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Profiling of T Cell Receptor β-Chain Complimentary Determining Regions 3 Repertoire in Subarachnoid Hemorrhage Patients Using High-Throughput Sequencing

Kim BJ, Ahn JH, Youn DH, Jeon JP

Objective : The adaptive immune response following subarachnoid hemorrhage (SAH) is not well understood. We evaluated and compared the T cell receptor (TCR) immune repertoire of good-grade and poor-grade SAH...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Incidence and Risk of Venous Thromboembolism in Bisphosphonates and Selective Estrogen Receptor Modulators Treatment in Korea

Park SY, Kim SH, Kim TY, Lee YK, Ha YC, Jang S, Ahn SH, Kim HY

Background: Selective estrogen receptor modulators (SERMs) were associated with an increased risk of venous thromboembolism (VTE) due to the estrogen effect. In this study, we investigated the effect of SERMs...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Optimization of adipogenic differentiation conditions for canine adipose-derived stem cells

Kim JY, Park EJ, Kim SM, Lee HJ

Background: Canine adipose-derived stem cells (cADSCs) exhibit various differentiation properties and are isolated from the canine subcutaneous fat. Although cADSCs are valuable as tools for research on adipogenic differentiation, studies...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors

Paudel S, Kim E, Zhu A, Acharya S, Min X, Cheon SH, Kim KM

In this study, we determined the effect of 24 different synthetic 4-benzylpiperidine carboxamides on the reuptake of serotonin, norepinephrine, and dopamine (DA), and characterized their structure–activity relationship. The compounds with...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
RNA interference mediated suppression of TRPV6 inhibits the progression of prostate cancer in vitro by modulating cathepsin B and MMP9 expression

Kim DY, Kim SH, Yang EK

Purpose: The transient receptor potential vanilloid 6 (TRPV6) channel is overexpressed in prostate cancer and its silencing is known to inhibit the growth of LNCaP cells. However, the role of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease

Song JH, Kim GT, Park KH, Park WJ, Park TS

  • KMID: 2517155
  • Biomol Ther.
  • 2021 Jul;29(4):373-383.
Atherosclerosis is the deposition of plaque in the main arteries. It is an inflammatory condition involving the accumulation of macrophages and various lipids (low-density lipoprotein [LDL] cholesterol, ceramide, S1P). Moreover,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
4-CMTB Ameliorates Ovalbumin-Induced Allergic Asthma through FFA2 Activation in Mice

Lee JH, Im DS

Free fatty acid receptor 2 (FFA2, also known as GPR43), a G-protein-coupled receptor, has been known to recognize short-chain fatty acids and regulate inflammatory responses. FFA2 gene deficiency exacerbated disease...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis

Son JH, Lee JU, Chin S, Go ES, Park JS, Shin HK, Chang HS, Park JS, Park CS

Background/Aims: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a major regulator of Wnt signaling, which is involved in fibroblast dysfunction. Because its role has not been evaluated in idiopathic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of a novel point mutation in DAX-1 gene in a patient with adrenal hypoplasia congenita

Choi HS, Kwon A, Chae HW, Suh J, Song KC, Lee JS, Kim HS

X-linked adrenal hypoplasia congenita caused by a mutation in NR0B1/DAX-1 is a rare inherited disorder. Patients with adrenal hypoplasia congenita are usually diagnosed with primary adrenal insufficiency in infancy or...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Implications of the simple chemical structure of the odorant molecules interacting with the olfactory receptor 1A1

Oh SJ

G protein–coupled receptors (GPCRs), including olfactory receptors, account for the largest group of genes in the human genome and occupy a very important position in signaling systems. Although olfactory receptors,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Cipadesin Limonoid and a Tirucallane Triterpene from the Fruit of Sandoricum koetjape and their Inhibitory Properties against Receptor Tyrosine Kinases

Rachmadhaningtiyas DA, Heliawati L, Hermawati E, Syah YM

A new cipadesin limonoid, i.e. 3-epi-cipadonoid C (1), and a new tirucallane triterpene, i.e. hispidol B 3-palmitate (3), have been isolated from the seeds and fruit peels extract of Sandoricum...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Association of Circulating Brain-Derived Neurotrophic Factor with Cognition among Adult Obese Population

Katuri RB, Gaur GS, Sahoo JP, Bobby Z, Shanmugavel K

Background: Obesity has a strong association with the risk of developing cognitive impairment and dementia at a later age. Brain-derived neurotrophic factor (BDNF) and its receptor appear to be important...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
West syndrome with hyperkinesia and cortical visual impairment: A case report of GRIN1 encephalopathy

Choi SA, Kim YO

West syndrome (WS) presenting with infantile spasms, developmental delay, and hypsarrhythmia has genetic etiology in some patients. Movement disorders or visual impairment that share genetic underpinnings with infantile spasms can...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Receptor-Mediated Muscle Homeostasis as a Target for Sarcopenia Therapeutics

Yoon JH, Kwon KS

Sarcopenia is a disease characterized by age-related decline of skeletal muscle mass and function. The molecular mechanisms of the pathophysiology of sarcopenia form a complex network due to the involvement...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Characteristics of HER2-Positive Breast Cancer according to HER2 2+/ Low or 3+/High Classification by Immunohistochemistry Assay: Study of 205 Cases Treated in a Single Center

Lee C, Park I, Kim J, Cho H, Yang K, Lee Y, Park K, Kim J, Shin Y, Gwak G

Purpose: To investigate the characteristics of HER2-positive breast cancer according to HER2 low (2+) or high (3+) classification using immunohistochemistry (IHC). Methods: Data were collected from 205 HER2-positive breast cancer...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Toll-like Receptor 2 in Autoimmune Inflammation

Marks KE, Cho K, Stickling C, Reynolds JM

TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Gut-Brain Connection: Microbiome, Gut Barrier, and Environmental Sensors

Gwak MG, Chang SY

The gut is an important organ with digestive and immune regulatory function which consistently harbors microbiome ecosystem. The gut microbiome cooperates with the host to regulate the development and function...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Netrin-1/receptors regulate the pathogenesis in Parkinson’s diseases

Ahn EH, Kang SS, Ye K

The netrins and their receptors (deleted in colorectal cancer [DCC] and unc-5 netrin receptors A–D [UNC5A–D]) play essential roles for central nervous system (CNS) development, mediating axonal and neuronal navigation....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr