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USP29 alleviates the progression of MASLD by stabilizing ACSL5 through K48 deubiquitination

Hu S, Wang Z, Zhu K, Shi H, Qin F, Zhang T, tian S, Ji Y, Zhang J, Qin J, She Z, Zhang X, Zhang P, Li H

Background/Aims: Metabolic dysfunction–associated steatotic liver disease (MASLD) is a chronic liver disease characterized by hepatic steatosis. Ubiquitin-specific protease 29 (USP29) plays pivotal roles in hepatic ischemiareperfusion injury and hepatocellular carcinoma,...
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