- Suppressors for Human Epidermal Growth Factor Receptor 2/4 (HER2/4): A New Family of Anti-Toxoplasmic Agents in ARPE-19 Cells
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Kim YH, Bhatt L, Ahn HJ, Yang Z, Lee WK, Nam HW
- KMID: 2395753
- Korean J Parasitol.
- 2017 Oct;55(5):491-503.
- doi: 10.3347/kjp.2017.55.5.491
The effects of tyrosine kinase inhibitors (TKIs) were evaluated on growth inhibition of intracellular Toxoplasma gondii in host ARPE-19 cells. The number of tachyzoites per parasitophorous vacuolar membrane (PVM) was... -
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- In Vitro and in Vivo Effects of Nitrofurantoin on Experimental Toxoplasmosis
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Yeo SJ, Jin C, Kim S, Park H
- KMID: 2164012
- Korean J Parasitol.
- 2016 Apr;54(2):155-161.
- doi: 10.3347/kjp.2016.54.2.155
Toxoplasma gondii is an important opportunistic pathogen that causes toxoplasmosis, which has very few therapeutic treatment options. The most effective therapy is a combination of pyrimethamine and sulfadiazine; however, their... -
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- Plasmodium vivax dhfr Mutations among Isolates from Malarious Areas of Iran
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Zaman J, Shahbazi A, Asgharzadeh M
- KMID: 1090611
- Korean J Parasitol.
- 2011 Jun;49(2):125-131.
- doi: 10.3347/kjp.2011.49.2.125
The use of sulfadoxine and pyrimethamine (SP) for treatment of vivax malaria is uncommon in most malarious areas, but Plasmodium vivax isolates are exposed to SP because of mixed infections... -
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- A Case of Cerebral Toxoplasmosis Following Tandem Autologous Stem Cell Transplantation in a Multiple Myeloma Patient
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Kim KH, Song KH, Jeon JH, Park WB, Park SW, Kim HB, Kim NJ, Kim I, Oh MD
- KMID: 2170307
- Infect Chemother.
- 2010 Jun;42(3):181-186.
- doi: 10.3947/ic.2010.42.3.181
Toxoplasmosis is a rare but fatal complication in hematopoietic stem cell transplant recipients, usually associated with allogeneic hematopoietic stem cell transplantation (HSCT). We report a case of cerebral toxoplasmosis in... -
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- Malaria in Korea
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Shim JC, Shin EH
- KMID: 1647507
- Korean J Infect Dis.
- 2002 Apr;34(2):104-135.
Since the national malaria eradication service (NMES) was implemented in 1959, extensive malariometric survey were conducted throughout the country. A total of 73,859 malaria cases of Plasmodium vivax were confirmed... -
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- A toxoplasmic uveitis case of a 60-year-old male in Korea
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Kim MH, Choi YK, Park YK, Nam HW
- KMID: 1040994
- Korean J Parasitol.
- 2000 Mar;38(1):29-31.
- doi: 10.3347/kjp.2000.38.1.29
A toxoplasmic uveitis case was reported on the focus of impairment of pathological findings and serological antibody titers after chemotherapy. A chief complaint of a 60-year-old male was a decreased... -
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- A Case of Toxoplasmosis Detected in Habitual Aborter
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Han SY, Yoon TK, Cha KY, Choi DH, Nam YS
- KMID: 2261339
- Korean J Obstet Gynecol.
- 1999 Feb;42(2):436-438.
Toxoplasma gondii, an intracellular coccidian protozoan, is the causative agent of toxoplasmosis, a widespread infection affecting various birds and mammals including humans. In immunocompetent hosts, the infection is usually asymptomatic... -
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- Resurgence of the Malaria Vivax Cases in Korea
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Shim JC, Kim DS
- KMID: 1551036
- Korean J Infect Dis.
- 1999 Feb;31(1):25-34.
Vivax malaria, which was once thought to be eradicable since more than 20 years ago, has made a dramatic resurgence since 1993 in the northern parts of Kyeonggi-do in the... -
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- Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates
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Baek EJ, Nam HW
- KMID: 662563
- Korean J Parasitol.
- 1998 Sep;36(3):191-198.
- doi: 10.3347/kjp.1998.36.3.191
The responses to antifolates of Toxoplasma gondii were investigated by measuring the dihydrofolate reductase (DHFR) activity, quantity of DHFR mRNA, and single-strand conformational polymorphism (SSCP) pattern. Pyrimethamine (PYM) and methotrexate... -
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- Effect of Pyrimethamine on DNA Synthesis of Germ Cells in Mice Testis
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Lee SK, Lee JS, Kim KA, Cho JS
- KMID: 1662201
- Korean J Urol.
- 1995 Apr;36(4):386-391.
Pyrimethamine(PYR) produces reversible infertility in mice. The antifertility effect of PYR is due to its antifolate action. PYR causes male infertility in Balb C mice in a dose dependent manner.... -
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- Culture of tissue-cyst forming strain of Toxoplasma gondii and the effect of cyclic AMP and pyrimidine salvage inhibitors
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Choi WY, Park SK, Nam HW, Kim DJ
- KMID: 1715453
- Korean J Parasitol.
- 1994 Mar;32(1):19-26.
- doi: 10.3347/kjp.1994.32.1.19
An in vitro culturing to examine the cyst stage of Toxoplasma gondii (ME49 strain) was investigated using murine peritoneal macrophages, and we also examined the effect of cAMP or DHFR... -
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- Effects of pyrimidine salvage inhibitors on uracil incorporation of Toxoplasma gondii
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Youn JH, Nam HW, Kim DJ, Choi WY
- KMID: 1043393
- Korean J Parasitol.
- 1990 Jun;28(2):79-84.
- doi: 10.3347/kjp.1990.28.2.79
Metabolic inhibitors which act in the process of pyrimidine salvage influenced on the uracil incorporation into nucleic acids of Toxoplasma. Inhibitors of dihydrofolate reductase, pyrimethamine and methotrexate, and inhibitors of... -
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- Chemotherapeutic efficacy of trimethoprim-sulfamethoxazole (Bactrim) in experimental murine toxoplasmosis
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Cho SW, Yong TS, Chung PR, Lee KT
- KMID: 1714973
- Korean J Parasitol.
- 1987 Dec;25(2):199-206.
- doi: 10.3347/kjp.1987.25.2.199
The chemotherapeutic efficacy of trimethoprim-sulfamethoxazole (Bactrim) in mice experimentally infected with Toxoplasma gondii was evaluated. The average survival days and survival rate of mice infected intraperitoneally with 1 x 10(5)... -
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