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Radiofrequency Ablation versus Stereotactic Body Radiation Therapy in the Treatment of Colorectal Cancer Liver Metastases

Yu J, Kim DH, Lee J, Shin YM, Kim JH, Yoon SM, Jung J, Kim JC, Yu CS, Lim SB, Park IJ, Kim TW, Hong YS, Kim SY, Kim JE, Park Jh, Kim SY

Purpose This study aimed to compare the treatment outcomes of radiofrequency ablation (RFA) and stereotactic body radiation therapy (SBRT) for colorectal cancer liver metastases (CRLM) and to determine the favorable treatment...
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Genetic variations affecting response of radiotherapy

Choi EK

Radiation therapy (RT) is a very important treatment for cancer that irradiates a large amount of radiation to lead cancer cells and tissues to death. The progression of RT in...
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An overview of radiation-induced heart disease

Ellahham S, Khalouf A, Elkhazendar M, Dababo N, Manla Y

Radiation therapy (RT) has dramatically improved cancer survival, leading to several inevitable complications. Unintentional irradiation of the heart can lead to radiation-induced heart disease (RIHD), including cardiomyopathy, pericarditis, coronary artery...
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Craniospinal irradiation for respiratory failure secondary to central nervous system Erdheim-Chester disease

Prasad RN, Kobalka PJ, Perlow HK, Prevedello DM, Blakaj DM, Raval RR, Palmer JD

Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis typically featuring lower extremity osteosclerosis (96%) from Langerin-negative histiocytes with fibrosis. Central nervous system (CNS)-only disease is extremely rare, and particularly...
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Post-radiation neutrophil-to-lymphocyte ratio is a prognostic marker in patients with localized pancreatic adenocarcinoma treated with anti-PD-1 antibody and stereotactic body radiation therapy

Reddy AV, Hill CS, Sehgal S, Zheng L, He J, Laheru DA, Jesus-Acosta AD, Herman JM, Meyer J, Narang AK

Purpose: To investigate the role of pre- and post-stereotactic body radiation therapy (SBRT) neutrophil-to-lymphocyte ratio (NLR) in patients with localized pancreatic cancer treated with anti-PD-1 (programmed cell death protein-1) antibody...
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Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma

Kim N, Lim DH

Optic pathway glioma (OPG) is a rare tumor located in optic nerve, optic tract, or optic chiasm. Treatment options for OPG include surgery, radiation therapy (RT), and chemotherapy. Although RT...
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Radiation Response Prediction Model Based on Integrated Clinical and Genomic Data Analysis

Jang BS, Chang JH, Jeon SH, Song MG, Lee KH, Im SA, Kim JI, Kim TY, Chie EK

Purpose The value of the genomic profiling by targeted gene-sequencing on radiation therapy response prediction was evaluated through integrated analysis including clinical information. Radiation response prediction model was constructed based on...
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PA1 cells containing a truncated DNA polymerase β protein are more sensitive to gamma radiation

Patra A, Nag A, Chakraborty A, Bhattacharyya N

Purpose: DNA polymerase β (Polβ) acts in the base excision repair (BER) pathway. Mutations in DNA polymerase β (Polβ) are associated with different cancers. A variant of Polβ with a...
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Reviewing the potential role of radiation therapy in gallbladder cancer: an update

Kumar D, Kiran NM, Khosla D

Gallbladder cancer is a highly malignant disease with a poor prognosis. It is the most common cancer of the biliary tract pathway. Although surgery remains the treatment of choice for...
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Hospital readmissions for patients with prostate cancer are higher after radiotherapy than after prostatectomy

Kesavan A, Vickneson K, Esuvaranathan K

Purpose: To compare hospital readmissions, biochemical recurrence rates, incidence of metastasis, and cancer-specific and overall mortality for prostate cancer patients undergoing radiotherapy vs. radical prostatectomy. The secondary outcome was to...
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Clinicopathological differences in radiation-induced organizing hematomas of the brain based on type of radiation treatment and primary lesions

Kim MS, Kim SH, Chang JH, Park M, Cha YJ

Background: Radiation-induced organizing hematoma (RIOH) is a sporadic form of cavernous hemangioma (CH) that occurs after cerebral radiation. RIOH lesions are distinct histologically from de novo CH; however, detailed research...
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Long-term Survivals, Toxicities and the Role of Chemotherapy in Early-Stage Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Radiation Therapy: A Retrospective Study with 15-Year Follow-up

Wang L, Miao J, Huang H, Chen B, Xiao X, Zhu M, Liang Y, Xiao W, Huang S, Peng Y, Deng X, Lv X, Xia W, Xiang Y, Guo X, Han F, Zhao C

Purpose This study was aimed to investigate long-term survivals and toxicities of early-stage nasopharyngeal carcinoma (NPC) in endemic area, evaluating the role of chemotherapy in stage II patients. Materials and Methods...
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Re-irradiation with Moderate Hypo-fractionation Using Intensity Modulated Photon or Proton Radiation Therapy in Locally Recurrent Squamous Cell Carcinoma of Nasopharynx

Nam H, Ahn YC, Yang K, Oh D, Noh JM

Purpose This study aimed to analyze the treatment outcomes of locally recurrent nasopharyngeal cancer (NPC) patients following moderate hypo-fractionation re-irradiation (re-RT). Materials and Methods Sixty locally recurrent NPC patients underwent hypo-fractionation...
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Design of Multipurpose Phantom for External Audit on Radiotherapy

Lim S

Purpose: This study aimed to design a multipurpose dose verification phantom for external audits to secure safe and optimal radiation therapy. Methods: In this study, we used International Atomic Energy Agency...
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Evaluating the Effects of Dose Rate on Dynamic Intensity-Modulated Radiation Therapy Quality Assurance

Kim KH, Back TS, Chung EJ, Suh TS, Sung W

Purpose: To investigate the effects of dose rate on intensity-modulated radiation therapy (IMRT) quality assurance (QA). Methods: We performed gamma tests using portal dose image prediction and log files of a...
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Status of Domestic and International Recommendations for Protection Design and Evaluation of Medical Linear Accelerator Facilities

Choi SH, Shin DO, Shin Ji, Kwon NH, Ahn SH, Kim DW

Various types of high-precision radiotherapy, such as intensity-modulated radiation therapy (IMRT), tomotherapy (Tomo), and stereotactic body radiation therapy have been available since 1997. After being covered by insurance in 2015,...
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Impact of somatic mutations on clinical and pathologic outcomes in borderline resectable and locally advanced pancreatic cancer treated with neoadjuvant chemotherapy and stereotactic body radiotherapy followed by surgical resection

Reddy AV, Hill CS, Sehgal S, Ding D, Hacker-Prietz A, He J, Zheng L, Herman JM, Meyer J, Narang AK

Purpose: The purpose of this study was to determine if somatic mutations are associated with clinical and pathologic outcomes in patients with borderline resectable pancreatic cancer (BRPC) or locally advanced...
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Efficacy and safety of sequential neoadjuvant chemotherapy and short-course radiation therapy followed by delayed surgery in locally advanced rectal cancer: a single-arm phase II clinical trial with subgroup analysis between the older and young patients

Bananzadeh A, Hafezi AA, Nguyen N, Omidvari S, Mosalaei A, Ahmadloo N, Ansari M, Mohammadianpanah M

Purpose: This study was performed to investigate the efficacy and safety of short-course radiation therapy (SCRT) and sequential chemotherapy followed by delayed surgery in locally advancer rectal cancer with subgroup...
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Current role of proton beam therapy in patients with hepatocellular carcinoma

Yoo GS, Yu JI, Park HC

Hepatocellular carcinoma (HCC) is the most common primary liver cancer, the sixth most common cancer, and the fourth leading cause of cancerrelated deaths worldwide. There are curative local treatment options...
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Prognostic Factor and Clinical Outcome in Stage III Non-Small Cell Lung Cancer: A Study Based on Real-World Clinical Data in the Korean Population

Kim HC, Ji W, Lee JC, Kim HR, Song SY, Choi CM, Korean Association for Lung Cancer, Korea Central Cancer Registry

Purpose The optimal treatment for patients with stage III non-small cell lung cancer (NSCLC) remains controversial. This study aimed to investigate prognostic factors and clinical outcome in stage III NSCLC using...
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