- Effects of Mesenchymal Stem Cells Treatment on Radiation-Induced Proctitis in Rats
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Kim WH, Yoo JH, Yoo IK, Kwon CI, Hong SP
- KMID: 2539559
- Yonsei Med J.
- 2023 Mar;64(3):167-174.
- doi: 10.3349/ymj.2022.0342
Purpose: There are no effective treatment methods with which to control complications of radiation proctitis with fistula or recurrent bleeding following radiation treatment for prostate, cervical, or rectal cancer. Mesenchymal... -
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- Establishment of a novel experimental model of infected anal fistula in rat
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Zhao M, Wang A, Zhang L, Yu H
- KMID: 2530962
- Lab Anim Res.
- 2022 Jun;38(2):128-131.
- doi: 10.1186/s42826-022-00125-4
Refractory Crohn’s-like enterocutaneous fistula indicates the aggressive manifestation and lead to poor prognosis of patients. The development of multidisciplinary strategies for fistula administration largely subjects to the deficiency of animal... -
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- Assessment of Bacterial Communities Within the Biofilm of Bladder Calculi in the Neurogenic Bladder Rat Model Following Spinal Cord Injury
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Lee JW, Lee SS, Yang SH, Choe HS
- KMID: 2528263
- Int Neurourol J.
- 2022 Mar;26(1):26-30.
- doi: 10.5213/inj.2142182.091
Purpose: To develop a rat model of bladder calculi in the neurogenic bladder following spinal cord injury (SCI) and assess bacterial communities within the biofilm of bladder calculi using denaturing... -
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- Polydeoxyribonucleotide and Polynucleotide Improve Tendon Healing and Decrease Fatty Degeneration in a Rat Cuff Repair Model
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Hwang JT, Lee SS, Han SH, Sherchan B, Panakkal JJ
- KMID: 2522575
- Tissue Eng Regen Med.
- 2021 Dec;18(6):1009-1020.
- doi: 10.1007/s13770-021-00378-5
BACKGROUND: After surgical repair of chronic rotator cuff tears, healing of the repaired tendons often fails and is accompanied by high-level fatty degeneration. Our purpose was to explore the effects... -
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- The effect of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion
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Hwang S, Chung CJ, Choi YJ, Kim T, Kim KH
- KMID: 2468640
- Korean J Orthod.
- 2020 Jan;50(1):42-51.
- doi: 10.4041/kjod.2020.50.1.42
OBJECTIVE: The objective of this study was to evaluate the effects of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion. METHODS: Sixty male Sprague–Dawley rats were... -
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- Bladder Augmentation Using Lyoplant® : First Experimental Results in Rats
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Winde F, Backhaus K, Zeitler JA, Schlegel N, Meyer T
- KMID: 2467056
- Tissue Eng Regen Med.
- 2019 Dec;16(6):645-652.
- doi: 10.1007/s13770-019-00209-8
BACKGROUND: Congenital defects of the urinary bladder (micro- or contracted bladder, bladder exstrophy) remain a challenging problem for pediatric surgeons. Even when conservative treatment options are fully exhausted, irreversible renal... -
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- Potential involvement of glycogen synthase kinase (GSK)-3β in a rat model of multiple sclerosis: evidenced by lithium treatment
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Ahn M, Kim J, Park C, Cho J, Jee Y, Jung K, Moon C, Shin T
- KMID: 2390426
- Anat Cell Biol.
- 2017 Mar;50(1):48-59.
- doi: 10.5115/acb.2017.50.1.48
Glycogen synthase kinase (GSK)-3β has been known as a pro-inflammatory molecule in neuroinflammation. The involvement of GSK-3β remains unsolved in acute monophasic rat experimental autoimmune encephalomyelitis (EAE). The aim of... -
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- Procaine Attenuates Pain Behaviors of Neuropathic Pain Model Rats Possibly via Inhibiting JAK2/STAT3
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Li D, Yan Y, Yu L, Duan Y
- KMID: 2351672
- Biomol Ther.
- 2016 Sep;24(5):489-494.
- doi: 10.4062/biomolther.2016.006
Neuropathic pain (NPP) is the main culprit among chronic pains affecting the normal life of patients. Procaine is a frequently-used local anesthesia with multiple efficacies in various diseases. However, its... -
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- Topical Products for Human Hair Regeneration: A Comparative Study on an Animal Model
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Orasan MS, Bolfa P, Coneac A, Muresan A, Mihu C
- KMID: 2429483
- Ann Dermatol.
- 2016 Feb;28(1):65-73.
- doi: 10.5021/ad.2016.28.1.65
BACKGROUND: Hair loss and hair growth is the subject of tremendous amount of research. OBJECTIVE: This study investigated the efficacy of three chemical treatments used in humans for hair loss, using... -
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- Development of animal model for Bisphosphonates-related osteonecrosis of the jaw (BRONJ)
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Jang HW, Kim JW, Cha IH
- KMID: 2381890
- Maxillofac Plast Reconstr Surg.
- 2015 Jul;37(7):18.
- doi: 10.1186/s40902-015-0020-6
BACKGROUND: The aim of this study is to develop a rat model of bisphosphonates-related osteonecrosis of the jaw (BRONJ) that would be verified with clinical, radiological and histological examination, and... -
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- Olanzapine Attenuates Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve Ligation
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Fukuda T, Yamashita , Hisano S, Tanaka M
- KMID: 2149462
- Korean J Pain.
- 2015 Jul;28(3):185-192.
- doi: 10.3344/kjp.2015.28.3.185
BACKGROUND: Neuropathic pain is a global clinical problem; nevertheless, nerve injury treatment methods remain limited. Olanzapine has antinociceptive and anti-nueropathic properties; however, its preventive effects have not been assessed in... -
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- Enhanced Efficacy of Human Brain-Derived Neural Stem Cells by Transplantation of Cell Aggregates in a Rat Model of Parkinson's Disease
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Shin ES, Hwang O, Hwang YS, Suh JK, Chun YI, Jeon SR
- KMID: 2018095
- J Korean Neurosurg Soc.
- 2014 Nov;56(5):383-389.
- doi: 10.3340/jkns.2014.56.5.383
OBJECTIVE: Neural tissue transplantation has been a promising strategy for the treatment of Parkinson's disease (PD). However, transplantation has the disadvantages of low-cell survival and/or development of dyskinesia. Transplantation of... -
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- Chlorogenic Acid Decreases Retinal Vascular Hyperpermeability in Diabetic Rat Model
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Shin JY, Sohn J, Park KH
- KMID: 1786971
- J Korean Med Sci.
- 2013 Apr;28(4):608-613.
- doi: 10.3346/jkms.2013.28.4.608
To evaluate the effect of chlorogenic acid (CGA), a polyphenol abundant in coffee, on retinal vascular leakage in the rat model of diabetic retinopathy, Sprague-Dawley rats were divided into four... -
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- Therapeutic potentials occurring during the early differentiation process of mesenchymal stem cells in a rats model with thioacetamide-induced liver fibrosis
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Choi ST, Hwang S, Hong HN, Won YJ, Ahn CS, Ha TY, Song GW, Jung DH, Park GC, Lee SG
- KMID: 2243165
- Korean J Hepatobiliary Pancreat Surg.
- 2013 Feb;17(1):21-33.
- doi: 10.14701/kjhbps.2013.17.1.21
BACKGROUNDS/AIMS: Mesenchymal stem cells (MSCs) have the capacity to differentiate into hepatocytes, The purpose of this study is to investigate the MSCs' differentiation process and therapeutic potentials by comparing isolated... -
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- The Effect of Hyaluronate-Carboxymethyl Cellulose on Bone Graft Substitute Healing in a Rat Spinal Fusion Model
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Lee JH, Jeong BO
- KMID: 2190438
- J Korean Neurosurg Soc.
- 2011 Nov;50(5):409-414.
- doi: 10.3340/jkns.2011.50.5.409
OBJECTIVE: The aim of this study was to evaluate the impact of sodium hyaluronate-sodium carboxymethyl cellulose (HA-CMC), an anti-adhesive material for spinal surgery, on bone fusion by applying it to... -
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- Survival, Exercise Capacity, and Left Ventricular Remodeling in a Rat Model of Chronic Mitral Regurgitation: Serial Echocardiography and Pressure-Volume Analysis
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Kim KH, Kim YJ, Lee SP, Kim HK, Seo JW, Sohn DW, Oh BH, Park YB
- KMID: 2297920
- Korean Circ J.
- 2011 Oct;41(10):603-611.
- doi: 10.4070/kcj.2011.41.10.603
BACKGROUND AND OBJECTIVES: The aims of this study were to establish a reliable model of chronic mitral regurgitation (MR) in rats and verify the pathophysiological features of this model by... -
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- Serial MR Imaging of Intramuscular Hematoma: Experimental Study in a Rat Model with the Pathologic Correlation
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Lee YS, Kwon ST, Kim JO, Choi ES
- KMID: 991684
- Korean J Radiol.
- 2011 Feb;12(1):66-77.
- doi: 10.3348/kjr.2011.12.1.66
OBJECTIVE: We wanted to demonstrate the temporal changes of the magnetic resonance imaging (MRI) findings in experimentally-induced intramuscular hematomas in rats and to correlate these data with the concurrent pathologic... -
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- Effects of Electrical Stimulation and Weight-Supported Treadmill Gait Simulation on Apoptosis in the Muscles of Rats with Spinal Cord Injury
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Kim JH, Bang MS
- KMID: 2326490
- J Korean Acad Rehabil Med.
- 2010 Dec;34(6):613-621.
OBJECTIVE: To assess the effect of electrical stimulation and weight-supported treadmill gait simulation on apoptosis in the muscles of rats with spinal cord injury. METHOD: Twenty seven rats with a model... -
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- Neuronal Hyperexcitability Mediates Below-Level Central Neuropathic Pain after Spinal Cord Injury in Rats
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Park ES, Jeon Y, Cho DC, Youn DH, Gwak YS
- KMID: 2312071
- Lab Anim Res.
- 2010 Sep;26(3):225-232.
Spinal cord injury often leads to central neuropathic pain syndromes, such as allodynic and hyperalgesic behaviors. Electrophysiologically, spinal dorsal horn neurons show enhanced activity to non-noxious and noxious stimuli as... -
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- The Changes of the Erectile Function and Histology of the Corpus Cavernosum in a Rat Model of Metabolic Syndrome
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Kim SD, Cho SY, Sohn DW, Lee DS, Jeong MS, Kim DB, Kim HS, Cho YH, Park CW, Kim SW
- KMID: 2226548
- Korean J Androl.
- 2008 Dec;26(4):187-196.
PURPOSE: We evaluated the changes of the erectile function and histology of the corpus cavernosum in a rat model of metabolic syndrome. MATERIALS AND METHODS: We used male spontaneous hypertensive rats... -
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