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Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum

Ha YR, Hwang BG, Hong Y, Yang HW, Lee SJ

The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the...
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Molecular characterization of tetracycline- and quinolone-resistant Aeromonas salmonicida isolated in Korea

Kim JH, Hwang SY, Son JS, Han JE, Jun JW, Shin SP, Choresca C, Choi YJ, Park YH, Park SC

The antibiotic resistance of 16 Aeromonas (A.) salmonicida strains isolated from diseased fish and environmental samples in Korea from 2006 to 2009 were investigated in this study. Tetracycline or quinolone...
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Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells

Kang DW, Min G, Park DY, Hong KW, Min DS

Rebamipide a gastroprotective drug, is clinically used for the treatment of gastric ulcers and gastritis, but its actions on gastric cancer are not clearly understood. Phospholipase D (PLD) is overexpressed...
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Quinolone-resistant Shigella flexneri Isolated in a Patient Who Travelled to India

Jeon YL, Nam YS, Lim G, Cho SY, Kim YT, Jang JH, Kim J, Park M, Lee HJ

We report a recent case in which ciprofloxacin-resistant Shigella flexneri was isolated from a 23-yr-old female patient with a history of travel to India. Prior to her admission to our...
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Prevalence of Plasmid-mediated Quinolone Resistance and Its Association with Extended-spectrum Beta-lactamase and AmpC Beta-lactamase in Enterobacteriaceae

Jeong HS, Bae IK, Shin JH, Jung HJ, Kim SH, Lee JY, Oh SH, Kim HR, Chang CL, Kho WG, Lee JN

BACKGROUND: We investigated the prevalence of plasmid-mediated quinolone resistance and its association with extended-spectrum beta-lactamase (ESBL) and AmpC beta-lactamase in Enterobacteriaceae. METHODS: A total of 347 non-duplicated isolates of Enterobacteriaceae were...
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