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Series with complete resolution of left atrial appendage thrombi with apixaban in elderly patients

Lee SH, Han S

No abstract available.
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New oral anticoagulants

Oh S

The most important and widely-prescribed drug for anticoagulation is a vitamin K antagonist such as warfarin although it has several limitations in clinical use. New oral anticoagulants (NOACs) have been...
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Recent Advances in Idiopathic Pulmonary Fibrosis

Park S, Lee EJ

  • KMID: 2320224
  • Tuberc Respir Dis.
  • 2013 Jan;74(1):1-6.
The concept on idiopathic pulmonary fibrosis (IPF) pathogenesis has progressed from chronic inflammation to aberrant wounding healing and even more to the current paradigms of a multifactorial and heterogeneous disease...
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Interstitial Lung Disease

Chung MP

  • KMID: 2319549
  • Tuberc Respir Dis.
  • 2011 Sep;71(3):163-171.
Recently published articles on interstitial lung disease (ILD) have focused on the accurate diagnosis of idiopathic pulmonary fibrosis (IPF), serum biomarkers, acute exacerbation of IPF, the prognostic factors of ILD...
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Simultaneous Closure of a Left Atrial Appendage through an Atrial Septal Defect and the Atrial Septal Defect

Song S, Lee OH, Kim JS, Cho IJ, Shim CY, Hong GR, Pak HN, Jang Y

Left atrial appendage (LAA) occlusion can be employed as an alternative treatment to oral anticoagulation in patients with atrial fibrillation to prevent embolic events. Atrial septal defect (ASD) may be...
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Stroke Update 2011: New Antithrombotics

Seo KD, Lee KY

  • KMID: 2288709
  • Korean J Stroke.
  • 2012 Aug;14(2):62-66.
Several new antithrombotic drugs have been developed and approved to use in clinical practice recently. Dabigatran, a direct thrombin inhibitor, and rivaroxaban, a factor Xa inhibitor, have been approved in...
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Efficacy and safety of deferiprone (Ferriprox), an oral iron-chelating agent, in pediatric patients

Won SC, Han DK, Seo JJ, Chung NG, Park SK, Park KB, Kook H, Lyu CJ

BACKGROUND: Iron overload is a predictable and life-threatening complication in patients dependent on the regular transfusion of RBCs. The aims of this study were to investigate the efficacy and safety...
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Recent advances in the management of venous thromboembolism

Ageno W

Venous thromboembolism (VTE) is a spectrum of diseases that includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Anticoagulant treatment is the mainstay of therapy for VTE. Unfractionated heparin (UFH)...
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4-hydroxy-2(E)-Nonenal facilitates NMDA-Induced Neurotoxicity via Triggering Mitochondrial Permeability Transition Pore Opening and Mitochondrial Calcium Overload

Choi IY, Lim JH, Kim C, Song HY, Ju C, Kim WK

N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity is one of the major causes for neuronal cell death during cerebral ischemic insult. Previously, we reported that the final product of lipid membrane peroxidation 4-hydroxy-2E-nonenal...
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Korean Guideline for Iron Chelation Therapy in Transfusion-Induced Iron Overload

Jang JH, Lee JH, Yoon SS, Jo DY, Kim HJ, Chung J, Lee JW

Many Korean patients with transfusion-induced iron overload experience serious clinical sequelae, including organ damage, and require lifelong chelation therapy. However, due to a lack of compliance and/or unavailability of an...
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Focused Update on Primary Stroke Prevention in Patients with Atrial Fibrillation in Korean Clinical Practice Guidelines for Stroke

Park JM, Hong KS, Han SW, Kim HY, Cho YJ, Kang K, Yu KH, Rha JH, Heo JH, Kwon SU, Oh CW, Bae HJ, Lee BC, Yoon BW, Koo J

  • KMID: 2288694
  • Korean J Stroke.
  • 2012 Dec;14(3):106-115.
Pivotal clinical trials testing the efficacy of new antithrombotics for the prevention of stroke and systemic embolism in patients with atrial fibrillation have been published since the release of the...
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The Reconstruction of Nasal Septal Perforation with High Density Porous Polyethylene Covered with Fascia Lata: An Experimental Study on Rabbit Model

Yildirim G, Onar V, Sayin I, Onol SD, Aydin T

  • KMID: 2221871
  • Clin Exp Otorhinolaryngol.
  • 2011 Sep;4(3):137-141.
OBJECTIVES: Evaluation of a new material, high-density porous polyethylene (HDPP), which is covered with fascia lata, for experimental nasal septal perforation closure. METHODS: Twenty New Zealand albino rabbits were included and...
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Effect of Iron-Chelator Deferiprone on the In Vitro Growth of Staphylococci

Kim CM, Shin SH

The standard iron-chelator deferoxamine is known to prevent the growth of coagulase-negative staphylococci (CoNS) which are major pathogens in iron-overloaded patients. However, we found that deferoxamine rather promotes the growth...
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Pirfenidone Suppressed the Development of Glomerulosclerosis in the FGS/Kist mouse

Park HS, Bao L, Kim YJ, Cho IH, Lee CH, Hyun BH, Margolin S, Park YH

Pirfenidone(PFD) is a newly developed anti-fibrotic agent. We evaluated the effect of PFD for the prevention of renal fibrosis using a spontaneous progressive glomerulosclerosis animal model, FGS/Kist mice. Male and...
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